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Solitary rectal ulcer transformation to cap polyposis in a 15-year-old child
BackgroundCap polyposis (CP) is a benign, non-malignant inflammatory disease that affects the rectum. It usually occurs during the 5th decade of...
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Different phenotypes of gastric fundic gland polyposis and cancer in patients with familial adenomatous polyposis depending on Helicobacter pylori infection
A 37-year-old male with tarry stool presented to our hospital. Esophagogastroduodenoscopy revealed advanced gastric cancer, fundic gland polyposis...
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Favorable clinical efficacy of cytotoxic chemotherapy in patients with progressive desmoid tumors: a retrospective real-world study
BackgroundThe real-world evidence about the efficacy of cytotoxic chemotherapy in desmoid tumors is still limited. We investigated the efficacy of...
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Robotic-assisted colectomy in children: a comparative study with laparoscopic surgery
The aim of this study was to compare outcomes of laparoscopic and robotic-assisted colectomy in children. All children who underwent a colectomy with...
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The anatomy and physiology of the ileal pouch and its relevance to pouch dysfunction
For the last 40 years, the ileal pouch-anal anastomosis has been used in patients with ulcerative colitis, familial adenomatous polyposis, and...
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Clinical issues facing pouch patients: an introduction to a special issue on the ileal pouch
For over 40 years, restorative proctocolectomy has been used in patients with ulcerative colitis or familial adenomatous polyposis undergoing...
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Spectrum of mutations in genes associated with familial colorectal cancer syndrome (MLH1, MSH2, PMS2, MSH6, and APC): A not so common hereditary cancer syndrome in Indian population
Incidence of colorectal cancer (CRC) is lower in India than in other parts of the world. Approximately 5% to 10% of CRC is inherited. Hereditary...
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Filling in the “GAPPS”: an unusual presentation of a child with gastric adenocarcinoma and proximal polyposis of the stomach
Gastric Adenocarcinoma and Proximal Polyposis of the Stomach (GAPPS) is a very rare gastric polyposis syndrome characterized by numerous polyps of...
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Altered microbiota caused by disordered gut motility leads to an overactivation of intestinal immune system in APC1638T mice
Adenomatous polyposis coli ( APC ) is recognized as an antioncogene related to familial adenomatous polyposis and colorectal cancers. However, APC is a...
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Gracilis muscle interposition for pouch-vaginal fistulas: a single-centre cohort study and literature review
BackgroundFirst described by Parks and Nicholls in 1978, the ileal pouch-anal anastomosis (IPAA) has revolutionized the treatment of mucosal...
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Robotic-assisted reoperative ileal pouch–anal anastomosis: robotic pouch excision and pouch revision
BackgroundUp to 20% of patients with ileal pouch will develop pouch failure, ultimately requiring surgical reintervention. As a result of the...
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Detection of novel mitochondrial mutations in cytochrome C oxidase subunit 1 (COX1) in patients with familial adenomatous polyposis (FAP)
BackgroundFamilial adenomatous polyposis (FAP) is an Autosomal dominant inherited disorder and a rare form of colorectal cancer (CRC) that is...
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Cribriform morular thyroid carcinoma: a case report with pathological, immunohistochemical, and molecular findings suggesting an origin from follicular cells (or their endodermal precursors)
Cribriform morular thyroid carcinoma (CMTC) is a rare malignant thyroid tumor with a peculiar growth pattern secondary to permanent activation of the...
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Role of robotic approach in ileal pouch–anal anastomosis (IPAA): A systematic review of the literature
Restorative proctocolectomy with ileal pouch–anal anastomosis (IPAA) has become standard surgical treatment of choice in patients with ulcerative...
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Serrated Polyposis Syndrome: an Update and Review of the Literature
Purpose of reviewWe present an overview on enhancing the identification of patients with serrated polyps (SPs) and serrated polyposis syndrome (SPS),...
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Biological behavior of familial papillary thyroid microcarcinoma: Spanish multicenter study
PurposeFamilial papillary thyroid microcarcinoma (FPTMC) can present a more aggressive behavior than the sporadic microcarcinoma. However, few...
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Prophylaktische Chirurgie bei hereditären gastrointestinalen Dispositionssyndromen
Hereditary gastrointestinal tumor predisposition syndromes can carry a high risk of cancer and pose a major challenge for patients and treating...
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Adenomatous neoplasia in the papilla of Vater endoscopic and/or surgical resection?
BackgroundAdenomatous neoplasia in the papilla of Vater needs to be resected in order not to progress. It can be challenging to distinguish between...
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Colorectal carcinoma occurring via the adenoma–carcinoma pathway in patients with serrated polyposis syndrome
BackgroundAlthough serrated polyposis syndrome (SPS) is associated with an increased colorectal cancer (CRC) risk, the carcinogenic mechanisms remain...
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MRI of the ileal pouch
Ileal pouch surgery is the surgical gold standard treatment for patients with ulcerative colitis (UC) and familial adenomatous polyposis (FAP)....