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Real-world experience with VMAT2 inhibitors in Tourette syndrome
ObjectivesWe aimed to review our “real-world” experience with the vesicular monoamine transporter 2 (VMAT2) inhibitors tetrabenazine,...
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Real-world experience with ruxolitinib therapy for steroid-refractory acute graft versus host disease
Acute graft versus host disease (aGVHD) is a complication of allogeneic hematopoietic stem cell transplant (HCT) and is associated with significant...
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Personalized venlafaxine dose prediction using artificial intelligence technology: a retrospective analysis based on real-world data
BackgroundVenlafaxine dose regimens vary considerably between individuals, requiring personalized dosing.
AimThis study aimed to identify...
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Diabetes Therapy Podcast: Real-World Data for Glucose Sensing Technologies in Type 1 Diabetes
For people living with type 1 diabetes (T1D), home glucose monitoring has evolved from occasional qualitative urine tests to frequently sampled...
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Real-world practice patterns of eplerenone use for central serous chorioretinopathy
PurposeTo report eplerenone use by retina specialists worldwide for central serous chorioretinopathy (CSCR).
MethodsA self-reporting questionnaire...
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Clinical outcomes of adjuvant nivolumab in resected stage III melanoma: comparison of CheckMate 238 trial and real-world data
ObjectivesNivolumab is approved as adjuvant therapy for resected stage III/IV melanoma based on the phase 3 CheckMate 238 trial. This analysis...
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Andexanet Alfa: What We Have Learned from Clinical Trials and Real-World Data
Andexanet alfa is a specific reversal agent for factor Xa inhibitors with immediate reversal of their anticoagulant effect. Andexanet alfa is...
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Harnessing the Potential of Real-World Evidence in the Treatment of Colorectal Cancer: Where Do We Stand?
Treatment guidelines for colorectal cancer (CRC) are primarily based on the results of randomized clinical trials (RCTs), the gold standard...
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UroPredict: Machine learning model on real-world data for prediction of kidney cancer recurrence (UroCCR-120)
Renal cell carcinoma (RCC) is most often diagnosed at a localized stage, where surgery is the standard of care. Existing prognostic scores provide...
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Promise of Real-World Evidence for Patient Centricity in Gulf Cooperation Council Countries: Call to Action
Presently, Gulf Cooperation Council countries are lagging in the generation of real-world data and use of real-world evidence for patient-centered...
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Exact-matching algorithms using administrative health claims database equivalence factors for real-world data analysis based on the target trial emulation framework
Real-world data have become increasingly important in medical science and healthcare. A new, effective, and practically feasible statistical design...
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A US real-world study of treatment patterns and outcomes in localized or locally advanced prostate cancer patients
PurposeMen with localized or locally advanced prostate cancer (LPC/LAPC) are at risk of progression after radiotherapy (RT) or radical prostatectomy...
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The impact of menopause on antidepressant response: an explorative analysis from a real-world study
This study endeavors to deepen our understanding of the subject matter by exploring, within a real-world sample, the impact of menopausal status on...
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Real-world effectiveness and satisfaction with intravenous eptinezumab treatment in patients with chronic migraine: REVIEW, an observational, multi-site, US-based study
BackgroundDespite recent advancements in migraine treatment, some patients continue to endure significant disease burden. Due to the controlled...
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Outcomes of Drug Interactions Between Antiretrovirals and Co-Medications, Including Over-the-Counter Drugs: A Real-World Study
IntroductionThe objective was to characterize real-world outcomes of drug–drug interactions (DDIs) between antiretrovirals (ARVs) and other drugs,...
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Real-World Evidence on Levetiracetam-Induced Hypokalemia: An Active Comparator Cohort Study
BackgroundLevetiracetam is an anti-seizure medication (ASM) with an established safety profile. However, a potential safety signal of hypokalemia...
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Real-World Clinical Experience of Oral Semaglutide in a Secondary Diabetes Clinic in the UK: A Retrospective Observational Study
IntroductionOral semaglutide improves cardiovascular risk factors in people with type 2 diabetes (T2D) in clinical trials, though real-world evidence...
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Evaluation of reporting quality of cohort studies using real-world data based on RECORD: systematic review
ObjectiveReal-world data (RWD) and real-world evidence (RWE) have been paid more and more attention in recent years. We aimed to evaluate the...
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Economic Burden of Parkinson’s Disease: A Multinational, Real-World, Cost-of-Illness Study
BackgroundParkinson’s disease is now one of the fastest-growing neurodegenerative disorders in the developed world, with an increasing prevalence and...
