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Curcumol inhibits EMCV replication by activating CH25H and inhibiting the formation of ROs
BackgroundZedoary turmeric oil extracted from the roots of curcuma ( Curcuma aeruginosa Roxb.) is used for the treatment of myocarditis in China....
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Nano-chitosan/bovine lactoperoxidase and lactoferrin formulation modulates the hepatic deterioration induced by 7,12-dimethylbenz[a]anthracene
Lactoperoxidase (LPO) and lactoferrin (LF) are promising bovine proteins that can be nano-formulated with chitosan nanoparticles giving a potent...
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Plasma exosomal protein PLG and SERPINA1 in colorectal cancer diagnosis and coagulation abnormalities
PurposeEarly diagnosis of colorectal cancer (CRC) is critical to patient prognosis; however, there is lack of non-invasive biomarkers that are...
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Completion total mesorectal excision following transanal endoscopic microsurgery does not compromise outcomes in patients with rectal cancer
BackgroundTransanal endoscopic microsurgery (TEM) represents a choice of treatment in patients with neoplastic lesions in the rectum. When TEM fails,...
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Exosomal AFAP1-AS1 binds to microRNA-15a-5p to promote the proliferation, migration, and invasion of ectopic endometrial stromal cells in endometriosis
BackgroundEndometriosis (EMS) remains a major challenge to reproductive health due to multifactorial etiology, disease heterogeneity, and the lack of...
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Synthesis and characterization of poly (styrene-co-acrylamide)-graft-polyanilines as new sorbents for mercuric present in aqueous hydrocarbon liquids
BackgroundThe unprocessing hydrocarbon oil often contains high concentrations of mercury, which damages the metallic processing components and have...
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Increased frequency of proangiogenic tunica intima endothelial kinase 2 (Tie2) expressing monocytes in individuals with type 2 diabetes mellitus
BackgroundIndividuals with type 2 diabetes mellitus (T2DM) have an increased risk for develo** macrovascular disease (MVD) manifested by...
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Endometrial stem cells alleviate cisplatin-induced ferroptosis of granulosa cells by regulating Nrf2 expression
BackgroundPremature ovarian failure (POF) caused by cisplatin is a severe and intractable sequela for young women with cancer who received...
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Acquisition and carriage of genetically diverse multi-drug resistant gram-negative bacilli in hospitalised newborns in The Gambia
BackgroundThis detailed genomic study characterised multi-drug resistant-Gram negative bacilli (MDR-GNB) carriage in neonates < 2 kg and paired...
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Plasmid mediated penicillin and tetracycline resistance among Neisseria gonorrhoeae isolates from Kenya
BackgroundTreatment of gonorrhea is complicated by the development of antimicrobial resistance in Neisseria gonorrhoeae (GC) to the antibiotics...
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Transanal endoscopic microsurgery with alternative neoadjuvant imatinib for localized rectal gastrointestinal stromal tumor: a single center experience with long-term surveillance
BackgroundTransanal endoscopic microsurgery (TEM) is widely used in the treatment of local rectal lesions and helps avoid radical surgery. This study...
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Centriolar defects, centrin 1 alterations, and FISH studies in human spermatozoa of a male partner of a couple that produces aneuploid embryos in natural and artificial fertilization
PurposeTo study the potential paternal contribution to aneuploidies in the man of a couple who obtained trisomic embryos with natural and assisted...
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Chromosomal studies on drug resistance genes in extended spectrum β-lactamases producing-Klebsiella pneumoniae isolated from equine
BackgroundK . pneumoniae is one of the most virulent and multidrug resistant bacteria, of great concern in both human and veterinary medicine....
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Mitochondrial content, activity, and morphology in prepubertal and adult human ovaries
PurposeTo investigate whether mitochondrial content, activity, and morphology differ in prepubertal versus adult ovarian follicles.
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Hypoxic lung cancer cell-derived exosomal miR-21 mediates macrophage M2 polarization and promotes cancer cell proliferation through targeting IRF1
BackgroundHypoxia is the hallmark of the tumor microenvironment (TME) and plays a critical role during the progress of tumor development. A variety...
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Silver nanoparticles and Chlorella treatments induced glucosinolates and kaempferol key biosynthetic genes in Eruca sativa
BackgroundMicroalgae and nanoparticles are currently considered promising tools for numerous agricultural and biotechnological applications. The...
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Three-dimensional electron microscopy for endothelial glycocalyx observation using Alcian blue with silver enhancement
Glycocalyx (GCX) is a thin layer of negatively charged glycoproteins that covers the vascular endothelial surface and regulates various biological...
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Reliability of Stereophotogrammetry for Area Measurement in the Periocular Region
Three-dimensional (3D) stereophotography area measurements are essential for describing morphology in the periocular region. However, its reliability...
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Detection of plasma exosomal miRNA-205 as a biomarker for early diagnosis and an adjuvant indicator of ovarian cancer staging
BackgroundOvarian cancer (OC) is one of the serious threats to the health of women worldwide, and accurate biomarkers are urgently demanded for early...
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Characterisation of and risk factors for extended-spectrum β-lactamase producing Enterobacterales (ESBL-E) in an equine hospital with a special reference to an outbreak caused by Klebsiella pneumoniae ST307:CTX-M-1
BackgroundExtended-spectrum β-lactamase producing Enterobacterales (ESBL-E) are important causative agents for infections in humans and animals. At...