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Vascular endothelial cell development and diversity
Vascular endothelial cells form the inner layer of blood vessels where they have a key role in the development and maintenance of the functional...
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Transcatheter Ductus Arteriosus Stenting for Acute Pediatric Pulmonary Arterial Hypertension is Associated with Improved Right Ventricular Echocardiography Strain
BackgroundInterventional therapies for severe pulmonary arterial hypertension (PAH) can provide right ventricular (RV) decompression and preserve...
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Verification of immunology-related genetic associations in BPD supports ABCA3 and five other genes
BackgroundInflammatory processes are key drivers of bronchopulmonary dysplasia (BPD), a chronic lung disease in preterm infants. In a large sample,...
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Milrinone in persistent pulmonary hypertension of newborn: a sco** review
AbstractPersistent pulmonary hypertension of the newborn (PPHN) is a common neonatal condition in newborns admitted to the neonatal intensive care...
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Impact of patent ductus arteriosus shunt size and duration on risk of death or severe respiratory morbidity in preterm infants born in China
The purpose of this study is to assess whether duration and size of the arterial duct were associated with severe respiratory morbidity and mortality...
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Identifying Patients with Group 3 Pulmonary Hypertension Associated with COPD or ILD Using an Administrative Claims Database
BackgroundGroup 3 pulmonary hypertension (PH) describes a subpopulation of patients with PH due to chronic lung disease and/or hypoxia, with chronic...
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Bronchopulmonary Dysplasia: a Multidisciplinary Approach to Management
Purpose of ReviewWe aim to present the challenges in defining bronchopulmonary dysplasia (BPD) and summarize optimized management of established BPD...
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Congenital lung malformations
Congenital lung malformations (CLMs) are rare developmental anomalies of the lung, including congenital pulmonary airway malformations (CPAM),...
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Lung UltrasouNd Guided surfactant therapy in preterm infants: an international multicenter randomized control trial (LUNG study)
BackgroundThe management of respiratory distress syndrome (RDS) in premature newborns is based on different types of non-invasive respiratory support...
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Lung Function Tests in Infants and Children
Lung function testing is an essential modality of investigation in children as it provides objective evidence of lung disease/health. With advances...
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Advances in multimodal imaging of lung injury
Lung injury is caused by various physical and chemical damages that lead to the destruction of the structural integrity or dysfunction of the lungs,...
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Neonatal cardiorespiratory imaging—a multimodality state-of-the-art review
Advanced cardiorespiratory imaging of the chest with ultrasound (US), computed tomography (CT) and magnetic resonance imaging (MRI) plays an...
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Neonatal persistent pulmonary hypertension related to a novel TBX4 mutation: case report and review of the literature
TBX4 gene, located on human chromosome 17q23.2, encodes for T-Box Transcription Factor 4, a transcription factor that belongs to the T-box gene...
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Care of the critically ill neonate with hypoxemic respiratory failure and acute pulmonary hypertension: framework for practice based on consensus opinion of neonatal hemodynamics working group
Circulatory transition after birth presents a critical period whereby the pulmonary vascular bed and right ventricle must adapt to rapidly changing...
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Neonatal interstitial lung disease in a girl with Jacobsen syndrome: a case report
BackgroundWe report a case of the neonatal interstitial lung disease pulmonary interstitial glycogenosis in a girl with Jacobsen syndrome. While...
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Carbon dioxide levels in neonates: what are safe parameters?
AbstractThere is no consensus on the optimal pCO 2 levels in the newborn. We reviewed the effects of hypercapnia and hypocapnia and existing carbon...
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Prophylactic indomethacin and the risk of serious pulmonary hemorrhages in preterm infants less than 28 weeks’ gestation
ObjectiveTo determine if prophylactic indomethacin (PINDO) decreases serious pulmonary hemorrhages in infants <28 weeks.
Study designIntention-to-tre...
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A novel approach using volumetric dynamic airway computed tomography to determine positive end-expiratory pressure (PEEP) settings to maintain airway patency in ventilated infants with bronchopulmonary dysplasia
BackgroundPositive end-expiratory pressure (PEEP) is a key mechanical ventilator setting in infants with bronchopulmonary dysplasia (BPD). Excessive...
