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Genetik von Bewegungsstörungen – selten aber wichtig
Rare genetic movement disorders are a heterogeneous group of diseases. The causes of many of these rare movement disorders could be resolved due to...
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Tauopathien
BackgroundThe microtubule-associated tau protein is the defining denominator of a group of neurodegenerative diseases termed tauopathies.
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Neue Therapieansätze bei der Parkinson-Erkrankung
Over the last years major advances have been made in the identification of specific pathways underlying the pathophysiology of subgroups of patients...
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Hilfreiche Zusatzuntersuchungen beim idiopathischen Parkinson-Syndrom
BackgroundThe clinical diagnosis of idiopathic Parkinson’s disease (iPD) can be challenging. In these cases, additional diagnostic methods are...
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Genetische Risikovarianten beim Parkinson-Syndrom und anderen Bewegungsstörungen
Movement disorders are often genetically complex with genetic risk factors playing a major role. For example, monogenic causes of Parkinson’s disease...
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Anforderungen des Neurologen an Obduktionen
BackgroundIn assuring the quality of the healthcare system, it is the intention of healthcare politics to raise the number of clinical autopsies.
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Zellersatz und adulte Neurogenese beim idiopathischen Parkinson-Syndrom
Parkinson’s disease (PD) is the most common age-related movement disorder and characterized by slowly progressive neurodegeneration resulting in...
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Pathomechanismen und klinische Aspekte der frontotemporalen Lobärdegeneration
BackgroundFrontotemporal lobar degeneration (FTLD) includes a spectrum of heterogeneous clinical and neuropathological diseases. In a strict sense...
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Diagnostik des klinischen und prodromalen idiopathischen Parkinson-Syndroms
BackgroundRecently, the Movement Disorder Society (MDS) published an adaptation of the previous United Kingdom Brain Bank Society (UKBBS) criteria...
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Epidemiologie und Ursachen der Parkinson-Erkrankung
Parkinson’s disease (PD) is the second most common neurodegenerative disease and has a growing socioeconomic impact due to demographic changes in the...
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Schlaf und neurologische Erkrankungen
Knowledge of the physiology of sleep-wake regulation can contribute to an understanding of the pathophysiology and symptoms of neurological diseases...
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Biochemische Grundlagenprozesse im Verlauf der Glaukomerkrankung
The term glaucoma summarizes a group of eye diseases that are accompanied by impairments of the optic nerve and related visual field deficits. An...
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Schlafstörungen bei Demenzkranken
Dementia is characterized by cognitive and also behavioral and psychological symptoms of dementia (BPSD). The most prominent BPSD are depression and...
