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Clinical characteristics and impact of comorbidities on the prognosis of senile epilepsy in Southwest China: a retrospective cohort study
BackgroundSenile epilepsy and its comorbidities pose a tremendous burden on patients and the society. This study was aimed to investigate the...
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Multivariate analysis of seizure outcomes after resective surgery for focal epilepsy: a single-center study on 833 patients
The predictors of seizure outcomes after resective surgery for focal epilepsy, for an update on the features of good and poor outcomes, are...
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Epilepsy surgery in older patients – English Version
Removal of the seizure focus, either by resection or by laser thermal ablation, has a high chance to result in seizure freedom in well-selected...
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Epilepsy Treatment in Patients with Heart Disease
Purpose of reviewThis review highlights issues pertaining to the treatment of seizures in patients with cardiac disease. These fall into two...
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The Current Role of Valproic Acid in the Treatment of Epilepsy: A Glimpse into the Present of an Old Ally
Purpose of the reviewThe primary purpose of this review is to explore the specific clinical scenarios where valproic acid demonstrates superiority...
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The phenotypic spectrum of epilepsy associated with periventricular nodular heterotopia
BackgroundPeriventricular nodular heterotopia (PVNH) is a congenital brain malformation often associated with seizures. We aimed to clarify the...
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Imaging in medically refractory epilepsy at 3 Tesla: a 13-year tertiary adult epilepsy center experience
ObjectivesMRI negative epilepsy has evolved through increased usage of 3 T and insights from surgically correlated studies. The goal of this study is...
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Brain structural changes in preschool children with MRI-negative epilepsy
PurposeTo investigate abnormalities in cortical and subcortical structures of the brain in preschool children with MRI-negative epilepsy.
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Post-traumatic epilepsy in Cameroon: a retrospective study in a referral hospital
BackgroundPost-traumatic epilepsy is defined as the onset of at least one seizure beyond the first week following a traumatic brain injury (TBI)....
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Sub-region analysis of DMD gene in cases with idiopathic generalized epilepsy
Gene sub-region encoded protein domain is the basic unit for protein structure and function. The DMD gene is the largest coding gene in humans, with...
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Long-term effectiveness and safety of lacosamide as adjunctive therapy in children and adolescents with refractory epilepsy: a real-world study
PurposeThe effectiveness and tolerability of lacosamide (LCM) among Chinese children and adolescents with refractory epilepsy has not yet been...
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Determinants of quality of life in adults with epilepsy: a multicenter, cross-sectional study from Germany
BackgroundAssessment of quality of life (QoL) has become an important indicator for chronic neurological diseases. While these conditions often limit...
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Epilepsy and epileptiform activity in late-onset Alzheimer disease: clinical and pathophysiological advances, gaps and conundrums
A growing body of evidence has demonstrated a link between Alzheimer disease (AD) and epilepsy. Late-onset epilepsy and epileptiform activity can...
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Research progress on the electrophysiological indicators to predict the efficacy of vagus nerve stimulation for drug-refractory epilepsy
Vagus nerve stimulation (VNS) is an important treatment option for drug-refractory epilepsy (DRE), with well-established efficacy and safety in...
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Hippocampal sclerosis is associated with celiac disease type immunity in patients with drug-resistant temporal lobe epilepsy
BackgroundA prior small-scale single center study suggested an association between celiac disease (CD)-type immunity and refractory temporal lobe...
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Is there a rationale for treating interictal epileptic discharges in self-limiting epilepsy with centrotemporal spikes (SeLECTS)?
The impact of epilepsy on the quality of life of affected children and their families is dominated by other factors than the seizures. The cognitive...
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Clinical and economic implications of epilepsy management across treatment lines in Spain: a real-life database analysis
BackgroundEpilepsy is a chronic brain disease characterized by recurrent seizures. We investigated real-world management of epilepsy across treatment...
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Brain structural changes and molecular analyses in children with benign epilepsy with centrotemporal spikes
BackgroundBenign epilepsy with centrotemporal spikes (BECTS) is a common childhood epilepsy syndrome, accompanied by behavioral problems and...
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Therapeutic efficacy of voltage-gated sodium channel inhibitors in epilepsy
Epilepsy is a neurological disease characterized by excessive and abnormal hyper-synchrony of electrical discharges of the brain and a predisposition...
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Efficacy and safety of modified medium-chain triglyceride ketogenic diet in patients with drug-resistant epilepsy
BackgroundMedium-chain triglyceride ketogenic diet (MCTKD) is previously less commonly used in China. This study was aimed to assess the efficacy...
