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Predicting Risk Stratification in Early-Stage Endometrial Carcinoma: Significance of Multiparametric MRI Radiomics Model
Endometrial carcinoma (EC) risk stratification prior to surgery is crucial for clinical treatment. In this study, we intend to evaluate the...
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Secretomes from Conventional Insemination and Intra-Cytoplasmic Sperm Injection Derived Embryos Differentially Modulate Endometrial Cells In Vitro
Conventional Insemination (CI) and Intra-Cytoplasmic Sperm Injection (ICSI) are routinely used insemination methods in clinical Assisted Reproductive...
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Proton beam therapy for the isolated recurrence of endometrial cancer in para-aortic lymph nodes: a case report
BackgroundProton beam therapy penetrates tumor tissues with a highly concentrated dose. It is useful when normal structures are too proximate to the...
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Metformin and progestins in women with atypical hyperplasia or endometrial cancer: systematic review and meta-analysis
PurposeTo assess metformin's effectiveness in adding it to progestin-based hormone therapy for treating atypical endometrial hyperplasia (AEH) and...
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Suspected myometrial invasion on MRI is correlated with worse outcomes of fertility-preserving treatment in young women with endometrial cancer
PurposeMyometrial invasion of endometrial cancer (EC) impairs the effectiveness of progestin-based treatment and results in high risks of disease...
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MELTF Might Regulate Ferroptosis, Pyroptosis, and Autophagy in Platelet-Rich Plasma-Mediated Endometrial Epithelium Regeneration
The endometrial basal layer is essential for endometrial regeneration, whose disruption leads to thin endometrium or intrauterine adhesion (IUA) with...
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Risk-stratification machine learning model using demographic factors, gynaecological symptoms and β-catenin for endometrial hyperplasia and carcinoma: a cross-sectional study
BackgroundDemographic features, suggestive gynaecological symptoms, and immunohistochemical expression of endometrial β-catenin have a prognostic...
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A pathological complete response after immunotherapy with pembrolizumab for distal duodenal adenocarcinoma caused by Lynch syndrome: a case report
Primary adenocarcinoma of the duodenum is a rare neoplasm that is often microsatellite instability-high (MSI-H). Pembrolizumab, a monoclonal...
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Comparison of sentinel lymph node distribution and lymphatic drainage pathway between high- and low-risk endometrial cancers
PurposeThis study aimed to compare the distribution and drainage pathway of sentinel lymph nodes between high- and low-risk endometrial cancers.
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Re-stratification of patients with copy-number low endometrial cancer by clinicopathological characteristics
ObjectiveTo stratify patients with copy-number low (CNL) endometrial cancer (EC) by clinicopathological characteristics.
MethodsEC patients who...
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Changes in physical function in older women with endometrial cancer with or without adjuvant therapy
ObjectiveTo evaluate changes in physical function (PF) for older women with endometrial cancer (EC) + / − adjuvant therapy in the Women’s Health...
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Characteristics of systematic lymph node dissection and influencing factors of sentinel lymph node biopsy using carbon nanoparticles in endometrial carcinoma: a single-center study
BackgroundCarbon nanoparticles (CNPs) are a new tracer for lymph node map**, which can quickly reach and develop lymph nodes through a lymphatic...
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Incorporating Molecular Diagnostics into Treatment Paradigms for Endometrial Cancer
The treatment of endometrial cancer has recently undergone a paradigm shift from using traditional clinical-pathologic factors to molecular...
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Obesity alters the mouse endometrial transcriptome in a cell context-dependent manner
Obesity impacts fertility and is positively correlated with endometrial hyperplasia and endometrial cancer occurrence. Endometrial epithelia often...
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A comparative analysis of MRI findings in endometrial cancer: differentiation between endometrioid adenocarcinoma, serous carcinoma, and clear cell carcinoma
ObjectiveTo assess the magnetic resonance imaging (MRI) findings of endometrial cancers and to reveal the differences between endometrioid carcinoma...
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STAT3 inhibitor BBI608 reduces patient-specific primary cell viability of cervical and endometrial cancer at a clinical-relevant concentration
PurposeAberrant activation of STAT3 signal pathway promotes tumor progression in many solid tumor types, including cervical cancer and endometrial...
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Idiopathic retroperitoneal fibrosis with endometrial cancer: a case report and literature review
BackgroundRetroperitoneal fibrosis is a rare disease characterized by chronic nonspecific inflammation, which leads to clinical compression...
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Impact of surgical approach on progress of disease by type of histology in stage IA endometrial cancer: a matched-pair analysis
BackgroundTo compare the impact of surgical approach on progression free survival (PFS) stratified by histologic type in women diagnosed with stage...
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Pten and Dicer1 loss in the mouse uterus causes poorly differentiated endometrial adenocarcinoma
Endometrial cancer remains the most common gynecological malignancy in the United States. While the loss of the tumor suppressor, PTEN (phosphatase...
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mTOR signaling and endometrial receptivity in infertile women with intramural uterine leiomyomas
BackgroundReceptive endometrium is a restraining factor in the establishment of pregnancy in several estrogen-dependent gynecological disorders...
