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Methylation of promoter region of BRCA1 gene versus pathogenic variants of gene: risk factor or clinical marker of breast cancer
BackgroundIn this study, we compared the contribution of pathogenic variants of the BRCA1/2 genes (5382insC, 185delAG, 6174delT, 4153delA, T300G)...
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SCGN deficiency is a risk factor for autism spectrum disorder
Autism spectrum disorder (ASD) affects 1–2% of all children and poses a great social and economic challenge for the globe. As a highly heterogeneous...
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Alcohol consumption may be a risk factor for cerebrovascular stenosis in acute ischemic stroke and transient ischemic attack
BackgroundAtherosclerosis are well established risk factors for ischemic stroke, however the association between alcohol consumption and...
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Risk-Factor Based Lead Screening and Correlation with Blood Lead Levels in Pregnancy
ObjectivesLead exposure has devastating neurologic consequences for children and may begin in utero. The American College of Obstetricians and...
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Psychological trauma as a transdiagnostic risk factor for mental disorder: an umbrella meta-analysis
This umbrella review is the first to systematically examine psychological trauma as a transdiagnostic risk factor across psychiatric conditions. We...
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The effect of environmental factors on precocious puberty in children: a case–control study
BackgroundRecently the prevalence of precocious puberty development is increasing among Chinese children. Proper understanding of the risk factors...
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Porphyromonas gulae infection in canines, pet owners and veterinarians in China: an epidemiological study and risk factor analysis
Porphyromonas gulae is a clinically prevalent, anaerobic, oral bacteria in canines, that may be a causative agent of canine periodontal disease, and...
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Mother’s knowledge for environmental risks and self-awareness for the presence of pollutants in her living area in West and Central Anatolia: a cross-sectional survey
BackgroundEnvironmental risk awareness is a key concept to raise awareness and plan future programs for environmental protection. A cross-sectional...
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Environmental health and clinicians: time to promote more action
Climate change and ambient air pollution are threats to human health, with dramatic short- and long-term effects on mortality and morbidity....
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The proximity between styloid process and internal carotid artery as a possible risk factor for dissection: a case–control study
PurposeThe anatomical proximity of the styloid process (SP) to the ipsilateral internal carotid artery (ICA) has been recently recognized as a...
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The orphan receptor GPR88 controls impulsivity and is a risk factor for Attention-Deficit/Hyperactivity Disorder
The neural orphan G protein coupled receptor GPR88 is predominant in the striatum and cortex of both rodents and humans, and considered a potential...
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Genetic architecture of mammographic density as a risk factor for breast cancer: a systematic review
BackgroundMammography Density (MD) is a potential risk marker that is influenced by genetic polymorphisms and can subsequently modulate the risk of...
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The environmental risk factors prior to conception associated with placental abruption: an umbrella review
BackgroundThe present umbrella review evaluated risk factors prior to conception associated with placental abruption based on meta-analyses and...
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Levels and correlates of risk factor control in diabetes mellitus –ELSA-Brasil
BackgroundControl of glucose, blood pressure, cholesterol, and smoking improves the prognosis of individuals with diabetes mellitus. Our objective...
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Prognostic nutritional index (PNI) is an independent risk factor for the postoperative mortality in geriatric patients undergoing hip arthroplasty for femoral neck fracture? A prospective controlled study
IntroductionHip fracture is very common in advanced ages, and it is very likely that this condition is accompanied by nutritional deficiencies. The...
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Alcohol is a risk factor for helmet non-use and fatalities in off-road vehicle and motorcycle crashes
ObjectivesOff-road vehicle (ORV) and motorcycle use is common in Canada; however, risk of serious injury is heightened when these vehicles are...
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Multiple sclerosis epidemiological trends in Italy highlight the environmental risk factors
Italy is definitely a high-risk country for multiple sclerosis (MS). Over the last 50 years, several epidemiological studies, including longitudinal...
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Body mass index as a dominant risk factor for metabolic syndrome among indonesian adults: a 6-year prospective cohort study of non-communicable diseases
BackgroundNon-communicable diseases (NCDs), notably cardiovascular disease and type 2 diabetes mellitus, are largely driven by metabolic syndrome...
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Is sibship composition a risk factor for childhood asthma? Systematic review and meta-analysis
BackgroundFollowing the “hygiene hypothesis”, the role of sibship composition in asthma and wheezing has been extensively studied, but the findings...
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Nasopharyngeal angiotensin converting enzyme 2 (ACE2) expression as a risk-factor for SARS-CoV-2 transmission in concurrent hospital associated outbreaks
BackgroundWidespread human-to-human transmission of the severe acute respiratory syndrome coronavirus two (SARS-CoV-2) stems from a strong affinity...
