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Lung ultrasound score follows the chronic pulmonary insufficiency of prematurity trajectory in early infancy
Extremely preterm birth is associated with a high risk of chronic pulmonary insufficiency of prematurity (CPIP). Lung ultrasound score (LUS) proved...
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Critical functional lung volumes in neonatal intensive care: evidence and clinical applications
AbstractRespiratory disease is common in premature and sick newborn infants and can often necessitate the initiation of intensive care. Newborn...
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Meconium aspiration syndrome: a comprehensive review
Meconium aspiration syndrome (MAS) is a complex respiratory disease that continues to be associated with significant morbidities and mortality. The...
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Characterizing the urinary proteome of prematurity-associated lung disease in school-aged children
IntroductionAlthough different phenotypes of lung disease after preterm birth have recently been described, the underlying mechanisms associated with...
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Exogenous Surfactant as a Pulmonary Delivery Vehicle for Budesonide In Vivo
BackgroundLung inflammation is associated with many respiratory conditions. Consequently, anti-inflammatory medications, like glucocorticoids, have...
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Extraskeletal myxoid chondrosarcoma of the gingival: a rare case report and review of the literature
BackgroundExtraskeletal myxoid chondrosarcoma (EMC) is a rare malignant tumor described in the head and neck region, especially in the gingival. We...
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Prophylactic Sildenafil in Preterm Infants at Risk of Bronchopulmonary Dysplasia: A Pilot Randomized, Double-Blinded, Placebo-Controlled Trial
BackgroundBronchopulmonary dysplasia (BPD) is the need for oxygen therapy at 36 weeks postmenstrual age (PMA). Sildenafil has been shown to enhance...
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Simvastatin attenuates lung functional and vascular effects of hyperoxia in preterm rabbits
BackgroundBronchopulmonary dysplasia (BPD) remains a frequent complication following preterm birth, affecting respiratory health throughout life....
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Tools for assessing lung fluid in neonates with respiratory distress
BackgroundTransient tachypnea of the newborn (TTN), as a common cause of neonatal respiratory distress, needs to be distinguished from respiratory...
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Preventing bronchopulmonary dysplasia: new tools for an old challenge
Bronchopulmonary dysplasia (BPD) is the most prevalent chronic lung disease in infants and presents as a consequence of preterm birth. Due to the...
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Mechanosensitive Piezo channels mediate the physiological and pathophysiological changes in the respiratory system
Mechanosensitive Piezo ion channels were first reported in 2010 in a mouse neuroblastoma cell line, opening up a new field for studying the...
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Association between fluid overload and mortality in newborns: a systematic review and meta-analysis
Fluid overload (FO) is associated with higher rates of mortality and morbidity in pediatric and adult populations. The aim of this systematic review...
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Real-life effects, complications, and outcomes in 39 critically ill neonates receiving continuous kidney replacement therapy
BackgroundContinuous kidney replacement therapy (CKRT) has been expanded from simple kidney replacement therapy to the field of critical illness in...
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Non-invasive carbon dioxide monitoring in neonates: methods, benefits, and pitfalls
Wide fluctuations in partial pressure of carbon dioxide (PaCO 2 ) can potentially be associated with neurological and lung injury in neonates. Blood...
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Nasal HFOV versus nasal IPPV as a post-extubation respiratory support in preterm infants—a randomised controlled trial
Early and successful extubation prevents several morbidities in preterm newborns. Several secondary non-invasive respiratory modalities exist but...
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Concurrent pulmonary hypoplasia and congenital lobar emphysema in a young dog with tension pneumothorax: a rare congenital pulmonary anomaly
BackgroundPulmonary hypoplasia (PH) and congenital lobar emphysema (CLE) are very rare congenital pulmonary anomalies in veterinary medicine. PH...
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PATET ratio by Doppler echocardiography: noninvasive detection of pediatric pulmonary arterial hypertension
AbstractPulmonary artery acceleration time (PAT) and PAT: ejection time (PATET) ratio are echocardiographic measurements of pulmonary arterial...
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Lung function between 8 and 15 years of age in very preterm infants with fetal growth restriction
BackgroundThe impact of intrauterine growth restriction (IUGR) on lung function in very preterm children is largely unknown as current evidence is...