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Household air pollution from solid fuel use and depression among adults in rural China: evidence from the China Kadoorie Biobank data
BackgroundSolid fuels are still widely used for cooking in rural China, leading to various health implications. Yet, studies on household air...
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The promise and challenges of combination therapies with antibody-drug conjugates in solid tumors
Antibody-drug conjugates (ADCs) represent an important class of cancer therapies that have revolutionized the treatment paradigm of solid tumors. To...
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Bcl-2 pathway inhibition in solid tumors: a review of clinical trials
Due to their key role in the pathogenesis of cancer through the regulation of apoptosis, the B-cell leukemia/lymphoma-2 (BCL-2) family proteins have...
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Long non-coding RNAs: controversial roles in drug resistance of solid tumors mediated by autophagy
Current genome-wide studies have indicated that a great number of long non-coding RNAs (lncRNAs) are transcribed from the human genome and appeared...
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Association between Household Solid Fuel Use and Sarcopenia Risk among Middle-Aged and Older Adults in China: A Nationwide Population-Based Cohort Study
BackgroundsHousehold solid fuel have been associated with changes of handgrip strength, and exposure to ambient air pollution might be one risk...
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Prediction of histologic types in solid lung lesions using preoperative contrast-enhanced CT
ObjectivesThis study aimed to develop and validate a predicting model for the histologic classification of solid lung lesions based on preoperative...
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Financial inclusion and households’ choice of solid waste disposal in Ghana
BackgroundAs the amount of solid waste generated by households in Ghana continues to grow, policy makers are preoccupied with finding better means of...
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Clinical research progress of callisperes® of drug-loaded microsphere arterial chemoembolisation in the treatment of solid tumors
The incidence and mortality of cancer is ever-increasing, which poses a significant challengesto human health and a substantial economic burden to...
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Pharmacokinetics, safety, and antitumor activity of talazoparib monotherapy in Chinese patients with advanced solid tumors
Talazoparib, a poly(ADP-ribose) polymerase inhibitor, has demonstrated efficacy in the treatment of advanced breast and prostate cancers in Western...
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Clinical evidence for efficacy of pembrolizumab in MSI-H and TMB-H advanced solid tumor: results from three cancer centers in China
BackgroundPembrolizumab has been indicated in the treatment of solid tumors with high frequency microsatellite instability (MSI-H) or high tumor...
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Surgical Management of Solid Pseudopapillary Neoplasm of the Pancreas—an Experience from Tertiary Care Centre
Solid pseudopapillary neoplasm (SPN) is uncommon and constitutes to 1–2% of pancreatic tumours. Owing to its rarity, literature is sparse on its...
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Causes of endoscopic misdiagnosis of gastrointestinal cyst as solid lesion
BackgroundTo explore the causes of endoscopic misdiagnosis of gastrointestinal cyst as solid lesion and the diagnostic value and limitations of EUS,...
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Infiltrative solid papillary carcinoma of the breast with axillary lymph node metastasis: a case report
BackgroundSolid papillary carcinoma (SPC) is a rare breast papillary tumor variant. The main histological features of SPC consist of neoplastic...
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Incidence of renal cell carcinoma after solid organ transplantation: a systematic review and meta-analysis
BackgroundThe incidence rate of malignant tumors after solid organ transplantation is higher than the normal population. The aim of our study is to...
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Mesothelin-targeted CAR-T therapy combined with irinotecan for the treatment of solid cancer
BackgroundChimeric antigen receptor (CAR) T cell therapy has shown promising results in treating blood cancers, but it has limited efficacy against...
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Characterization, cellular uptake in Caco-2 cells and physiologically based pharmacokinetic modeling of baicalin-loaded solid lipid nanoparticles
BackgroundBaicalin is a natural compound having intriguing and useful pharmacological properties that may be used alone or in conjunction with other...
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The effects of fine particulate matter, solid fuel use and greenness on the risks of diabetes in middle-aged and older Chinese
BackgroundPrevious studies provided clues that environmental factors were closely related to diabetes incidence. However, the evidence from...
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TCR engineered T cells for solid tumor immunotherapy
T cell immunotherapy remains an attractive approach for cancer immunotherapy. T cell immunotherapy mainly employs chimeric antigen receptor (CAR)-...
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Solid tumours showing oligoprogression to immune checkpoint inhibitors have the potential for abscopal effects
PurposeGiven the uncertainty surrounding the abscopal effect (AE), it is imperative to identify promising treatment targets. In this study, we aimed...
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Distinct impacts of radiological appearance on lymph node metastasis and prognosis based on solid size in clinical T1 non-small cell lung cancer
BackgroundSolid nodules (SN) had more aggressive features and a poorer prognosis than part-solid nodules (PSN). This study aimed to evaluate the...
