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Exploring the Efficacy of Biologics in Knee Osteoarthritis: Ultrasound Evaluation of Cartilage Regeneration Effects
IntroductionBiologics like growth factors, stem cells, and platelet-rich plasma show potential in stimulating cartilage regrowth and reducing...
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Fat-suppressed T2 map** of human knee femoral articular cartilage: comparison with conventional T2 map**
BackgroundThere is paucity of studies applying fat suppressed (FS) technique to T2 map** to overcome chemical shift artifacts. The purpose of the...
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Demonstrating the effectiveness of intra-articular prolotherapy combined with peri-articular perineural injection in knee osteoarthritis: a randomized controlled trial
BackgroundThis study aimed to compare the efficacy of intra-articular prolotherapy (IG) combined with peri-articular perineural injection (PG) in the...
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The Rosenberg view and coronal stress radiographs give similar measurements of articular cartilage height in knees with osteoarthritis
PurposeChoosing the optimal radiographic methods to diagnose the cartilage height and degree of knee osteoarthritis is crucial to determine...
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Improvement of clinical and radiological outcomes of root repair patients with advanced articular cartilage degeneration and osteoarthritis
PurposeThe main purpose of this study was to investigate clinical and radiological outcomes of medial meniscus posterior root tear (MMPRT) repair in...
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High tibial osteotomy to neutral alignment improves medial knee articular cartilage composition
PurposeThe purpose of this study was to: (1) test the hypothesis that HTO improves articular cartilage composition in the medial compartment without...
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Comparison of 3T MR arthrography and 3T MRI in intra-articular hip pathology: a cost-analysis
BackgroundMR arthrography (MRA) has previously been the radiological gold standard for investigating labral and chondral lesions of the hip joint. In...
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Long term outcome of surgical treatment of chondroblastoma: analysis of local control and growth plate/articular cartilage related complications
BackgroundChondroblastoma (CBL) is a rare benign chondroid producing bone tumor that typically occurs in epiphysis or apophysis of growing children...
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Biological intra-articular augmentation for osteotomy in knee osteoarthritis: strategies and results
PurposeTo assess whether there is evidence supporting the use of augmentation strategies, either cartilage surgical procedures or injective...
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Repeated intra-articular injections of umbilical cord-derived mesenchymal stem cells for knee osteoarthritis: a phase I, single-arm study
IntroductionStem cell therapy has emerged as an effective treatment for multiple diseases, and some studies also demonstrate that it may be a...
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Interactions of cumulative load with biomarkers of cartilage turnover predict knee cartilage change over 2 years: data from the osteoarthritis initiative
The purpose was to investigate relationships of cumulative load and cartilage turnover biomarkers with 2-year changes in cartilage in knee...
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Immunity-and-matrix-regulatory cells enhance cartilage regeneration for meniscus injuries: a phase I dose-escalation trial
Immunity-and-matrix-regulatory cells (IMRCs) derived from human embryonic stem cells have unique abilities in modulating immunity and regulating the...
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MiR-760 targets HBEGF to control cartilage extracellular matrix degradation in osteoarthritis
The present study was developed to explore whether microRNA (miR)-760 targets heparin-binding EGF-like growth factor (HBEGF) to control cartilage...
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Gaining Insight into Updated MR Imaging for Quantitative Assessment of Cartilage Injury in Knee Osteoarthritis
Purpose of the ReviewKnee Osteoarthritis (KOA) entails progressive cartilage degradation, reviewed via MRI for morphology, biochemical composition,...
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Tongbi Huoluo Decoction alleviates cartilage degeneration in knee osteoarthritis by inhibiting degradation of extracellular matrix
BackgroundKnee osteoarthritis (KOA) is an age-related degenerative disease characterized by abrasion of articular cartilage. Tongbi Huoluo Decoction...
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Intra-articular administration of extra-virgin olive oil in degenerative osteoarthritis
BackgroundWe aimed to analyze the outcomes of intraarticular extra virgin olive oil (EVOO) injection on mechanically induced rabbit knee...
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Particulate cartilage and platelet-rich plasma treatment for knee chondral defects in sheep
PurposeArticular cartilage is vulnerable to multiple types of damage and it has limited reparative and regenerative capacities due to its absence of...
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Quantitative evaluation of very early cartilage damage in experimental osteoarthritis using scanning electron microscopy
ObjectiveTo describe parametric changes observed using scanning electron microscopy (SEM) in very early stages in posttraumatic osteoarthritis (OA)...
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T2-map** MRI evaluation of patellofemoral cartilage in patients submitted to intra-articular platelet-rich plasma (PRP) injections
This study evaluated the ability of T2 map** magnetic resonance imaging at 3 T, in addition to morphological sequences, to assess efficacy of...
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Quantitative T2 map** monitoring the maturation of engineered elastic cartilage in a rabbit model
BackgroundCartilage tissue engineering provides a promising approach to reconstruct craniofacial defects, and a noninvasive method is needed to...
