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Uncovering the molecular landscape of meningiomas and the impact of perioperative steroids on patient survival
BackgroundThe current literature on meningioma reveals a gap in knowledge regarding the impact of genetic factors on patient survival. Furthermore,...
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Role of adjuvant radiotherapy in atypical (WHO grade II) and anaplastic (WHO grade III) meningiomas: a systematic review
The systematic adoption of the histopathologic criteria provided by the 2016 update of the WHO classification of brain tumors has markedly increased...
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CD13 is a useful tool in the differential diagnosis of meningiomas with potential biological and prognostic implications
Meningiomas are common tumors of the central nervous system. Although their histological diagnosis is usually straightforward, their differential...
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A current review of spinal meningiomas: epidemiology, clinical presentation and management
PurposeTo provide an up-to-date review of the epidemiology, histopathology, molecular biology, and etiology of spinal meningiomas, as well as discuss...
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Radiotherapy for meningiomas
Meningiomas are the most common primary central nervous system neoplasm. Despite promising recent progress in elucidating the genomic landscape and...
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Evaluating anti-tumor activity of palbociclib plus radiation in anaplastic and radiation-induced meningiomas: pre-clinical investigations
PurposeMeningiomas are common brain tumors, the majority of which are considered benign. Despite surgery and/or radiation therapy, recurrence rates...
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Diagnostic neuroradiology of intracranial meningiomas presenting with hemorrhagic onset: a double center 14-year experience
PurposeThis study aims to increase awareness of the hemorrhagic presentation of intracranial meningiomas in the emergency department and present...
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Differentiating microcystic meningioma from atypical meningioma using diffusion-weighted imaging
PurposeMicrocystic meningioma (MCM) appears similar to atypical meningioma(AM) as per conventional diagnostic imaging. However, considering their...
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DNA methylation profiling of meningiomas highlights clinically distinct molecular subgroups
BackgroundIntroduction of the classification of brain tumours based on DNA methylation profile has significantly changed the diagnostic approach. Due...
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Incidence trends and survival analysis of atypical meningiomas: a population-based study from 2004 to 2018
PurposeAtypical meningiomas have histologic and clinical features that fall between those for benign and malignant meningiomas. The incidence of...
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Single versus multiple reoperations for recurrent intracranial meningiomas
PurposeTo identify the risk factors and management of the multiple recurrences and reoperations for intracranial meningiomas.
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Magnetic resonance imaging–based 3-dimensional fractal dimension and lacunarity analyses may predict the meningioma grade
ObjectiveTo assess whether 3-dimensional (3D) fractal dimension (FD) and lacunarity features from MRI can predict the meningioma grade.
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Resected WHO grade I meningioma and predictors of local control
IntroductionDespite optimal surgical resection, meningiomas may recur, with increasing grade and the degree of resection being predictive of risk. We...
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Landscape of genetic variants in sporadic meningiomas captured with clinical genomics
BackgroundMeningiomas are the most common primary central nervous system tumor. Previous studies have characterized recurrent genetic alterations...
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The Simpson grading: defining the optimal threshold for gross total resection in meningioma surgery
Classification of the extent of resection into gross and subtotal resection (GTR and STR) after meningioma surgery is derived from the Simpson...
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Clinical characteristics and management differences for grade II and III spinal meningiomas
PurposeThe majority of spinal meningiomas are grade I tumors, as defined by World Health Organization (WHO) classification making atypical (grade II)...
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MRI radiomics in the prediction of the volumetric response in meningiomas after gamma knife radiosurgery
PurposeThis report presents the first investigation of the radiomics value in predicting the meningioma volumetric response to gamma knife...
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Ganoderic acid A/DM-induced NDRG2 over-expression suppresses high-grade meningioma growth
PurposeN-myc downstream-regulated gene 2 (NDRG2) is down-regulated in grade-III meningioma [anaplastic meningioma (AM)] and associated with...
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Prognosis and histology of sporadic synchronous and metachronous meningiomas and comparative analyses with singular lesions
Synchronous or metachronous growth of multiple tumors (≥ 2) is found in up to 20% of meningioma patients. However, biological as well as histological...
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The prognostic role of the immunohistochemical expression of S100 in meningiomas
BackgroundDespite best clinical management, meningioma patients experience tumor recurrence. Efforts have been made to improve the prognostic...
