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Clinical outcome, radiological findings, and genetic features of IDH-mutant brainstem glioma in adults
BackgroundWith the recent advent of genetic testing, IDH-mutant glioma has been found among adult brainstem gliomas. However, the clinical outcome...
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C-Fos-activated circRPPH1 contributes to glioma stemness
ObjectiveCancer stem cells or cancer stemness has been confirmed to a major obstacle for glioma progression and it has also been reported that...
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The clinical, radiological, and surgical characteristics of anterior perforated substance glioma: a retrospective study
BackgroundTo explore the clinical, radiological, and surgical characteristics of anterior perforated substance (APS) gliomas.
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Structural connectome combining DTI features predicts postoperative language decline and its recovery in glioma patients
ObjectivesA decline in language function is a common complication after glioma surgery, affecting patients’ quality of life and survival. This study...
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Low-coverage and cost-effective whole-genome sequencing assay for glioma risk stratification
PurposeTo investigate chromosomal instability (CIN) as a biomarker for glioma risk stratifications, with cost-effective, low-coverage whole-genome...
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Fear stress promotes glioma progression through inhibition of ferroptosis by enhancing FSP1 stability
PurposePatients diagnosed with cancer often suffer from emotional stressors, such as anxiety, depression, and fear of death. However, whether fear...
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Distinct immune escape and microenvironment between RG-like and pri-OPC-like glioma revealed by single-cell RNA-seq analysis
The association of neurogenesis and gliogenesis with glioma remains unclear. By conducting single-cell RNA-seq analyses on 26 gliomas, we reported...
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Increase in serum vimentin levels in patients with glioma and its correlation with prognosis of patients with glioblastoma
Early diagnosis of glioma is of great value to improve prognosis. We focused on serum vimentin levels as a useful biomarker for preoperative...
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Glioma immunotherapy enhancement and CD8-specific sialic acid cleavage by isocitrate dehydrogenase (IDH)-1
The promise of adaptive cancer immunotherapy in treating highly malignant tumors such as glioblastoma multiforme (GBM) can only be realized through...
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How modern treatments have modified the role of surgery in pediatric low-grade glioma
Low-grade gliomas are the most common brain tumor of childhood, and complete resection offers a high likelihood of cure. However, in many instances,...
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Tool-tissue interaction force in glioma surgery
ObjectiveAmong neurosurgical patients, using sensorized bipolar forceps, we have previously shown that high force error is often associated with...
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ADAMTS1 as potential prognostic biomarker promotes malignant invasion of glioma
BackgroundGlioma is the most common intracranial malignancy in adults with a high degree of malignancy and poor prognosis, which is largely...
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Using machine learning-based radiomics to differentiate between glioma and solitary brain metastasis from lung cancer and its subtypes
ObjectiveTo establish a machine learning-based radiomics model to differentiate between glioma and solitary brain metastasis from lung cancer and its...
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Artificial intelligence-based MRI radiomics and radiogenomics in glioma
The specific genetic subtypes that gliomas exhibit result in variable clinical courses and the need to involve multidisciplinary teams of...
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Repeat surgery of recurrent glioma for molecularly informed treatment in the age of precision oncology: A risk–benefit analysis
PurposeSurgery for recurrent glioma provides cytoreduction and tissue for molecularly informed treatment. With mostly heavily pretreated patients...
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Overexpression of TPM4 is associated with worse prognosis and immune infiltration in patients with glioma
BackgroundTropomyosin 4 (TPM4), a member of the tropomyosin family, is aberrantly expressed and plays an important role in a variety of cancers....
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Low-grade glioma of the temporal lobe and tumor-related epilepsy in children
PurposeLow-grade glioma is the most common brain tumor among children and adolescents. When these tumors arise in the temporal lobe, patients...
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Clinicohistoradiological and surgical outcome in diffuse midline glioma
PurposeDiffuse Midline Glioma (DMG) with H3K27M mutation is a rare and aggressive midline high grade glioma with a predominant astrocytic...
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MRI comparative study of diffuse midline glioma, H3 K27-altered and glioma in the midline without H3 K27-altered
PurposeThe MRI features of Diffuse midline glioma, H3 K27-altered and glioma in the midline without H3 K27-altered were compared and analyzed, and...
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Multiparametric MRI radiomics for the differentiation of brain glial cell hyperplasia from low-grade glioma
BackgroundDifferentiating between low-grade glioma and brain glial cell hyperplasia is crucial for the customized clinical treatment of patients.
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