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Complications of spine surgery for metastasis
The spinal column represents the third most common site for metastases after the lungs and the liver, and the most common site for metastatic bone...
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Impact of oversedation prevention in ventilated critically ill patients: a randomized trial—the AWARE study
BackgroundAlthough oversedation has been associated with increased morbidity in ventilated critically ill patients, it is unclear whether prevention...
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Intra-abdominal sepsis: new definitions and current clinical standards
PurposeThe abdomen is the second most common source of sepsis and is associated with unacceptably high morbidity and mortality. Recently, the...
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Evolving Trend of EVLP: Advancements and Emerging Pathways
Lung transplant augmentation in the waiting list is impeded by donor lung shortage with a low percentage of procurement. Ex vivo lung perfusion...
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Management of choroid plexus tumors—an institutional experience
BackgroundChoroid plexus tumors are rare entities. Resection is the mainstay of treatment in grade I and grade II tumors and adjuvant treatment is...
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Pressure support ventilation + sigh in acute hypoxemic respiratory failure patients: study protocol for a pilot randomized controlled trial, the PROTECTION trial
BackgroundAdding cyclic short sustained inflations (sigh) to assisted ventilation yields optimizes lung recruitment, decreases heterogeneity and...
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Improved short- and long-term outcome of allogeneic stem cell recipients admitted to the intensive care unit: a retrospective longitudinal analysis of 942 patients
PurposeIntensive care unit (ICU) admission of allogeneic hematopoietic stem cell transplant (HSCT) recipients is associated with relatively poor...
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The standard of care of patients with ARDS: ventilatory settings and rescue therapies for refractory hypoxemia
PurposeSevere ARDS is often associated with refractory hypoxemia, and early identification and treatment of hypoxemia is mandatory. For the...
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Severe hypercapnia and outcome of mechanically ventilated patients with moderate or severe acute respiratory distress syndrome
PurposeTo analyze the relationship between hypercapnia develo** within the first 48 h after the start of mechanical ventilation and outcome in...
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Sepsis in the burn patient: a different problem than sepsis in the general population
Sepsis has recently been defined as “life-threatening organ dysfunction caused by a dysregulated host response to infection”. A great amount of...
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Treatment of Complications from Immune Checkpoint Inhibition in Patients with Lung Cancer
Immune checkpoint inhibitors have revolutionized the management of advanced NSCLC. With the intention of generating an anti-tumor immune response,...
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Intravenous fluid therapy in critically ill adults
Intravenous fluid therapy is one of the most common interventions in acutely ill patients. Each day, over 20% of patients in intensive care units...
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Guidelines for Perioperative Care in Esophagectomy: Enhanced Recovery After Surgery (ERAS®) Society Recommendations
IntroductionEnhanced recovery after surgery (ERAS) programs provide a format for multidisciplinary care and has been shown to predictably improve...
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The intensive care medicine research agenda on septic shock
Septic shock remains a global health challenge with millions of cases every year, high rates of mortality and morbidity, impaired quality of life...
