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Risk Minimization of Antibody–Drug Conjugates in Oncology: A Review
Antibody–drug conjugates (ADCs) are new treatment options for certain cancers, especially those in advanced states with limited treatment options....
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Systemic inflammatory changes and their clinical implications following thoracic cancer surgery
Trauma that follows every surgical procedure triggers an inflammatory response, which in the majority of the cases reflects the associated tissue...
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High-intensity Focused Ultrasound-A New Choice to Conduct Pulmonary Artery Denervation
This research aimed to explore whether high-intensity focused ultrasound (HIFU) could conduct pulmonary artery denervation (PADN). HIFU was performed...
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Analysis of donor morbidity in 177 donor hepatectomies for living donor liver transplant: Experience from a high-volume centre in western India
BackgroundLiving donor liver transplant (LDLT) is based on the principle of double equipoise. Organ shortage in Asian countries has led to...
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Cardiac Sympathetic Denervation for the Management of Ventricular Arrhythmias
BackgroundThe autonomic nervous system contributes to the pathogenesis of ventricular arrhythmias (VA). Though anti-arrhythmic drug therapy and...
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Feasibility and efficacy of cryoneurolysis analgesia in robotic-assisted thoracoscopic surgery (CARTS): a pilot study
Opioid therapy has been the mainstay therapy of post-operative pain management in thoracic surgery patients. With the high incidence of chronic pain...
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WNT ligands in non-small cell lung cancer: from pathogenesis to clinical practice
Non-small cell lung cancer (NSCLC) is the malignant tumor with the highest morbidity and leading cause of death worldwide, whereas its pathogenesis...
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The IL-17 family in diseases: from bench to bedside
The interleukin-17 (IL-17) family comprises six members (IL-17A–17F), and recently, all of its related receptors have been discovered. IL-17 was...
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Liver Regeneration is Preserved After At Least Four Repeated Liver Resections for Hepatocellular Carcinoma
IntroductionRepeated resection is known to prolong survival, with an acceptable morbidity rate, in patients with hepatocellular carcinoma. However,...
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Overcoming on-target, off-tumour toxicity of CAR T cell therapy for solid tumours
Therapies with genetically modified T cells that express chimeric antigen receptors (CARs) specific for CD19 or B cell maturation antigen (BCMA) are...
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Efficacy and safety of heparin plus dexamethasone after partial splenic embolization for liver cirrhosis with massive splenomegaly
PurposeThe aim of this study was to investigate the efficacy and safety of the combination of low-molecular-weight heparin + dexamethasone after...
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Therapeutic angiogenesis with exosomal microRNAs: an effectual approach for the treatment of myocardial ischemia
Therapeutic angiogenesis presents a potential approach for treating ischemic heart diseases especially in patients who are not appropriate candidates...
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Low preoperative prealbumin predicts the prevalence of complications following liver transplantation
BackgroundAs a nutritional index, preoperative serum prealbumin highly correlates with surgical complications. However, the correlation between...
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Severe Candida glabrata pancolitis and fatal Aspergillus fumigatus pulmonary infection in the setting of bone marrow aplasia after CD19-directed CAR T-cell therapy – a case report
BackgroundProlonged myelosuppression following CD19-directed CAR T-cell transfusion represents an important, yet underreported, adverse event. The...
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Daily serum phosphate increase as early and reliable indicator of kidney injury in children with leukemia and lymphoma develo** tumor lysis syndrome
BackgroundTumor lysis syndrome (TLS) and its most serious complication, acute kidney injury (AKI) are one of the emergency conditions in...
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Central airway obstruction: is it time to move forward?
IntroductionCentral airway obstruction (CAO) represents a pathological condition that can lead to airflow limitation of the trachea, main stem bronchi ...
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The rex shunt for left portal vein reconstruction during hepatectomy for malignancy using of rex-shunt in adults for oncoliver surgery
BackgroundImmediate portal reperfusion is mandatory following hepatectomy combined with portal vein (PV) resection. This retrospective study analyzes...
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Crosstalk Between the Nervous System and Systemic Organs in Acute Brain Injury
Organ crosstalk is a complex biological communication between distal organs mediated via cellular, soluble, and neurohormonal actions, based on a...
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Effects of intravenous and transdermal photobiomodulation on the postoperative complications of coronary artery bypass grafting surgery: a randomized, controlled clinical trial
Although coronary artery bypass graft (CABG) surgery is one of the most worldwide commonly performed cardiac surgeries to enhance myocardial...
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Stem cell nebulization therapy for COVID-19 infection: radiological and clinical outcomes
BackgroundSARS-CoV-2 is a highly contagious virus that spread worldwide with a rapid increase in the number of deaths. In March 2020, the WHO...
