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Control of Murine Primordial Follicle Growth Activation by IκB/NFκB Signaling
The transcription factor NFκB has been associated with the timing of menopause in a large human genome-wide association study. Furthermore,...
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Live birth rates in in vitro fertilization cycles with five or fewer follicles
PurposeTo evaluate live birth rates (LBRs) for in vitro fertilization (IVF) cycles with ≤5 follicles at trigger, with the goal of hel** patients...
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Effect of intra-ovarian injection of platelet-rich plasma on the patients with a poor ovarian response (POR) or premature ovarian insufficiency (POI): a systematic review and meta-analysis
BackgroundPOR or POI poses a significant challenge to fertility treatment with different ovarian stimulation strategies. Intra-ovarian injection of...
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Association between oocyte retrieval technique and number of oocytes retrieved
PurposeTo assess if there is an optimal oocyte retrieval (OR) technique to retrieve a maximum number of oocytes and mature oocytes (MII).
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Can a radiofrequency device reduce the pore size?
A facial pore is an empty funnel-shaped structure filled with cornified cylindrical plugs that can be cosmetically bothersome to some patients. In...
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Differential diagnosis of precocious puberty in girls during the COVID-19 pandemic: a pilot study
BackgroundTo investigate the differential diagnosis of girls aged 6 to 8 years with idiopathic premature thelarche (IPT) and central precocious...
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Sal**ectomy may decrease antral follicle count but not live birth rate for IVF-ET patients aged 35–39 years: a retrospective study
PurposeProblems with fallopian tubes are one of the main reasons for women to undergo in vitro fertilization-embryo transfer (IVF-ET). A large...
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FOXO3 and PTEN expression in the ovary of girls with extra-gonadal cancer with or without chemotherapy treatment prior to cryopreservation
BackgroundFOXO3/pFOXO3 and PTEN expression is known to regulate the dormancy/activation of ovarian primordial follicles. How chemotherapy could...
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The stromal microenvironment and ovarian aging: mechanisms and therapeutic opportunities
For decades, most studies of ovarian aging have focused on its functional units, known as follicles, which include oocytes and granulosa cells....
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Effects of Butylparaben Supplementation on In Vitro Development of Mouse Preantral Follicle
We investigated whether butylparaben supplementation to the culture media negatively effects on in vitro development of mouse preantral follicle. The...
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In vitro growth (IVG) of human ovarian follicles in frozen thawed ovarian cortex tissue culture supplemented with follicular fluid under hypoxic conditions
BackgroundDespite its clinical success rates, transplantation after ovarian tissue cryopreservation (OTC) remains a matter of concern. Certain cancer...
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Ovarian cortical follicle density in infertile women with low anti-Müllerian hormone
PurposeTo evaluate the association between anti-Müllerian hormone (AMH) and follicle density in infertile women with diminished ovarian reserve (DOR)...
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Folliculogenesis and steroidogenesis alterations after chronic exposure to a human-relevant mixture of environmental toxicants spare the ovarian reserve in the rabbit model
BackgroundIndustrial progress has led to the omnipresence of chemicals in the environment of the general population, including reproductive-aged and...
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Amniotic fluid-derived exosomes attenuated fibrotic changes in POI rats through modulation of the TGF-β/Smads signaling pathway
In the current study, we investigated the regenerative effects of amniotic fluid exosomes (AF-Exos) in a rat model for premature ovarian...
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Ligands, Receptors, and Transcription Factors that Mediate Inter-Cellular and Intra-Cellular Communication during Ovarian Follicle Development
Reliably producing a competent oocyte entails a deeper comprehension of ovarian follicle maturation, a very complex process that includes meiotic...
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Age-related decline in the expression of GDF9 and BMP15 genes in follicle fluid and granulosa cells derived from poor ovarian responders
BackgroundGrowth differentiation factor 9 ( GDF9 ) and bone morphogenetic protein 15 ( BMP15 ) genes play important roles in folliculogenesis. Altered...
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The typical polypoid adenomyoma is a special form of endometrial polyp: a case-controlled study with a large sample size
PurposeTo investigate clinicopathological differences between typical endometrial polypoid adenomyomas (TPAs) and endometrial polyps (EPs) and to...
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Novel biallelic loss-of-function variants in ZP1 identified in an infertile female with empty follicle syndrome
PurposeEmpty follicle syndrome (EFS) refers to the inability to obtain mature oocytes after appropriate ovarian stimulation during the process of in...