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Intravenous thrombolysis for acute ischemic stroke during two COVID-19 outbreaks in China: Wuhan pandemic and Bei**g pandemic
IntroductionThe COVID-19 pandemic has had an impact on the emergency department (ED). Door-to-needle time (DNT) could be prolonged for intravenous...
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Metal ion chelation enhances tissue plasminogen activator (tPA)-induced thrombolysis: an in vitro and in vivo study
Stroke is the third leading cause of death in the United States and the leading cause of adult disability. Despite enormous research efforts...
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Single-center experience with catheter-directed thrombolysis and balloon angioplasty for acute upper-extremity deep vein thrombosis: a case series study
BackgroundEffective treatment of upper extremity deep vein thrombosis (UEDVT) is crucial to prevent further complications. Various treatments,...
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Hypoperfusion index ratio and pretreatment with intravenous thrombolysis are independent predictors of good functional outcome in acute ischemic stroke patients with large vessel occlusion treated with acute reperfusion therapies
IntroductionWe aimed to investigate the performance of several neuroimaging markers provided by perfusion imaging of Acute Ischemic Stroke (AIS)...
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Acute Stroke Treatment in an Anticoagulated Patient: When Is Thrombolysis an Option?
Purpose of ReviewDirect oral anticoagulants (DOACs: the factor Xa inhibitors rivaroxaban, apixaban, and edoxaban and the direct thrombin inhibitor...
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Catheter directed compared to systemically delivered thrombolysis for pulmonary embolism: a systematic review and meta-analysis
To compare the efficacy and safety of systemic and catheter directed thrombolysis for patients with pulmonary embolism. Pubmed and Cochrane Central...
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Safety and efficacy of intravenous thrombolysis in patients with acute ischemic stroke taking direct oral anticoagulants prior to stroke: a meta-analysis
BackgroundTo assess the safety and efficacy of intravenous thrombolysis (IVT) in patients with acute ischemic stroke (AIS) taking direct oral...
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Utilization trends and outcomes of catheter-directed thrombolysis for pulmonary embolism in the US by race/ethnicity
Contemporary data on catheter-directed thrombolysis (CDT) utilization trends and associated hospital outcomes in pulmonary embolism (PE) n the US is...
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Sex Differences in Outcomes of Intravenous Thrombolysis in Acute Ischemic Stroke Patients with Preadmission Use of Antiplatelets
AimTo compare safety and functional outcomes of intravenous thrombolysis (IVT) between females and males with acute ischaemic stroke (AIS) in...
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Large thrombosed portomesenteric venous aneurysm treated with pharmacomechanical thrombolysis combined with TIPS placement
BackgroundAneurysms are rare anomalies of the portomesenteric venous system. Thrombotic complications of these lesions can lead to mesenteric venous...
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Direct Endovascular Thrombectomy Alone vs. Bridging Thrombolysis for Patients with Acute Ischemic Stroke
PurposeAlthough the current guidelines recommend bridging thrombolysis (BT) therapy, which is intravenous thrombolysis (IVT) followed by endovascular...
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Ultrasound-accelerated thrombolysis in high-risk perioperative pulmonary embolism: two case reports and review of literature
IntroductionTreatment of high-risk pulmonary embolism (PE) in perioperative patients remains challenging. Systemic thrombolysis is associated with a...
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Outcomes of stroke patients undergoing thrombolysis in Sri Lanka; an observational prospective study from a low-middle income country
BackgroundStroke related deaths are relatively higher in low- and middle-income countries where only a fraction of eligible patients undergo...
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The metabolic score for insulin resistance as a predictor of clinical outcome in stroke patients treated by intravenous thrombolysis
Background and purposeInsulin resistance is associated with clinical outcomes among patients with ischemic stroke. We aimed to investigate the...
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Long-term functional outcome and quality of life 2.5 years after thrombolysis in acute ischemic stroke
BackgroundEvaluation of outcome after stroke is largely based on assessment of gross function 3 months after stroke onset using scales such as mRS....
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Evaluation of a prehospital endovascular therapy stroke bypass program
IntroductionPrehospital stroke endovascular therapy bypass transports patients with suspected large vessel occlusion directly to an endovascular...
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Efficacy and safety of intra-arterial thrombolysis in patients with central retinal artery occlusion: a systematic review and meta-analysis
PurposeTo investigate the efficacy and safety of intra-arterial thrombolysis (IAT) in patients with central retinal artery occlusion (CRAO).
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Clinical impact of assessing thrombus age using magnetic resonance venography prior to catheter-directed thrombolysis
ObjectivesMagnetic resonance venography (MRV) is underutilized in the evaluation of thrombus properties prior to endovascular treatment but may...
