Search
Search Results
-
Glutamatergic synapse in autism: a complex story for a complex disorder
Autism spectrum disorder (ASD) is a neurodevelopmental disorder whose pathophysiological mechanisms are still unclear. Hypotheses suggest a role for...
-
Autism spectrum disorders and the gastrointestinal tract: insights into mechanisms and clinical relevance
Autism spectrum disorders (ASDs) are recognized as central neurodevelopmental disorders diagnosed by impairments in social interactions,...
-
Modeling SHANK3-associated autism spectrum disorder in Beagle dogs via CRISPR/Cas9 gene editing
Despite intensive studies in modeling neuropsychiatric disorders especially autism spectrum disorder (ASD) in animals, many challenges remain....
-
The relationship between communication skills, sensory difficulties, and anxiety in children with autism spectrum disorder
BackgroundDespite the high prevalence of communicational differences, anxiety, and sensory processing difficulties in children with autism spectrum...
-
Early-life differences in the gut microbiota composition and functionality of infants at elevated likelihood of develo** autism spectrum disorder
Evidence from cross-sectional human studies, and preliminary microbial-based intervention studies, have implicated the microbiota-gut-brain axis in...
-
Is medical home care adequacy associated with educational service use in children and youth with autism spectrum disorder (ASD)?
BackgroundThe American Academy of Pediatrics (AAP) recommends medical home care for children and youth with autism spectrum disorder (ASD) for health...
-
Factors predicting depressive symptoms in parents of children with autism spectrum disorder in eastern China
BackgroundParents of children with autism spectrum disorder (ASD) are at a higher risk of depression than parents of typically develo** children...
-
Predictors of placebo response in three large clinical trials of the V1a receptor antagonist balovaptan in autism spectrum disorder
High rates of placebo response are increasingly implicated in failed autism spectrum disorder (ASD) clinical trials. Despite this, there are limited...
-
Granulocyte macrophage colony-stimulating factor-induced macrophages of individuals with autism spectrum disorder adversely affect neuronal dendrites through the secretion of pro-inflammatory cytokines
BackgroundA growing body of evidence suggests that immune dysfunction and inflammation in the peripheral tissues as well as the central nervous...
-
From bench to bedside: The mGluR5 system in people with and without Autism Spectrum Disorder and animal model systems
The metabotropic glutamate receptor 5 (mGluR5) is a key regulator of excitatory (E) glutamate and inhibitory (I) γ-amino butyric acid (GABA)...
-
Current and future applications of light-sheet imaging for identifying molecular and developmental processes in autism spectrum disorders
Autism spectrum disorder (ASD) is identified by a set of neurodevelopmental divergences that typically affect the social communication domain. ASD is...
-
Individual brain regulation as learned via neurofeedback is related to affective changes in adolescents with autism spectrum disorder
BackgroundEmotions often play a role in neurofeedback (NF) regulation strategies. However, investigations of the relationship between the induced...
-
Biological correlates of altered circadian rhythms, autonomic functions and sleep problems in autism spectrum disorder
Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by a complex and multifaceted neurobehavioral syndrome. In the last...
-
Translating neuroimaging changes to neuro-endophenotypes of autistic spectrum disorder: a narrative review
BackgroundAutism-spectrum disorder is a neurodevelopmental disorder with heterogeneity in etiopathogenesis and clinical presentation. Neuroanatomical...
-
Two-year follow-up of 90 children with autism spectrum disorder receiving intensive developmental play therapy (3i method)
BackgroundThe Intensive, Interactive, and Individual (3i) intervention approach aims to decrease the severity of autism spectrum disorder (ASD) using...
-
Predicting diagnostic outcome in adult autism spectrum disorder using the autism diagnostic observation schedule, second edition
BackgroundThe Autism Diagnostic Observation Schedule, Second Edition (ADOS-2) module four assessment for diagnosing autism spectrum disorder in...
-
Autism spectrum disorder in a boy with congenital insensitivity to pain with anhidrosis: a case report
BackgroundIn this case report, we described the past history, clinical manifestations, genetic characteristics and cognitive evaluation of a boy with...
-
Evidence of transgenerational effects on autism spectrum disorder using multigenerational space-time cluster detection
BackgroundTransgenerational epigenetic risks associated with complex health outcomes, such as autism spectrum disorder (ASD), have attracted...
-
Salivary testosterone in male and female youth with and without autism spectrum disorder: considerations of development, sex, and diagnosis
BackgroundPuberty is characterized by significant physical, hormonal, and psychological changes, which may be especially challenging for individuals...
