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Neuron-specific biomarkers predict hypo- and hyperalgesia in individuals with diabetic peripheral neuropathy
Aims/hypothesisThe individual risk of progression of diabetic peripheral neuropathy is difficult to predict for each individual. Mutations in...
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MRI-based Neuropathy Score Reporting And Data System (NS-RADS): multi-institutional wider-experience usability study of peripheral neuropathy conditions among 32 radiology readers
ObjectiveTo determine the inter-reader reliability and diagnostic performance of classification and severity scales of Neuropathy Score Reporting And...
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Beneficial effects of ferulic acid in streptozotocin-induced diabetic neuropathy in male Wistar rats
ObjectivesThe available medications for diabetes mellitus (DM) are not sufficient to reverse the pathophysiological abnormalities and complications...
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Monotherapy Versus Combination Therapy in the Treatment of Painful Diabetic Neuropathy: A Systematic Review and Meta-analysis
Background and ObjectivePainful peripheral neuropathy is a common and challenging complication of diabetes mellitus. Combination therapy is used...
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Mosaic vs. Single Image Analysis with Confocal Microscopy of the Corneal Nerve Plexus for Diagnosis of Early Diabetic Peripheral Neuropathy
IntroductionThe assessment of the corneal nerve fibre plexus with corneal confocal microscopy (CCM) is an upcoming but still experimental method in...
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High-normal serum carcinoembryonic antigen levels and increased risk of diabetic peripheral neuropathy in type 2 diabetes
BackgroundIncreased serum carcinoembryonic antigen (CEA) levels are reported to be associated with various metabolic and inflammatory diseases. This...
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Diagnostic value of shear wave ultrasound elastography of tibial nerve in patients with diabetic peripheral neuropathy
BackgroundDiabetic peripheral neuropathy (DPN) is a major complication of Diabetes mellitus. So this study aimed at investigation of the value of...
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Impact of vitamin D level in diabetic people with peripheral neuropathy
BackgroundDiabetes mellitus (DM) is a metabolic disease which is complicated by occurrence of diabetic peripheral neuropathy (DPN). Vitamin D...
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Genetic variants of ALR (-106C → T /-12C → G) and serum PKC-δ are associated with peripheral neuropathy in Egyptian diabetic patients with impaired handwriting
PurposeDiabetic peripheral neuropathy can injure the hand median nerve and cause extensive nerve damage. PKC and ALR are associated with progression...
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Evaluation of the clinical value of shear wave elastography for early detection and diagnosis of diabetic peripheral neuropathy: a controlled preliminary prospective clinical study
PurposeThis study aims to analyze the clinical application value of shear wave elastography (SWE) technique for early diagnosis of diabetic...
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A comparative study of Botulinum toxin type A versus conventional oral therapy as a second-line treatment of diabetic neuropathy
BackgroundDiabetes mellitus is commonly complicated by diabetic peripheral neuropathy. Poor adherence to medication is common in diabetic peripheral...
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Association between P300 parameters and cognitive function in people with diabetic neuropathy
PurposeThe purpose of this study was to investigate the association between event-related potential (ERP) P300 with cognitive function in people with...
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Effect of an Exercise Program on the Balance, Gait, Vibration Sense, and Cardiometabolic Parameters Among Patients with Diabetic Peripheral Neuropathy: a Randomized Controlled Trial
This study was conducted to assess the effect of an exercise program on balance measurements, vibration sense, and walking speed as well as...
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Characterising vincristine-induced peripheral neuropathy in adults: symptom development and long-term persistent outcomes
BackgroundDecades following the introduction of vincristine as treatment for haematological malignancies, vincristine-induced peripheral neuropathy...
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Effect of static magnetic field therapy on diabetic neuropathy and quality of life: a double-blind, randomized trial
BackgroundDiabetic peripheral neuropathy (DPN) is a common complication of diabetes mellitus (DM) that can cause annoying symptoms. To address this...
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Association Between HbA1c Levels and Diabetic Peripheral Neuropathy: A Case–Control Study of Patients with Type 2 Diabetes Using Claims Data
BackgroundEvidence on the efficacy of glycemic control for diabetic peripheral neuropathy (DPN) is limited in patients with type 2 diabetes mellitus....
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Early detection and treatment device for diabetic foot neuropathy
BackgroundDiabetic foot neuropathy is one of the complications of diabetes that affects around 50% of diabetic people. Because peripheral neuropathy...
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Sphaeranthus indicus Linn ameliorates streptozotocin-induced experimental diabetic neuropathy by targeting oxidative stress-mediated alterations
BackgroundDiabetes-induced neuropathic pain is manifested as a lowering of nerve transmission rate, increased discomfort, sensual loss, and axonal...
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A Brief Review on the Novel Therapies for Painful Diabetic Neuropathy
Purpose of ReviewAlmost half of people diagnosed with diabetes mellitus will develop painful diabetic neuropathy (PDN), a condition greatly impacting...
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Effect of novel Matrix Rhythm Therapy (MaRhyThe®) on neuropathic pain and maximum plantar pressure distribution among type 2 diabetes mellitus patients with peripheral neuropathy
BackgroundThere is a need for a non-pharmacological approach to reduce pain and plantar pressure in diabetic peripheral neuropathy (DPN). Matrix...
