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Incidence of hypoglycaemia in patients with type-2 diabetes taking multiple glucose lowering therapies during Ramadan: the PROFAST Ramadan Study
ObjectiveTo assess the incidence of hypoglycemia in people with type-2 diabetes mellitus (T2DM) on three or more anti-diabetic medications during...
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Carotid ultrasonography as a strategy to optimize cardiovascular risk management in type 1 diabetes: a cohort study
Background and aimsAlthough cardiovascular disease (CVD) remains the leading cause of mortality in type 1 diabetes (T1D), the use of cardioprotective...
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Qatar Diabetes Mobile Application Trial (QDMAT): an open-label randomised controlled trial to examine the impact of using a mobile application to improve diabetes care in type 2 diabetes mellitus—a study protocol
BackgroundMobile health (mHealth) is increasingly advocated for diabetes management. It is unclear if mobile applications are effective in improving...
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Hypoglycaemia in diabetes: do we think enough of the cause? An observational study on prevalence and causes of hypoglycaemia among patients with type 2 diabetes in an out-patient setting in Sri Lanka
BackgroundHypoglycaemia is a feared experience for people with diabetes. We aimed to study the prevalence and causes of hypoglycaemia among Sri...
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Insulin Pump Treatment in Adults with Type 1 Diabetes in the Capital Region of Denmark: Design and Cohort Characteristics of the Steno Tech Survey
IntroductionInsulin pump therapy can improve quality of life and glycaemic outcomes for many people with type 1 diabetes (T1D). The multidimensional...
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Management of hyperglycaemia in type 2 diabetes, 2022. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
The American Diabetes Association and the European Association for the Study of Diabetes convened a panel to update the previous consensus statements...
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One hundred years of insulin therapy
At the time of its first clinical application 100 years ago, insulin was presented as the cure for people with diabetes mellitus. That transpired to...
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The severity and duration of Hypoglycemia affect platelet-derived protein responses in Caucasians
ObjectiveSevere hypoglycemia is associated with increased cardiovascular death risk, and platelet responses to hypoglycemia (hypo) have been...
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Hypoglycemia in Pregnancies Following Gastric Bypass—a Systematic Review and Meta-analysis
The aims of this systematic review were to identify the prevalence of hypoglycemia among pregnant women treated with gastric bypass, and risk factors...
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Fotagliptin monotherapy with alogliptin as an active comparator in patients with uncontrolled type 2 diabetes mellitus: a randomized, multicenter, double-blind, placebo-controlled, phase 3 trial
BackgroundDipeptidyl peptidase-4 inhibitors (DPP-4i) have become firmly established in treatment algorithms and national guidelines for improving...
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Efficacy and safety of combination of empagliflozin and metformin with combination of sitagliptin and metformin during Ramadan: an observational study
BackgroundManagement of diabetes during fasting is a clinical challenge. Sodium glucose co-transporter -2 inhibitors (SGLT2i) are considered safe...
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Cost Analysis of FreeStyle Libre® 2 System in Type 2 Diabetes Mellitus Population
IntroductionFreeStyle Libre ® 2 system is a sensor-based flash-monitoring system that measures interstitial fluid glucose. The study aimed to...
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Epidemiology of hypoglycaemic episodes leading to hospitalisations in Denmark in 1998–2018
Aims/hypothesisWe aimed to investigate the nationwide trends in incidence and associated risk factors, with focus on blood glucose-lowering...
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Cost-Effectiveness of Hybrid Closed Loop Insulin Pumps Versus Multiple Daily Injections Plus Intermittently Scanned Glucose Monitoring in People With Type 1 Diabetes in The Netherlands
IntroductionHybrid closed loop (HCL) insulin pump systems and intermittently scanned continuous glucose monitoring (IS-CGM) are increasingly used by...
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Gender-specific association of biochemical variables with depression: a population-based case-control study from North India
BackgroundDepression is a highly prevalent mental disorder with complex aetiology. An emerging body of evidence shows that depression tends to...
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Long-Term Safety and Efficacy of Teneligliptin in Elderly Patients with Type 2 Diabetes: Subgroup Analysis of a 3-Year Post-Marketing Surveillance in Japan
IntroductionTeneligliptin, a dipeptidyl peptidase 4 inhibitor, was approved for the treatment of type 2 diabetes mellitus (T2DM) in Japan in 2012....
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Impaired hypoglycaemia awareness in type 1 diabetes: lessons from the lab
Hypoglycaemia remains the most common metabolic adverse effect of insulin and sulfonylurea therapy in diabetes. Repeated exposure to hypoglycaemia...