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Serum proteome profiles in patients treated with targeted temperature management after out-of-hospital cardiac arrest
BackgroundDefinition of temporal serum proteome profiles after out-of-hospital cardiac arrest may identify biological processes associated with...
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Reconsidering adsorption in hemodialysis: is it just an epiphenomenon? A narrative review
Since the first attempt at extracorporeal renal replacement therapy, renal replacement therapy has been constantly improved. In the field of...
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Immune Checkpoint Molecules and Maternal–Fetal Immunity
Purpose of ReviewBecause the fetus expresses paternally-derived foreign antigens, pregnancy poses unique immune challenges. The maternal immune...
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Analytical and Functional Similarity of the Biosimilar Candidate ABP 654 to Ustekinumab Reference Product
Background and ObjectiveABP 654 is a proposed biosimilar to ustekinumab reference product (RP), a human immunoglobulin isotype class G subclass 1...
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Cardiac Xenotransplantation: a New Frontier for Advanced Heart Failure
Purpose of reviewCardiac transplantation is a critical treatment for patients with advanced heart failure, offering the ability to markedly improve...
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End-of-treatment 18[F]-FDG PET can predict early progression in patients receiving bendamustine-rituximab for follicular lymphoma in first relapse: a prospective West Japan hematology Study Group (W-JHS) NHL01 trial
Response determined by 18[F]-fluoro-2-deoxy- d -glucose ( 18 F-FDG) positron emission tomography (PET)–CT after induction therapy can predict...
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Atypical phenotypes and novel OCRL variations in southern Chinese patients with Lowe syndrome
BackgroundLowe syndrome is characterized by the presence of congenital cataracts, psychomotor retardation, and dysfunctional proximal renal tubules....
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Enhancing gestational diabetes mellitus risk assessment and treatment through GDMPredictor: a machine learning approach
BackgroundGestational diabetes mellitus (GDM) is a serious health concern that affects pregnant women worldwide and can lead to adverse pregnancy...
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A case of clinically aggressive EBV-negative ENKTL in a non-Asian female patient
BackgroundThe patient was a 65-year-old White woman who presented to dermatology with a painless, rapidly growing exophytic nodule on her left upper...
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End of induction [18F]FDG PET is prognostic for progression-free survival and overall survival in follicular lymphoma patients enrolled in the FOLL12 trial
PurposeTo evaluate the reliability of the Deauville score (DS) in therapy response assessment and to define the prognostic value of the metabolic...
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Comparison of the effects of pre-dilution and post-dilution online hemodiafiltration on the levels of inflammatory markers, lymphocytes, and platelets
Online hemodiafiltration (OL-HDF) is a blood purification therapy based on diffusion and ultrafiltration and is classified into two types according...
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A clinical approach to tubulopathies in children and young adults
Kidney tubules are responsible for the preservation of fluid, electrolyte and acid-base homeostasis via passive and active mechanisms. These...
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Exhaled biomarkers in adults with non-productive cough
BackgroundChronic cough is a common condition but disease mechanisms are not fully understood. Our aim was to study respiratory biomarkers from the...
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NF-κB in biology and targeted therapy: new insights and translational implications
NF-κB signaling has been discovered for nearly 40 years. Initially, NF-κB signaling was identified as a pivotal pathway in mediating inflammatory...
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Proteomics for heart failure risk stratification: a systematic review
BackgroundHeart failure (HF) is a complex clinical syndrome with persistently high mortality. High-throughput proteomic technologies offer new...
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Early Progressing Follicular Lymphoma
Purpose of ReviewFollicular lymphoma is an indolent lymphoma which does not limit life expectancy in most patients; however, approximately 20% of...
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Salivary proteomic profile of young adults before and after the practice of interval exercise: preliminary results
The practice of exercise can change biological markers. Thus, the use of saliva to define possible biomarkers has increased with the advances in...
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Human airway tuft cells influence the mucociliary clearance through cholinergic signalling
BackgroundAirway tuft cells, formerly called brush cells have long been described only morphologically in human airways. More recent RNAseq studies...
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Reno-protective effects of perioperative dexmedetomidine in kidney transplantation: a systematic review and meta-analysis of randomized controlled trials
Background and objectiveThere is currently no FDA-approved medical therapy for delayed graft function (DGF). Dexmedetomidine (DEX) has multiple...
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Psychosocial moderators of polygenic risk scores of inflammatory biomarkers in relation to GrimAge
GrimAge acceleration has previously predicted age-related morbidities and mortality. In the current study, we sought to examine how GrimAge is...