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Circular RNA as new serum metabolic biomarkers in patients with premature ovarian insufficiency
ObjectiveQuantitative real-time PCR (qPCR) is used to detect the differential expression of circular RNAs in patients of premature ovarian...
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Changes of biochemical biomarkers in the serum of children with convulsion status epilepticus: a prospective study
BackgroundConvulsive status epilepticus (CSE) is a common neurologic emergency with high morbidity and mortality. This single center study is aimed...
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Decoding the genetic links between serum lipidomic profile, amino acid biomarkers, and programmed cell death protein-1/programmed cell death-ligand-1
BackgroundDisruptions in lipid metabolism and amino acids have been increasingly linked to resistance to immunotherapy. However, the underlying...
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Recent Advances in Serum Biomarkers for Risk Stratification and Patient Management in Cardio-Oncology
Purpose of ReviewFollowing significant advancements in cancer therapeutics and survival, the risk of cancer therapy-related cardiotoxicity (CTRC) is...
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Urate-lowering therapy, serum urate, inflammatory biomarkers, and renal function in patients with gout following pegloticase discontinuation
Background/PurposeLittle is known about long-term clinical outcomes or urate-lowering (ULT) therapy use following pegloticase discontinuation. We...
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A serum proteomic study of two case-control cohorts identifies novel biomarkers for bipolar disorder
We set out to identify novel protein associations with potential as clinically viable biomarkers for bipolar disorder. To this end, we used proximity...
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Serum biomarkers for the assessment of muscle damage in various surgical approaches in primary total hip arthroplasty: a systematic review of comparative studies
PurposeUsing serum biomarkers, this systematic review assessed soft tissue injury following different total hip arthroplasty surgical approaches. The...
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Serum brain injury biomarkers are gestationally and post-natally regulated in non-brain injured neonates
BackgroundTo determine the association of gestational age (GA) and day of life (DOL) with the circulating serum concentration of six brain...
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Evaluation of galectin-3 and intestinal fatty acid binding protein as serum biomarkers in autosomal recessive polycystic kidney disease
BackgroundAutosomal recessive polycystic kidney disease (ARPKD) causes fibrocystic kidney disease, congenital hepatic fibrosis, and portal...
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The effects of low-fat dairy products fortified with 1500 IU vitamin D3 on serum liver function biomarkers in adults with abdominal obesity: a randomized controlled trial
IntroductionVitamin D deficiency has been reported to affect liver function biomarkers. This study was aimed to investigate the effect of consuming...
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Serum biomarkers REG1A and REG3A combined with the traditional CEA represent a novel nomogram for the screening and risk stratification of colorectal cancer
BackgroundTo develop and validate a serum protein nomogram for colorectal cancer (CRC) screening.
MethodsThe serum protein characteristics were...
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Assessment of serum and synovial fluid MMP-3 and MPO as biomarkers for psoriatic arthritis and their relation to disease activity indices
Research on biomarkers for the diagnosis and monitoring of psoriatic arthritis (PsA) is ongoing. The purpose of this study was to assess the...
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Correlation Between Serum and Fecal Biomarkers and Patient-Reported Outcomes in Patients with Crohn’s Disease and Ulcerative Colitis
BackgroundPatient-reported outcomes (PROs), such as the short CD activity index (sCDAI) and partial Mayo Score (PMS), are used to define clinical...
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Utility of serum biomarkers for predicting cancer in patients with previous negative prostate biopsy
PurposeTo review the role of serum biomarkers: prostate-specific antigen (PSA), PSA density (PSAD), free:total PSA ratio, prostate health index (PHI)...
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A Novel Approach to Predicting Early Pregnancy Outcomes Dynamically in a Prospective Cohort Using Repeated Ultrasound and Serum Biomarkers
This study aimed to develop a dynamic model for predicting outcome during the first trimester of pregnancy using baseline demographic data and...
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Association of Mediterranean diet adherence with disease progression, quality of life and physical activity, sociodemographic and anthropometric parameters, and serum biomarkers in community-dwelling older adults with multiple sclerosis: a cross-sectional study
BackgroundMultiple sclerosis (MS) constitutes a chronic inflammatory and degenerative demyelinating disease, which can progressively lead to a broad...
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Interleukin-31 and soluble CD40L: new candidate serum biomarkers that predict therapeutic response in multiple sclerosis
Multiple sclerosis (MS) is a chronic demyelinating autoimmune disease that affects the central nervous system (CNS), varying from relatively benign...
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Salivary and serum haptoglobin, adenosine deaminase, and immunoglobulin G in growing pigs
BackgroundIdentification of animals in need of medical treatment is important in porcine health management, where analytical samples applicable at...
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DIA-based proteomics analysis of serum-derived exosomal proteins as potential candidate biomarkers for intrahepatic cholestasis in pregnancy
BackgroundData-independent acquisition (DIA) is one of the most powerful and reproducible proteomic technologies for large-scale digital qualitative...
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Serum and urinary biomarkers to predict acute kidney injury in premature infants: a systematic review and meta-analysis of diagnostic accuracy
BackgroundPremature infants are at high risk for acute kidney injury (AKI) and current diagnostic criteria are flawed. The objective of this study...
