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Klassifikation von Leukämien
Acute and chronic leukemias represent heterogeneous disorders which are divided in a variety of subtypes based on morphological, immunologic, and...
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Neoadjuvant Capecitabine Combined with Standard Radiotherapy in Patients with Locally Advanced Rectal Cancer
Purpose:The objective of this expanded phase II trial was to confirm the safety results of the preceding phase I study and establish the efficacy of...
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HLA Class II Alleles and the Presence of Circulating Epstein-Barr Virus DNA in Greek Patients with Nasopharyngeal Carcinoma
Background and Purpose:Nasopharyngeal carcinoma (NPC) represents a seldom malignancy in most developed countries. Nevertheless, NPC receives an...
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Trends und neue Entwicklungen in der Diagnostik von Pilzinfektionen
Diagnosing fungal infections remains a problem, particularly in the immunocompromised patient. Symptoms are mostly non-specific and colonization is...
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Morphologie und Diagnostik der oberflächlichen und invasiven Candidiasis. Die Sicht des Pathologen
Adherence to the epithelial surface and tissue invasion represent the major steps in the pathogenesis of candida infection. Grossly, localized...
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Invasive Candidiasis beim nicht-neutropenischen kritisch kranken Patienten
Invasive candidiasis can occur in immunosuppressed patients as well as in critically ill, non-immunocompromised patients and is associated with high...
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Neue Erkenntnisse in der Diagnostik chronischer myeloproliferativer Syndrome
The Philadelphia-negative chronic myeloproliferative diseases (CMPD) are very complex and heterogeneous disorders. They are represented by...
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Entsendungseignungsuntersuchung (EEU): Definition, Empfehlungen zum Untersuchungsaufwand und Einsatz
Standards for medical clearance for private or business missions abroad are – at least in the German speaking countries – not clearly defined and...
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Pathogenese der Atherosklerose: Evaluation eines Modelles zur In-vitro-Simulation der Plaqueentstehung
For the study of the pathogenesis of atherosclerosis, different in vitro models have been developed that are based on the monoor coculture of...
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Acute acalculous cholecystitis – a rare postoperative complication following kidney transplantation
BACKGROUND: While acute cholecystitis in patients with gallstone disease is a known event after transplantation, acalculous cholecystitis...
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Aptamer-basierte Stammzelltechnologie zur Erhöhung der Hämokompatibilität
For years intensive research has been done to endothelialize vascular prostheses before implantation. However, this procedure is extremely...
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Modulation of Glucose Metabolism Inhibits Hypoxic Accumulation of Hypoxia-Inducible Factor-1α (HIF-1α)
Background and Purpose:The hypoxic accumulation of the transcription factor subunit hypoxia-inducible factor-1α (HIF-1α), a potential endogenous...
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HIV-Infektion 2007
There is hardly any other medical field that has experienced changes and developments as dramatic as in the treatment of HIV infection in the last...
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Microarray-Genexpressionsanalysen in der Leukämiediagnostik
So far, the diagnosis in leukemia is based on cytomorphology and cytochemistry, multiparameter flow cytometry, combined with cytogenetics,...
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Diagnostik, Klassifikation und Prognosefaktoren der akuten myeloischen Leukämie
Diagnostics:The continuously growing knowledge about criteria important for biology, pathogenesis, prognosis and treatment of acute myeloid leukemia...
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Die allogene Stammzelltransplantation im Therapiekonzept der akuten myeloischen Leukämie
Allogeneic stem cell transplantation (SCT) is the most powerful treatment option for acute myeloid leukemia (AML). However, SCT is also complicated...