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Adherence to antidiabetic drug therapy and reduction of fatal events in elderly frail patients
BackgroundTo evaluate the protective effect of oral antidiabetic drugs in a large cohort of elderly patients with type 2 diabetes differing for age,...
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Capturing the variety of clinical pathways in patients with schizophrenic disorders through state sequences analysis
BackgroundCare pathways are increasingly being used to enhance the quality of care and optimize the use of resources for health care. Nevertheless,...
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Diabetes mellitus duration and mortality in patients hospitalized with acute myocardial infarction
BackgroundDiabetes mellitus (DM) is associated with an increased mortality risk in patients hospitalized with acute myocardial infarction (AMI);...
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Radiotherapy for oligometastatic cancer: a survey among radiation oncologists of Lombardy (AIRO-Lombardy), Italy
AimsTo evaluate the use of radiotherapy (RT) for oligometastatic cancer (OMC) among radiation oncologists in Lombardy, Italy.
Methods and study design ... -
Impact of chronic GLP-1 RA and SGLT-2I therapy on in-hospital outcome of diabetic patients with acute myocardial infarction
BackgroundGlucagon-like peptide-1 receptor agonists (GLP-1 RA) and sodium glucose cotransporter-2 inhibitors (SGLT-2i) demonstrated cardiovascular...
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Factors associated with pharmacological treatment in children with attention-deficit/hyperactivity disorders: a retrospective study of a series of 77 cases in a single third-level reference Centre in Apulia region
BackgroundThe present study analysed data on children and adolescents with a diagnosis of attention-deficit/hyperactivity disorder (ADHD) who were...
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Protective action of natural and induced immunization against the occurrence of delta or alpha variants of SARS-CoV-2 infection: a test-negative case-control study
BackgroundThe evolution of SARS-CoV-2 has led to the emergence of several new variants, and few data are available on the impact of vaccination on...
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Herpes zoster (HZ) vaccine coverage and confidence in Italy: a Nationwide cross-sectional study, the OBVIOUS project
BackgroundHerpes Zoster is an age dependent disease and as such it represents a problem in the Italian social context, where the demographic curve is...
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Effectiveness and safety of GLP-1 receptor agonists versus SGLT-2 inhibitors in type 2 diabetes: an Italian cohort study
BackgroundGLP-1 receptor agonists (GLP-1 RA) and SGLT-2 inhibitors (SGLT-2i) have shown to reduce the risk of major adverse cardiovascular events...
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Psychological distress among Italians during the 2019 coronavirus disease (COVID-19) quarantine
BackgroundQuarantine as a preventive action to reduce people’s exposure to a contagious disease has substantial psychological impact. We aimed to...
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Adherence to Lipid-Lowering Treatment by Single-Pill Combination of Statin and Ezetimibe
IntroductionAlthough several studies have shown that a simplified cardiovascular drug treatment leads to better treatment adherence, limited and...
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Exploring gender differences in medication consumption and mortality in a cohort of hypertensive patients in Northern Italy
BackgroundThis paper aims to assess the presence of gender differences in medication use and mortality in a cohort of patients affected exclusively...
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Patients’ treatment limitations as predictive factor for mortality in COVID-19: results from hospitalized patients of a hotspot region for SARS-CoV-2 infections
BackgroundIn hospitalized patients with SARS-CoV-2 infection, outcomes markedly differ between locations, regions and countries. One possible cause...
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The impact of early therapies for COVID-19 on death, hospitalization and persisting symptoms: a retrospective study
PurposeOral antivirals (nirmatrelvir/ritonavir and molnupiravir), intravenous short treatment of remdesivir and anti-SARS-CoV-2 monoclonal antibodies...
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Advice of General Practitioner, of Surgeon, of Endocrinologist, and Self-determination: the Italian Road to Bariatric Surgery
PurposeBariatric surgery (BS) is considered the most efficient treatment for severe obesity. International guidelines recommend multidisciplinary...
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Do Strategies Favoring Frozen-thawed Embryo Transfer Have an Impact on Differences in IVF Success Rate, Multiple Pregnancy Rate, and Cost per Live Birth Between Fertility Clinics?
The aim of this retrospective cohort study is to establish whether strategies favoring frozen-thawed embryo transfer (FET) have an impact on...
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First imported case of Candida auris infection in Milan, Italy: genomic characterisation
PurposeCandida auris , an emerging multidrug-resistant yeast, has been reported worldwide. In Italy, the first case was reported in 2019. We describe...