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Inequalities in colorectal cancer screening uptake in Wales: an examination of the impact of the temporary suspension of the screening programme during the COVID-19 pandemic
BackgroundResponse to the early stages of the COVID-19 pandemic resulted in the temporary disruption of cancer screening in the UK, and strong public...
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Comparison of preoperative NT-proBNP and simple cardiac risk scores for predicting postoperative morbidity after non-cardiac surgery with intermediate or high surgical risk
BackgroundChronic heart failure (HF) is frequent in elderly patients undergoing non-cardiac surgery. Preoperative risk stratification is vital and...
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Contextualizing remote fall risk: Video data capture and implementing ethical AI
Wearable inertial measurement units (IMUs) are being used to quantify gait characteristics that are associated with increased fall risk, but the...
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Clinical service delivery implications of the COVID-19 pandemic on people with Inflammatory bowel disease: a qualitative study
BackgroundDuring the COVID-19 pandemic, clinical services were severely disrupted, restricted, or withdrawn across the country. People living with...
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Evaluating the effect of a behavioural intervention bundle on antibiotic use, quality of care, and household transmission of resistant Enterobacteriaceae in intervention versus control clusters in rural Burkina Faso and DR Congo (CABU-EICO)
BackgroundAntimicrobial resistance (AMR) is a rising threat in low-resource settings, largely driven by transmission in the community, outside health...
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Using pre-fracture mobility to augment prediction of post-operative outcomes in hip fracture
PurposePre-operative scores based on patient characteristics are commonly used to predict hip fracture outcomes. Mobility, an indicator of...
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Clinical records anonymisation and text extraction (CRATE): an open-source software system
BackgroundElectronic medical records contain information of value for research, but contain identifiable and often highly sensitive confidential...
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Medicine in older age—perception and assessment of ageing processes by older people and medical and nursing professionals: study protocol for a qualitative focus group design (FOR TiMed_Life)
BackgroundThis study is conducted by a subproject of the DFG research group "Medicine, Time and the Good Life" FOR 5022 (FOR TiMed_Life) and...
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Patient and public involvement to inform priorities and practice for research using existing healthcare data for children’s and young people’s cancers
BackgroundIn the United Kingdom, healthcare data is collected on all patients receiving National Health Service (NHS) care, including children and...
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Position of the AI for Health Imaging (AI4HI) network on metadata models for imaging biobanks
A huge amount of imaging data is becoming available worldwide and an incredible range of possible improvements can be provided by artificial...
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Comparative treatment outcomes after bilateral extractions of maxillary second molars or first premolars in patients with class II malocclusion: a retrospective study
BackgroundThis retrospective cohort study aimed to compare treatment results between bilateral extraction of upper second molars (M2) and first...
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Attitudes and experiences of registered diabetes specialists in using health apps for managing type 2 diabetes: results from a mixed-methods study in Germany 2021/2022
BackgroundHardly any area of application for health apps is seen to be as promising as health and lifestyle support in type 2 diabetes mellitus....
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A systematic literature review of attitudes towards secondary use and sharing of health administrative and clinical trial data: a focus on consent
BackgroundWe aimed to synthesise data on issues related to stakeholder perceptions of consent for the use of secondary data. To better understand the...
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The PD-Ballet study: study protocol for a randomised controlled single-blind hybrid type 2 clinical trial evaluating the effects of ballet dancing on motor and non-motor symptoms in Parkinson’s disease
BackgroundTo date, beneficial effects of multimodal exercise programmes on Parkinson’s disease (PD) have focused on motor symptoms and little...
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BRAVEHeart: a randomised trial comparing the accuracy of Breathe Well and RPM for deep inspiration breath hold breast cancer radiotherapy
BackgroundDeep inspiration breath hold (DIBH) reduces radiotherapy cardiac dose for left-sided breast cancer patients. The primary aim of the...
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Prediction of childhood overweight and obesity at age 10–11: findings from the Studying Lifecourse Obesity PrEdictors and the Born in Bradford cohorts
BackgroundIn England, 41% of children aged 10–11 years live with overweight or obesity. Identifying children at risk of develo** overweight or...
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Impact of PSA testing on secondary care costs in England and Wales: estimates from the Cluster randomised triAl of PSA testing for Prostate cancer (CAP)
BackgroundScreening men for prostate cancer using prostate-specific antigen (PSA) testing remains controversial. We aimed to estimate the likely...
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Children of parents with different severities of mental health conditions have higher risk of somatic morbidity: a Danish nationwide register-based cohort study
BackgroundChildren with the most severe parental mental health conditions have an elevated risk of numerous adversities including somatic morbidity....
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Guided self-help for anxiety among Huntington’s disease gene expansion carriers (GUIDE-HD) compared to treatment as usual: a randomised controlled feasibility trial
BackgroundHuntington’s disease (HD) is an adult-onset genetic neurodegenerative condition associated with cognitive decline, motor impairments, and...
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The delivery of Ask-Advise-Connect for smoking cessation in Dutch general practice during the COVID-19 pandemic: results of a pre-post implementation study
BackgroundThe Ask-Advise-Connect approach can help primary care providers to increase the number of smokers that attempt to quit smoking and enrol...
