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General practitioners’ approaches to prostate-specific antigen testing in the north-east of the Netherlands
BackgroundThere is wide variation in clinical practice for the early detection of prostate cancer, not least because of the ongoing debate about the...
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Selective BET-bromodomain inhibition by JQ1 suppresses dendritic cell maturation and antigen-specific T-cell responses
Bromo- and extra-terminal domain (BET) inhibitors represent potential therapeutic approaches in solid and hematological malignancies that are...
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Predictive factors of tumor sink effect: Insights from 177Lu-Prostate-specific membrane antigen therapy
ObjectiveTumor sink effect (TSE) has been defined as; decreased uptake in healthy tissue with increased tumor sequestration of the...
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Efficacy and safety of onabotulinumtoxinA in patients with overactive bladder: subgroup analyses by sex and by serum prostate-specific antigen levels in men from a randomized controlled trial
PurposeWe aimed to assess onabotulinumtoxinA treatment outcomes by sex in patients with overactive bladder (OAB) and then explore the impact of serum...
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Current status of radioligand therapy and positron-emission tomography with prostate-specific membrane antigen
Prostate-specific membrane antigen (PSMA) is a transmembrane glycoprotein highly expressed by prostate cancer cells. PSMA-based radioligand therapy...
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Successful haploidentical transplantation using plasma exchange and post-transplantation cyclophosphamide for severe aplastic anemia patients with anti-human leukocyte antigen donor-specific antibodies
Haploidentical allogeneic hematopoietic stem cell transplantation (Haplo-HSCT) has emerged as a novel strategy to treat patients suffering from...
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Explorative analysis of a score predicting the therapy response of patients with metastatic, castration resistant prostate cancer undergoing radioligand therapy with 177Lu-labeled prostate-specific membrane antigen
ObjectiveUp to 60% of patients with metastatic, castration-resistant prostate cancer (mCRPC) treated with 177 Lu prostate-specific membrane antigen...
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Relationship between serum prostate-specific antigen and transrectal prostate sonographic findings in asymptomatic Ugandan males
BackgroundProstate disorders are among the leading causes of morbidity and mortality in men above the age of 40 years globally. Serum...
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Lymph node staging with fluorine-18 prostate specific membrane antigen 1007-positron emission tomography/computed tomography in newly diagnosed intermediate- to high-risk prostate cancer using histopathological evaluation of extended pelvic node dissection as reference
PurposeFluorine-18 ( 18 F) prostate–specific membrane antigen (PSMA) 1007 ( 18 F-PSMA-1007) is a radiotracer used in prostate cancer (PCa) staging. So...
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Associations of Prostate-Specific Antigen (PSA) Testing in the US Population: Results from a National Cross-Sectional Survey
Prostate-specific antigen (PSA) testing is one of the standard screening methods for prostate cancer (PC); however, a high proportion of men with...
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A study of antigen-specific anti-cytomegalovirus antibody reactivity in patients with systemic sclerosis and concomitant anti-Ro52 antibodies
Anti-Ro52 autoantibody (autoAb), highly prevalent in Sjogren’s syndrome (SjS) and systemic lupus erythematosus (SLE), is also frequent in systemic...
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[68 Ga]Ga-Prostate-Specific Membrane Antigen PET/CT: a novel method for imaging patients with hepatocellular carcinoma
PurposeProstate-specific membrane antigen (PSMA) is not only highly expressed on the surface prostate cancer cells but is also elevated during...
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Prostate-specific membrane antigen positron emission tomography (PSMA-PET) for local staging of prostate cancer: a systematic review and meta-analysis
PurposeProstate-specific membrane antigen positron emission tomography (PSMA-PET) has shown promise for detecting nodal and distant prostate cancer...
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Prostate specific antigen test uptake: a cross sectional study on elderly men in Western Iran
BackgroundProstate cancer (PCa) is the second most common malignancy in men worldwide and the incidence rate of PCa has been increasing in recent...
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Prostate-specific antigen increase after urethral catheterisation: fact or myth
BackgroundTo find out any association of urethral catheterisation with rise in serum PSA.
MethodsThis study was conducted in 80 patients of BPH who...
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Bacillus subtilis spores as adjuvants against avian influenza H9N2 induce antigen-specific antibody and T cell responses in White Leghorn chickens
Low-pathogenicity avian influenza H9N2 remains an endemic disease worldwide despite continuous vaccination, indicating the need for an improved...
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Evaluation of Mycobacterium tuberculosis specific antigen-stimulated CD27−CD38+IFN-γ+CD4+ T cells for discrimination of active tuberculosis
BackgroundActive tuberculosis (ATB) originates from primary Mycobacterium tuberculosis (MTB) infection or reactivation of latent tuberculosis....
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Multi-Specific CAR Targeting to Prevent Antigen Escape
Purpose of ReviewChimeric antigen receptor (CAR) T cell therapy has demonstrated remarkable remission induction rates for relapsed/refractory B cell...
