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Obstetric-related lower back pain: the effect of number of pregnancy on development of chronic lower back pain, worsening of lumbar disc degeneration and alteration of lumbar sagittal balance
ObjectiveThis study aims to determine whether the number of pregnancies contributes to the development of chronic lower back pain, worsening the...
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Real-World Economic Burden Among Patients With And Without Heart Failure Worsening After Cardiac Resynchronization Therapy
IntroductionAlthough cardiac resynchronization therapy (CRT) has the potential to improve cardiac function in patients with heart failure (HF), a...
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The worsening effect of paroxysmal atrial fibrillation on left ventricular function and deformation in type 2 diabetes mellitus patients: a 3.0 T cardiovascular magnetic resonance feature tracking study
BackgroundAtrial fibrillation (AF) has been linked to an increased risk of cardiovascular death, overall mortality and heart failure in patients with...
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Admission free-fatty acid level is a predictor of the mid-term worsening renal function in patients with ST-segment elevation myocardial infarction
Whether free fatty acids (FFAs), which are generators of reactive oxygen species and substrates of cytotoxic lipid peroxidation products in proximal...
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The worsening effect of anemia on left ventricular function and global strain in type 2 diabetes mellitus patients: a 3.0 T CMR feature tracking study
ObjectiveTo explore the additive effects of anemia on left ventricular (LV) global strains in patients with type 2 diabetes mellitus (T2DM) with or...
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Prognostic ability of mid-term worsening renal function after percutaneous coronary intervention: findings from the SHINANO registry
Chronic kidney disease is a prognostic factor for cardiovascular disease. Worsening renal function (WRF), specifically, is an important predictor of...
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Kneeling as a risk factor of patellofemoral joint cartilage damage worsening: an exploratory analysis on the Osteoarthritis Initiative
ObjectivesTo determine whether kneeling activity is associated with the MRI measures of patellofemoral (PF) joint cartilage damage worsening in...
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Use of Pregabalin and Worsening Heart Failure: A Nationwide Cohort Study
IntroductionConcerns regarding the increased risk of worsening heart failure with pregabalin have been raised. We assessed the association between...
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Changes in breakfast and water consumption among adolescents in Canada: examining the impact of COVID-19 in worsening inequity
BackgroundTo assess whether changes in breakfast and water consumption during the first full school year after the emergence of the COVID-19 pandemic...
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Relationship between self-reported visual impairment and worsening frailty transition states in older people: a longitudinal study
BackgroundVisual impairment (VI) may lead to worsening functional status and disability. Although disability is very difficult to reverse, it is...
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Increases in BMI contribute to worsening inflammatory biomarkers related to breast cancer risk in women: a longitudinal study
BackgroundInflammatory adipokines and cytokines play a pivotal role in linking obesity and breast cancer (BC) risk in women. We investigated the...
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A matter of atrophy: differential impact of brain and spine damage on disability worsening in multiple sclerosis
As atrophy represents the most relevant driver of progression in multiple sclerosis (MS), we investigated the impact of different patterns of brain...
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Worsening or improving hypoalbuminemia during continuous renal replacement therapy is predictive of patient outcome: a single-center retrospective study
BackgroundHypoalbuminemia at the initiation of continuous renal replacement therapy (CRRT) is a risk factor for poor patient outcomes. However, it is...
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Budget Impact Analysis of Vericiguat for the Treatment of Chronic Heart Failure with Reduced Ejection Fraction Following a Worsening Event
IntroductionIn the USA, patients with chronic heart failure (HF) with reduced ejection fraction (HFrEF) following a worsening HF event (WHFE) have...
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Clinical and Economic Burden of Chronic Heart Failure and Reduced Ejection Fraction Following a Worsening Heart Failure Event
IntroductionA worsening heart failure event (WHFE) is defined as progressively escalating heart failure signs/symptoms requiring intravenous diuretic...
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Risk factors for worsening sexual function after lumbar spine surgery and characteristics of non-responders to the questionnaire of sex life
PurposeTo precisely assess the Oswestry Disability Questionnaire (ODQ) and its total score (Oswestry Disability Index: ODI) and reveal...
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Confirmed 6-Month Disability Improvement and Worsening Correlate with Long-term Disability Outcomes in Alemtuzumab-Treated Patients with Multiple Sclerosis: Post Hoc Analysis of the CARE-MS Studies
IntroductionIn the 2-year CARE-MS trials (NCT00530348; NCT00548405) in patients with relapsing–remitting multiple sclerosis, alemtuzumab showed...
