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Allogeneic Serum Eye Drops: A Randomized Clinical Trial to Evaluate the Clinical Effectiveness of Two Drop Sizes
IntroductionAllogeneic serum from blood donors is starting to be used to treat patients with dry eye disease (DED). However, the optimal dose is not...
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The effect of 8 weeks of endurance and resistance exercises on the serum levels of FGF23 and s-Klotho in type 2 diabetic women
BackgroundIt has been reported that exercise could improve diabetes via the VitD-FGF23-sKlotho axis.
ObjectiveWe evaluated the effects of 8 weeks of...
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Risk factors in patients with acute fatty liver of pregnancy: the role of abortion, total bilirubin and serum creatinine
PurposeAcute fatty liver of pregnancy (AFLP) is a relatively rare obstetric emergency usually accompanied by fatal complications. Numerous studies...
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Impact of BMI on serum 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D with calcifediol supplementation in young adults: a longitudinal study
BackgroundHigh body mass index (BMI) is a risk factor for vitamin D deficiency. The rise in serum 25-hydroxyvitamin D [25(OH)D] concentrations...
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Calcium chloride dihydrate supplementation at ICSI improves fertilization and pregnancy rates in patients with previous low fertilization: a retrospective paired treatment cycle study
PurposeTo determine if 5mM calcium chloride dihydrate supplementation of the Polyvinylpyrrolidone (PVP) media at the time of ICSI (ICSI-Ca) improves...
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Serum MicroRNA profiles in chronic hepatitis C Egyptian patients before and after combined sofosbuvir and daclatasvir treatment
BackgroundMicroRNAs (miR) are small sequence of nucleotides that can affect multiple genes involved in the hepatitis C virus (HCV) life cycle and...
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Effects of Pentoxifylline on Serum Markers of Diabetic Nephropathy in Type 2 Diabetes
ObjectiveTo investigate the effects of pentoxifylline (PTX) in combination with losartan compared to the high dose of losartan alone on serum markers...
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Identification of the Minimum Combination of Serum microRNAs to Predict the Recurrence of Colorectal Cancer Cases
BackgroundSerum microRNAs (miRNAs) have been recognized as potential stable biomarkers for various types of cancer. Considering the clinical...
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Changes in metabolic parameters and serum YKL-40 levels in Chinese rheumatoid arthritis patients during tocilizumab therapy
ObjectiveTo investigate the metabolic changes during therapy of tocilizumab (TCZ) and methotrexate (MTX) in non-diabetic rheumatoid arthritis (RA)...
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IgE anti-BP180 NC16A autoantibody in both serum and blister fluid samples does not correlate with disease activity of bullous pemphigoid
BackgroundThe correlation between IgE anti-BP180 NC16A autoantibody and disease activity of bullous pemphigoid (BP) remains disputable.
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Plasma and serum prorenin concentrations in diabetes, hypertension, and renal disease
Although the renin–angiotensin–aldosterone system plays a crucial role in fluid homeostasis and cardiovascular disease pathophysiology, measurements...
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Differential expression and analysis of extrachromosomal circular DNAs as serum biomarkers in pulmonary arterial hypertension
BackgroundExtrachromosomal circular DNAs (eccDNAs) have been reported to play a key role in the occurrence and development of various diseases....
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FJX1 as a candidate diagnostic and prognostic serum biomarker for colorectal cancer
PurposeColorectal cancer (CRC) is one of the most common cancer worldwide. It is essential to identify non-invasive diagnostic and prognostic...
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Serum levels of galactose-deficient IgA are elevated in patients with IgA nephropathy but do not correlate to disease activity or progression
IntroductionIgA nephropathy (IgAN) is the most common glomerulonephritis globally. Because of the heterogeneity of the disease prognostic biomarkers...
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Longitudinal changes in serum adropin levels and liver fat content during liraglutide treatment in newly diagnosed patients with type 2 diabetes mellitus and metabolic dysfunction-associated fatty liver disease
AimsTo explore the effect of liraglutide treatment on serum adropin and its relationship to the liver fat content in newly diagnosed patients with...
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Serum glucose, a cost-effective alternate of plasma glucose in diagnosing and monitoring diabetes mellitus
BackgroundMeasurement of venous plasma glucose concentration (P-Glucose) requires preanalytical precautions: rapid cooling, rapid centrifugation, and...
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Effect of dapagliflozin on proteomics and metabolomics of serum from patients with type 2 diabetes
BackgroundSodium-glucose co-transporter 2 (SGLT2) inhibitors reduced the risk of cardiovascular and renal outcomes in patients with type 2 diabetes...
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Comparison of olfactory function, cognitive function and serum tumor necrosis factor-α between bipolar and schizophrenic patients in the remission stage
ObjectivesOlfactory function, serum tumor necrosis factor-α (TNF-α) and cognitive function were compared between bipolar disorder (BD) and...
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Effect of pioglitazone on serum FGF23 levels among patients with diabetic kidney disease: a randomized controlled trial
AimElevated fibroblast growth factor-23 (FGF23) is an established marker of cardiovascular disease among patients with type 2 diabetes (T2DM) and...
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Higher serum uric acid is associated with poorer cognitive performance in healthy middle-aged people: a cross-sectional study
Age-related cognitive impairment can occur many years before the onset of the clinical symptoms of dementia. Uric acid (UA), a metabolite of...