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Effect of invasive mechanical ventilation on the diversity of the pulmonary microbiota
Pulmonary microbial diversity may be influenced by biotic or abiotic conditions (e.g., disease, smoking, invasive mechanical ventilation (MV), etc.)....
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Changes in the levels of free sialic acid during ex vivo lung perfusion do not correlate with pulmonary function. Experimental model
BackgroundEx vivo lung perfusion (EVLP) constitutes a tool with great research potential due to its advantages over in vivo and in vitro models....
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Identification of non-coding RNA signatures in idiopathic pulmonary fibrosis
BackgroundIdiopathic pulmonary fibrosis (IPF) is a deadly, chronic, progressive, irreversible interstitial lung disease characterized by the...
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Downregulation of HMGCS2 mediated AECIIs lipid metabolic alteration promotes pulmonary fibrosis by activating fibroblasts
BackgroundAbnormal lipid metabolism has recently been reported as a crucial signature of idiopathic pulmonary fibrosis (IPF). However, the origin and...
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Effects of acupuncture at Feishu (BL13) and Tianshu (ST25) on pulmonary function and tissue inflammation in asthma model rats
ObjectiveTo compare the effects of Feishu (BL13) combined with Tianshu (ST25) and Feishu (BL13) alone on pulmonary function and tissue inflammation...
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Increased CAP37 Expression in Stable Chronic Obstructive Pulmonary Disease
ObjectiveCationic antimicrobial protein of 37 kDa (CAP37), a neutrophil-derived protein originally identified for its antimicrobial activity, is now...
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Pasteurella multocida activates Rassf1-Hippo-Yap pathway to induce pulmonary epithelial apoptosis
Pasteurella multocida is an opportunistic zoonotic pathogen that primarily causes fatal respiratory diseases, such as pneumonia and respiratory...
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Modulation of pulmonary immune function by inhaled cannabis products and consequences for lung disease
The lungs, in addition to participating in gas exchange, represent the first line of defense against inhaled pathogens and respiratory toxicants....
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Role of thioredoxin in chronic obstructive pulmonary disease (COPD): a promising future target
IntroductionThioredoxin (Trx) is a secretory protein that acts as an antioxidant, redox regulator, anti-allergic, and anti-inflammatory molecule. It...
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Clinical characteristics of venous thromboembolism onset from severe high altitude pulmonary edema in plateau regions
BackgroundTo investigate venous thromboembolism (VTE) in hospitalized patients with severe high altitude pulmonary edema (HAPE), we performed a...
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Congenital pulmonary airway malformation in a 5 month old boy, complicated by pneumonia
Congenital cystic lesions of the lung are rare. The most common congenital anomaly among them, involving the lower respiratory tract, is congenital...
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Pulmonary sclerosing pneumocytoma: clinical features and prognosis
BackgroundPulmonary sclerosing pneumocytoma is a kind of rare benign pulmonary tumor with potential malignancy. The clinical features, risk factors...
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Early resection of a rare congenital pulmonary airway malformation causing severe progressive respiratory distress in a preterm neonate: a case report and review of the literature
BackgroundCongenital pulmonary airway malformations (CPAMs) are a heterogenous collection of congenital lung malformations, often diagnosed...
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Serum Rcn3 level is a potential diagnostic biomarker for connective tissue disease-associated interstitial lung disease and reflects the severity of pulmonary function
BackgroundAlthough reticulocalbin 3 (Rcn3) has a critical role in alveolar epithelial function as well as in pathogenesis of pulmonary fibrosis, no...
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Therapeutic potential of Lianhua Qingke in airway mucus hypersecretion of acute exacerbation of chronic obstructive pulmonary disease
BackgroundLianhua Qingke (LHQK) is an effective traditional Chinese medicine used for treating acute tracheobronchitis. In this study, we evaluated...
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Decreased humoral immune response in the bronchi of rapid decliners with chronic obstructive pulmonary disease
BackgroundIdentification of COPD patients with a rapid decline in FEV1 is of particular interest for prognostic and therapeutic reasons.
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The Oral-Vascular-Pulmonary Infection Route: a Pathogenic Mechanism Linking Oral Health Status to Acute and Post-Acute COVID-19
Purpose of ReviewIn recent years, much attention has focused on the role of poor oral health in the development or worsening of systemic diseases,...
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HB-EGF-induced IL-8 secretion from airway epithelium leads to lung fibroblast proliferation and migration
BackgroundWe have reported that heparin-binding epidermal growth factor (HB-EGF) is increased in patients with chronic obstructive pulmonary disease...
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Pulmonary sclerosing pneumocytoma containing spindle cells with sarcomatoid features: a case report with literature review
BackgroundPulmonary sclerosing pneumocytoma (PSP) is an uncommon benign neoplasm originated from pneumocyte and PSP with malignant transformation is...
