Search
Search Results
-
Nivolumab-related myasthenia gravis with myositis requiring prolonged mechanical ventilation: a case report
BackgroundNivolumab is an immune checkpoint inhibitor that blocks inhibitors of T-cell activation and blunts antitumor immunity and is used in the...
-
New insights into the immune functions of podocytes: the role of complement
Podocytes are differentiated epithelial cells which play an essential role to ensure a normal function of the glomerular filtration barrier (GFB). In...
-
Adenovirus Infection in Patients Undergoing Hematopoietic Stem Cell Transplantation
Purpose of ReviewAdenovirus (AdV) is a relatively common cause of viral infection in the general population, especially in childhood. In patients...
-
-
Renal Disease in Primary Sjögren’s Syndrome
Primary Sjögren’s syndrome (pSS) is a chronic autoimmune disorder characterised by lymphocytic infiltration of the exocrine glands, predominantly the...
-
Genetics of SLE: mechanistic insights from monogenic disease and disease-associated variants
The past few years have provided important insights into the genetic architecture of systemic autoimmunity through aggregation of findings from...
-
Type I interferon pathway in pediatric systemic lupus erythematosus
BackgroundThe role of type I interferon (IFN-I) signaling in systemic lupus erythematosus (SLE) has been well established. However, unanswered...
-
Cyclophosphamide for salvage therapy of chronic graft-versus-host disease: a retrospective analysis
We retrospectively analyzed the safety and efficacy of cyclophosphamide (cyclo) for salvage treatment of chronic graft-versus-host disease (cGvHD)...
-
Hyporeninemic hypoaldosteronism in RMND1-related mitochondrial disease
BackgroundRMND1 is a nuclear gene needed for proper function of mitochondria. A pathogenic gene will cause multiple oxidative phosphorylation...
-
A case of rapidly progressive glomerulonephritis with double-positive anti-GBM antibody and MPO-ANCA after SARS-CoV-2 vaccination and relapse during 1 year follow-up
Although mRNA vaccines for COVID-19 are highly beneficial and are recommended for patients with kidney disease, adverse reactions in some patients...
-
Histological diagnosis of immune checkpoint inhibitor induced acute renal injury in patients with metastatic melanoma: a retrospective case series report
BackgroundImmune checkpoint inhibitors (ICI) have become the standard of care in many oncological conditions but are associated with a spectrum of...
-
A child with crescentic glomerulonephritis following SARS-CoV-2 mRNA (Pfizer-BioNTech) vaccination
BackgroundThere are few reports on kidney complications after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) messenger RNA (mRNA)...
-
Sirtuins in kidney health and disease
Sirtuins (SIRTs) are putative regulators of lifespan in model organisms. Since the initial discovery that SIRTs could promote longevity in nematodes...
-
New-onset acute psychosis as a manifestation of lupus cerebritis following concomitant COVID-19 infection and vaccination: a rare case report
BackgroundRare cases of COVID-19 infection- and vaccine-triggered autoimmune diseases have been separately reported in the literature. In this paper,...
-
A case of novel NFKB2 variant with hypertensive emergency and nephrotic syndrome leading to CKD 5D
AbstractNuclear factor kappa B (NF-κB) family plays a central role in the human immune system. Heterozygous variants in NFKB2 typically cause...
-
Automated electrochemiluminescence immunoassay for serum PlGF levels in women with singleton pregnancy at 9–13 weeks of gestation predicts preterm preeclampsia: a retrospective cohort study
Our aims were to obtain the gestational-age-specific median of common logarithmic placental growth factor (PlGF) values in the first trimester in...
-
Epidemiology of hyperkalemia in CKD patients under nephrological care: a longitudinal study
Hyperkalemia is a potential life-threatening condition among chronic kidney disease (CKD) patients. Available estimates of the burden of this...