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Empyema caused by Streptococcus constellatus in a patient infected with HIV: a case report and literature review
BackgroundEmpyema caused by Streptococcus constellatus (S. constellatus) is rare in patients with HIV. To analyze the clinical data of a patient...
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Plasma levels of soluble urokinase plasminogen activator receptor (suPAR) and high-sensitivity C-reactive protein after Roux-en-Y gastric bypass or sleeve gastrectomy: a 1-year prospective observational study
PurposeLow-grade inflammation in obesity contributes to the development of cardiovascular disease, diabetes mellitus and cancer, and is associated...
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Effectiveness of systemic thrombolysis on clinical outcomes in high-risk pulmonary embolism patients with venoarterial extracorporeal membrane oxygenation: a nationwide inpatient database study
BackgroundCurrent guidelines recommend systemic thrombolysis as the first-line reperfusion treatment for patients with high-risk pulmonary embolism...
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The Role of Coagulation in Heart Failure: A Literature Review
Purpose of ReviewThis article summarizes the role of coagulation factors in the pathophysiology of heart failure including D-dimer, fibrinogen and...
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Enhanced Expression of Plasminogen Activators and Inhibitor in the Healing of Tympanic Membrane Perforation in Rats
The significance of plasminogen activation during the tympanic membrane (TM) healing is known mainly from studies performed on knock-out mice. In the...
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What is circulating factor disease and how is it currently explained?
Nephrotic syndrome (NS) consists of the clinical triad of hypoalbuminaemia, high levels of proteinuria and oedema, and describes a heterogeneous...
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Tension pyopneumothorax caused by Parvimonas micra: a case report
Tension pyopneumothorax is a rare and life-threatening complication of pneumonia, lung abscess, and empyema, and immediate thoracic drainage or...
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Transitions of blood immune endotypes and improved outcome by anakinra in COVID-19 pneumonia: an analysis of the SAVE-MORE randomized controlled trial
BackgroundEndotype classification may guide immunomodulatory management of patients with bacterial and viral sepsis. We aimed to identify immune...
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Successful recanalization of completely obstructed portal vein thrombosis after right hepatectomy for perihilar cholangiocarcinoma by aspiration thrombectomy via the ileocolic mesenteric vein and subsequent systemic anticoagulation with edoxaban
Portal vein thrombosis (PVT) is a lethal complication of hepatectomy if not properly treated. An 81-year-old woman diagnosed with postoperative PVT...
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Soluble urokinase-type plasminogen activator receptor represents exercise tolerance and predicts adverse cardiac events in patients with heart failure
Soluble urokinase-type plasminogen activator receptor (suPAR) is a membrane-binding protein that is released into the blood stream by immune...
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suPARnostic: an advanced predictive tool for detecting recurrence in renal cell carcinoma
BackgroundPlasma soluble urokinase-type Plasminogen Activator Receptor (suPAR) predicts disease aggressiveness in renal cell carcinoma (ccRCC), but...
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Predictive value of suPAR in AKI: a systematic review and meta-analysis
BackgroundSome clinical trials have shown that soluble urokinase-type plasminogen activator receptor (suPAR) has good predictive value for acute...
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Data-Driven Identification of Targets for Fluorescence-Guided Surgery in Non-Small Cell Lung Cancer
PurposeIntraoperative identification of lung tumors can be challenging. Tumor-targeted fluorescence-guided surgery can provide surgeons with a tool...
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The Plasminogen Activator System, Glucocorticoid, and Mineralocorticoid Receptors in the Primate Endometrium During Artificial Menstrual Cycles
As a key mechanism in fibrinolysis and tissue remodeling, the plasminogen activator system has been suggested in the process of endometrial shedding...
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Plasminogen activator inhibitor 1 and gestational diabetes: the causal relationship
Plasminogen activator inhibitor 1 (PAI-1) also known as serpin E1 or endothelial plasminogen activator inhibitor, is produced from endothelial cells...
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The diagnostic value of soluble urokinase-type plasminogen activator receptor (suPAR) for the discrimination of vertebral osteomyelitis and degenerative diseases of the spine
BackgroundThere is still a challenge in discriminating between vertebral osteomyelitis and degenerative diseases of the spine. To this end, we...
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Rationale and design of the Japanese Biomarkers in Nephrotic Syndrome (J-MARINE) study
IntroductionDisease subty** and monitoring are essential for the management of nephrotic syndrome (NS). Although various biomarkers for NS have...
