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Robotic Versus Open Hepatic Arterial Infusion Pump Placement for Unresectable Intrahepatic Cholangiocarcinoma
BackgroundHepatic arterial infusion pump (HAIP) chemotherapy is an effective treatment for patients with unresectable intrahepatic cholangiocarcinoma...
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Repeated hepatic resection for colorectal liver metastases: is this concept safe and feasible?
BackgroundThe beneficial outcomes of hepatectomy in patients with colorectal metastases have encouraged the attempts of repeated hepatectomy in...
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Rescue percutaneous transhepatic portal vein embolization after failed associated liver partition and portal vein ligation for staged hepatectomy in a patient with multiple liver metastases of rectal cancer: a case report
BackgroundLiver metastasis is the most common form of distant spread of colorectal cancer. Despite oncological and surgical advances, only about 25%...
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Role of stereotactic body radiotherapy in multidisciplinary management of liver metastases in patients with colorectal cancer
In the treatment of colorectal cancer patients with distant metastases, the development of new anticancer agents has considerably prolonged...
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Missing colorectal liver metastases: the surgical challenge
BackgroundNew chemotherapy schemes have allowed for a better radiological response of unresectable colorectal liver metastases, leading to an...
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A Model to Predict Treatment Failure in Patients Undergoing Upfront Surgery for Resectable Colorectal Liver Metastases
IntroductionPatients who recur in the first year after resection of colorectal liver metastases (CRLM) do poorly. The aim of our study was to predict...
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Neoadjuvant chemotherapy weakens the prognostic value of the pathological tumor burden score for colorectal cancer liver metastases
BackgroundThe pathological tumor burden score (TBS) has been proven to be a better risk stratification tool for liver metastasis of colorectal cancer...
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Liver metastases in pancreatic ductal adenocarcinoma: a predictive model based on CT texture analysis
PurposeTo develop a predictive model for liver metastases in patients with pancreatic ductal adenocarcinoma (PDAC) based on textural features of the...
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Efficacy and Safety of the Melphalan/Hepatic Delivery System in Patients with Unresectable Metastatic Uveal Melanoma: Results from an Open-Label, Single-Arm, Multicenter Phase 3 Study
BackgroundUveal melanoma (UM) has a poor prognosis once liver metastases occur. The melphalan/Hepatic Delivery System (melphalan/HDS) is a...
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A CT-based radiomics nomogram for predicting histopathologic growth patterns of colorectal liver metastases
PurposeTo develop a computed tomography (CT)-based radiomics nomogram for pre-treatment prediction of histopathologic growth patterns (HGPs) in...
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Impact of preoperative chemotherapy on perioperative morbidity in combined resection of colon cancer and liver metastases
BackgroundPreoperative chemotherapy, or neoadjuvant therapy (NAC) can be used to improve resectability but can also have hepatotoxic effects on the...
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Prognostic role of infracentimetric colorectal liver metastases
BackgroundThe number of lesions and the size of the largest (CRLMmax) have been widely investigated as prognostic factors in patients with colorectal...
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Development and validation of a nomogram to predict which patients with colorectal cancer liver metastases would benefit from primary tumor resection
PurposeThe use of primary tumor resection (PTR) in the treatment of colorectal cancer liver metastases (CRLM) patients has become increasingly...
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Liquid Biopsy by ctDNA in Liver Transplantation for Colorectal Cancer Liver Metastasis
IntroductionColorectal cancer is a leading cause of cancer-related death worldwide. Metastatic liver disease develops in 50% of cases and drives...
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Prognosis of a Heterogeneous TRG Pathological Response to Neoadjuvant Chemotherapy in Patients who Undergo Resection for Colorectal Liver Metastases
BackgroundOptimal management of colorectal liver metastasis (CRLM) is based on a combination of chemotherapy and surgical resection. The tumor...
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Efficacy of treatment based on TKIs in combination with PD-1 inhibitors for unresectable recurrent hepatocellular carcinoma
Background and objectiveThe recurrence occurs within 5 years in up to 70% of hepatocellular carcinoma (HCC) patients who received radical liver...
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Combining Radiofrequency Ablation with Hepatic Resection for Liver-Only Colorectal Metastases: A Propensity-Score Based Analysis of Long-Term Outcomes
BackgroundCombining liver resection (LR) with radiofrequency ablation (RFA) is nowadays an accepted option for treating colorectal liver metastases...
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Is Surgical Treatment Effective or Contraindicated in Patients with Colorectal Cancer Liver Metastases Exhibiting Extrahepatic Metastasis?
BackgroundSurgical resection for patients with hepatic and extrahepatic colorectal metastases remains controversial. This study aimed to determine...
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Survival after combined resection and ablation is not inferior to that after resection alone, in patients with four or more colorectal liver metastases
PurposeColorectal liver metastases (CRLM) are the predominant factor limiting survival in patients with colorectal cancer. Multimodal treatment...
