Search
Search Results
-
Multi-omic assessment shows dysregulation of pulmonary and systemic immunity to e-cigarette exposure
Electronic cigarette (Ecig) use has become more common, gaining increasing acceptance as a safer alternative to tobacco smoking. However, the 2019...
-
Salvianolic acid a inhibits platelet activation and aggregation in patients with type 2 diabetes mellitus
BackgroundPlatelets in patients with type 2 diabetes mellitus (DM2) are characterized by increased activation and aggregation, which tends to be...
-
Thrombosis in COVID-19 infection: Role of platelet activation-mediated immunity
BackgroundThrombosis plays an important role in the Coronavrus Disease 2019 (COVID-19) infection-related complications such as acute respiratory...
-
Current and future strategies to monitor and manage coagulation in ECMO patients
Extracorporeal membrane oxygenation (ECMO) can provide life-saving support for critically ill patients suffering severe respiratory and/or cardiac...
-
Anticoagulation in ECMO patients: an overview
Extracorporeal membrane oxygenation (ECMO) is a form of cardiorespiratory support, and is being increasingly used to support refractory heart and...
-
The Effect of Extracellular Vesicles on Thrombosis
The risk of cardiovascular events caused by acute thrombosis is high, including acute myocardial infarction, acute stroke, acute pulmonary embolism,...
-
Dermatological Toxicities of Bruton’s Tyrosine Kinase Inhibitors
The development of Bruton’s tyrosine kinase (BTK) inhibitors represents a major breakthrough in the treatment of chronic lymphocytic leukemia and...
-
PI3K inhibitors in thrombosis and cardiovascular disease
Phosphoinositide 3-kinases (PI3Ks) are lipid kinases that regulate important intracellular signalling and vesicle trafficking events via the...
-
The role of extracellular vesicles in rheumatoid arthritis: a systematic review
Rheumatoid arthritis (RA) is a chronic inflammatory disease that carries high social and economic costs and can lead to permanent disability. RA...
-
Differentially expressed proteins in platelets derived from patients with hypertension
Hypertension (HTN) causes end-organ damage and is a major cause of morbidity and mortality globally. Recent studies suggested blood cells participate...
-
BTK Inhibitors in Chronic Lymphocytic Leukemia
Purpose of ReviewThe treatment landscape of chronic lymphocytic leukemia (CLL) has dramatically changed over the last few years with the introduction...
-
Managing Antiphospholipid Syndrome in Children and Adolescents: Current and Future Prospects
Pediatric antiphospholipid syndrome (APS) is a rare acquired multisystem autoimmune thromboinflammatory condition characterized by thrombotic and...
-
Identification BCL6 and miR-30 family associating with Ibrutinib resistance in activated B-cell-like diffuse large B-cell lymphoma
Ibrutinib has clear efficacy for activated B-cell-like diffuse large B cell lymphoma (ABC-DLBCL) in previous clinical researches. However, the...
-
Recent progress in ITP treatment
In this review, the recently approved drugs avatrombopag and fostamatinib, which were not extensively covered within 2019 international...
-
P2Y12 inhibitor monotherapy in patients undergoing percutaneous coronary intervention
For 20 years, dual antiplatelet therapy (DAPT), consisting of the combination of aspirin and a platelet P2Y 12 receptor inhibitor, has been the gold...
-
Platelets: emerging facilitators of cellular crosstalk in rheumatoid arthritis
Rheumatoid arthritis (RA) is an autoimmune disease in which a variety of circulating pro-inflammatory cells and dysregulated molecules are involved...
-
On the dynamics of the human endocrine pancreas and potential consequences for the development of type 1 diabetes
Little is known about the human islet life span, and beta-cell neogenesis is generally considered rare in adults. However, based on available data on...
-
The effects of streptokinase in a Chacma baboon (Papio ursinus) model of acquired thrombotic thrombocytopenic purpura
TTP is a life-threatening disorder with limited pharmaceutical treatment options. Recently, the potential of streptokinase in the treatment of...
-
Increased soluble GPVI levels in cirrhosis: evidence for early in vivo platelet activation
Cirrhosis is a consequence of prolonged liver injury and is characterised by extensive tissue fibrosis: the deposition of collagen-rich extracellular...
