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Differentiation of autoimmune pancreatitis from pancreatic adenocarcinoma using CT characteristics: a systematic review and meta-analysis
ObjectivesTo determine informational CT findings for distinguishing autoimmune pancreatitis (AIP) from pancreatic ductal adenocarcinoma (PDAC) and to...
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Genetic findings of Sanger and nanopore single-molecule sequencing in patients with X-linked hearing loss and incomplete partition type III
BackgroundPOU3F4 is the causative gene for X-linked deafness-2 (DFNX2), characterized by incomplete partition type III (IP-III) malformation of the...
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Spatially distinct molecular patterns of gene expression in idiopathic pulmonary fibrosis
BackgroundIdiopathic pulmonary fibrosis (IPF) is a heterogeneous disease that is pathologically characterized by areas of normal-appearing lung...
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Hereditary thrombocythemia due to splicing donor site mutation of THPO in a Japanese family
Thrombopoietin (THPO) is an essential factor for platelet production. Hereditary thrombocythemia (HT) is caused by a germline mutation of THPO , MPL ,...
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Food Insecurity and Engagement in Transactional Sex Among Female Secondary Students in Rwanda
The relationship between food insecurity and transactional sex is well recognized, but less is known about this relationship among adolescents. We...
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Long-range and real-time PCR identification of a large SERPINC1 deletion in a patient with antithrombin deficiency
Congenital antithrombin (AT) or serpin C1 deficiency, caused by a SERPINC1 abnormality, is a high-risk factor for venous thrombosis. SERPINC1 is...
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Anatomy of the vitelline vein remnant in human embryos and fetuses
PurposeTo demonstrate the entire course of the human vitelline vein (VV) in specimens after degeneration of the yolk sac.
MethodsSagittal and...
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Comprehensive and Integrated Services in Specialty Mental Health Treatment Facilities in the US: Differences by the Racial/Ethnic Composition of the Facility’s Clientele, 2020
The integration of multiple ancillary services into mental health treatment settings may improve outcomes, but there are no national studies...
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SIRT1 mediates breast cancer development and tumorigenesis controlled by estrogen-related receptor β
Silent mating type information regulation 2 homolog 1 (SIRT1) is a class III histone deacetylase (HDAC) that is NAD + dependent and essential for...
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GALNT2 targeted by miR-139-5p promotes proliferation of clear cell renal cell carcinoma via inhibition of LATS2 activation
Polypeptide N -Acetylgalactosaminyltransferase (GALNTs) are critical enzymes that initiate mucin type-O glycosylation, and are closely associated with...
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Analysis and Validation of TMED3 correlates with poor prognosis and tumor immune infiltration of glioma
BackgroundGlioma is the most common primary intracranial tumor. It is notorious for its high degree of malignancy, strong invasion, and poor...
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Policy actors’ perceptions of public participation to tackle health inequalities in Scotland: a paradox?
BackgroundHealth inequalities are persistent and widening with transformative policy change needed. Radically shifting policy to tackle upstream...
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The kisspeptin system in and beyond reproduction: exploring intricate pathways and potential links between endometriosis and polycystic ovary syndrome
Endometriosis and polycystic ovary syndrome (PCOS) are two common female reproductive disorders with a significant impact on the health and quality...
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Computed tomography enterography predicts surgical-free survival in symptomatic stricturing Crohn’s disease
ObjectivesThe study aimed to predict surgical risks for patients with symptomatic stricturing Crohn’s disease (CD) using computed tomography...
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Biological determinants of PSMA expression, regulation and heterogeneity in prostate cancer
Prostate-specific membrane antigen (PSMA) is an important cell-surface imaging biomarker and therapeutic target in prostate cancer. The PSMA-targeted...
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Evaluating local primary health care actions to address health inequities: analysis of Australia’s Primary Health Networks
BackgroundMeso-level, regional primary health care organisations such as Australia’s Primary Health Networks (PHNs) are well placed to address health...
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Bioinformatics-based analysis of potential candidates chromatin regulators for immune infiltration in osteoarthritis
BackgroundThrough the bioinformatics analysis to screen out the potential chromatin regulators (CRs) under the immune infiltration of osteoarthritis...
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Sustainable political commitment is necessary for institutionalizing community participation in health policy-making: Insights from Iran
BackgroundCommunity participation is currently utilized as a national strategy to promote public health and mitigate health inequalities across the...
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The RORɣ/SREBP2 pathway is a master regulator of cholesterol metabolism and serves as potential therapeutic target in t(4;11) leukemia
Dysregulated cholesterol homeostasis promotes tumorigenesis and progression. Therefore, metabolic reprogramming constitutes a new hallmark of cancer....
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Kawasaki disease OX40–OX40L axis acts as an upstream regulator of NFAT signaling pathway
BackgroundWe investigated a costimulatory molecule OX40–OX40L acting as an upstream regulator to regulate the nuclear factor of activated T cell...
