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Child Neurology in the 20th Century
Although considered a relatively new subspecialty, child neurology traces its origins to the Hippocratic descriptions of seizures and other...
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Neurostimulation therapy for epilepsy
Neurostimulation therapy for epilepsy is growing in popularity. By appropriate targeting of applied electrical activation at selected nervous system...
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Isolated injury of the cuboid bone
The purpose of this study was to describe isolated injury of the cuboid bone as a potentially radiographically occult cause of foot pain. The...
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Symptom control in cancer patients: the clinical pharmacology and therapeutic role of suppositories and rectal suspensions
Rectally administered medications are essential in palliative medicine, particularly in the last days of life. They are underutilized. The...
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Molsidomine enhances the protective activity of valproate against pentylenetetrazole-induced seizures in mice
Molsidomine (25 mg kg −1 ), a donor of nitric oxide, commonly used in the treatment of coronary artery disease, enhanced the protective activity of...
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Clinical Predictors of Depression in Patients with Low-Grade Brain Tumors: Consideration of a Neurologic Versus a Psychogenic Model
Few studies have examined quality of life issues in patients with brain tumors, though co** with cancer is stressful and is associated with...
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Effects of Psychotropic Drugs on Seizure Threshold
Psychotropic drugs, especially antidepressants and antipsychotics, may give rise to some concern in clinical practice because of their known ability...
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Emotional disturbances following traumatic brain injury
Mood disturbances are common sequelae of traumatic brain injury (TBI), but the scientific database for such disorders is very limited in descriptive,...
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Morphine in cancer pain management: a practical guide
Morphine is the most practical and versatile analgesic for the relief of severe pain associated with advanced cancer. Information is available in...
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Use of Antiepileptics in Traumatic Brain Injury: A Review for Psychiatrists
In recent years, the number of new antiepileptic agents has been growing, as have the potential applications. Traumatic brain injury (TBI) patients...
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New antiepileptic drugs
Finding a niche for each antiepileptic drug has become challenging as more new agents are approved. In this article, the most recent information...
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Phenytoin hypersensitivity syndrome
Phenytoin hypersensitivity syndrome (PHS) is a rare, and important entity characterized by rash, fever, lymphadenopathy, leukocytosis with atypical...
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Anti-epileptic drugs in the preventive treatment of migraine headache: a brief review
Anti-epileptic drugs are employed for the prophylactic treatment of migraine. Valproic acid and its sodium salt (divalproex) have been shown to be...
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Methadone for relief of cancer pain: a review of pharmacokinetics, pharmacodynamics, drug interactions and protocols of administration
Methadone, a synthetic opioid, has unique pharmacodynamics and pharmacokinetics, which contribute to its unique ability to relieve pain unresponsive...
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Drug Interactions with Colesevelam Hydrochloride, a Novel, Potent Lipid-Lowering Agent
Colesevelam hydrochloride (colesevelam) is a novel, potent, bile acid–binding agent that has been shown to lower LDL cholesterol a mean of 19% at a...
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Psychoanalysis and Psychosis: Trends and Developments
This paper presents the basic principles of insight-oriented therapy for schizophrenia, emphasizing the effectiveness of this approach: each...
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Taking antiretroviral therapy for HIV infection
OBJECTIVE: To describe how people with HIV understand and experience the problem of adhering to antiretroviral medication regimens.
DESIGN: We...
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The Next Wave of Anticonvulsants
Since December 1999, 3 drugs have been cleared for marketing by the US Food and Drug Administration for the treatment of partial-onset seizures in...