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Changes in concentrations of cervicovaginal immune mediators across the menstrual cycle: a systematic review and meta-analysis of individual patient data
BackgroundHormonal changes during the menstrual cycle play a key role in sha** immunity in the cervicovaginal tract. Cervicovaginal fluid contains...
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Yixin Ningshen Tablet Alleviates Comorbidity of Myocardial Infarction and Depression by Enhancing Myocardial Energy Metabolism and Increasing Availability of Monoamine Neurotransmitter
ObjectiveTo investigate the therapeutic effect of Yixin Ningshen Tablet (YXNS) on comorbidity of myocardial infarction (MI) and depression in rats...
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Short isoform thymic stromal lymphopoietin reduces inflammation and aerobic glycolysis of asthmatic airway epithelium by antagonizing long isoform thymic stromal lymphopoietin
BackgroundUp-regulation of aerobic glycolysis has been reported as a characterization of asthma and facilitates airway inflammation. We has been...
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Chicken cathelicidin-2 promotes NLRP3 inflammasome activation in macrophages
Chicken cathelicidin-2 (CATH-2) as a host defense peptide has been identified to have potent antimicrobial and immunomodulatory activities. Here, we...
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Pyoderma Gangrenosum: An Updated Literature Review on Established and Emerging Pharmacological Treatments
Pyoderma gangrenosum is a rare inflammatory skin disease classified within the group of neutrophilic dermatoses and clinically characterized by...
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Local nebulization of 1α,25(OH)2D3 attenuates LPS-induced acute lung inflammation
BackgroundEvidence supports a critical role of vitamin D status on exacerbation in chronic obstructive pulmonary disease, indicating the need to...
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Hyperferritinemic sepsis, macrophage activation syndrome, and mortality in a pediatric research network: a causal inference analysis
BackgroundOne of five global deaths are attributable to sepsis. Hyperferritinemic sepsis (> 500 ng/mL) is associated with increased mortality in...
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Cationic peptide carriers enable long-term delivery of insulin-like growth factor-1 to suppress osteoarthritis-induced matrix degradation
BackgroundInsulin-like growth factor-1 (IGF-1) has the potential to be used for osteoarthritis (OA) treatment but has not been evaluated in clinics...
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Altered gut microbiota and its association with inflammation in patients with chronic thromboembolic pulmonary hypertension: a single-center observational study in Japan
BackgroundThe pathogenesis of chronic thromboembolic pulmonary hypertension (CTEPH) is considered to be associated with chronic inflammation;...
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JianPiYiShen formula prevents cisplatin-induced acute kidney injury in mice by improving necroptosis through MAPK pathway
BackgroundAcute kidney injury (AKI), characterized by necroptosis and activation of MAPK pathway, causes sudden declines in renal function. To date,...
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Tear fluid cytokine analysis: a non-invasive approach for assessing retinopathy of prematurity severity
PurposeTo determine whether there is a significant association between inflammatory cytokines in the tear fluid and the severity of Retinopathy of...
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The assessment of the concentration of candidate cytokines in response to conjunctival-exposure of atmospheric low-temperature plasma in an animal model
BackgroundAtmospheric Low-Temperature Plasma (ALTP) can be used as an effective tool in conjunctival cyst ablation, but little is known about how...
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Effects of a water-soluble formulation of tylvalosin on disease caused by porcine reproductive and respiratory syndrome virus alone in sows or in combination with Mycoplasma hyopneumoniae in piglets
BackgroundThe effect of a water-soluble formulation of tylvalosin (Aivlosin® 625 mg/g granules) on disease caused by porcine reproductive and...
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Glycyrrhizic Acid Protects Glomerular Podocytes Induced by High Glucose by Modulating SNARK/AMPK Signaling Pathway
ObjectiveDiabetic nephropathy is one of the most important microvascular complications of diabetes, which mainly refers to glomerular capillary...
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Effects of local cryotherapy on systemic endothelial activation, dysfunction, and vascular inflammation in adjuvant-induced arthritis (AIA) rats
AimThis study explored the systemic vascular effects of local cryotherapy with a focus on endothelial changes and arterial inflammation in the model...
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Efficacy of Avène Hydrotherapy on Chronic Pruritus in Patients with Plaque Psoriasis
IntroductionPruritus is a prevalent symptom, described as one of the most bothersome of psoriasis. Specific itch management remains a challenge, for...
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Sex-specific association of visceral and subcutaneous adipose tissue volumes with systemic inflammation and innate immune cells in people living with obesity
Background and aimsObesity predisposes to metabolic and cardiovascular diseases. Adipose tissue inflammation and systemic inflammation contribute to...
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Effects of remote ischemic preconditioning (RIPC) and chronic remote ischemic preconditioning (cRIPC) on levels of plasma cytokines, cell surface characteristics of monocytes and in-vitro angiogenesis: a pilot study
Remote ischemic preconditioning (RIPC) protects the heart against myocardial ischemia/reperfusion (I/R) injury and recent work also suggested chronic...
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Infants with Down syndrome and congenital heart disease have altered peri-operative immune responses
BackgroundInfants with Down syndrome (DS) have an altered immune response. We aimed to characterise the inflammatory response in infants with DS and...
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Chemokine profile in women with moderate to severe anxiety and depression during pregnancy
BackgroundCytokine levels have been extensively described in pregnant subjects under normal and pathological conditions, including mood-related...
