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Retrospective real-world analysis of adherence and persistence to lipid-lowering therapy in Germany
BackgroundCardiovascular disease is the leading cause of mortality in Germany. Cardiovascular risk can be mitigated with long-term lipid-lowering...
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Lipid Lowering Drugs in Acute Coronary Syndromes (ACS)
Purpose of ReviewThe purpose of this review is to critically discuss whether more aggressive lipid-lowering strategies are needed in patients with...
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Rhabdomyolysis with Co-Administration of Statins and Antiplatelet Therapies—Analysis of the WHO Pharmacovigilance Database
PurposeWhile statins and antiplatelet therapies are largely prescribed together worldwide, limited information is available on the safety of their...
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Heart transplantation and human immunodeficiency virus–navigating drug-drug interactions: a case report
BackgroundAntiretroviral therapy (ART) has led to a decline in human immunodeficiency virus (HIV)-related mortality, but comorbidities, including...
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Bempedoic Acid: for Whom and When
Purpose of ReviewThe aim of creating an orally active non-statin cholesterol-lowering drug was achieved with bempedoic acid, a small linear molecule...
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RSSDI consensus recommendations for dyslipidemia management in diabetes mellitus
Diabetic dyslipidemia is characterised by low HDL-C and high triglyceride levels. Unlike the Caucasian population, though LDL-C levels are not very...
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Detection of statin-induced rhabdomyolysis and muscular related adverse events through data mining technique
Background and objectiveRhabdomyolysis (RM) is a life-threatening adverse drug reaction in which statins are the one commonly related to RM. The...
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Factors Associated with Statin Discontinuation Following Metabolic and Bariatric Surgery: A Retrospective Analysis of 2012–2021 Electronic Medical Records Network Data
Abstract BackgroundBariatric surgery has been shown to improve hyperlipidemia, decreasing the need for statin medications. Although maintaining...
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Association between triglyceride glucose index and all-cause mortality in patients with cerebrovascular disease: a retrospective study
BackgroundTriglyceride glucose (TyG) is associated with stroke, atherosclerosis, and adverse clinical outcomes. However, its correlation with...
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Cognitive Function with PCSK9 Inhibitors: A 24-Month Follow-Up Observational Prospective Study in the Real World—MEMOGAL Study
IntroductionThe cognitive safety of monoclonal antibody proprotein convertase subtilisin/kexin type 9 inhibitors (PCSK9i) has been established in...
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Time-varying and dose-dependent effect of long-term statin use on risk of type 2 diabetes: a retrospective cohort study
BackgroundWe evaluated the effect of statin use on new-onset type 2 diabetes among individuals without atherosclerotic cardiovascular disease (ASCVD)...
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Lipid goal attainment in diabetes mellitus patients after acute coronary syndrome: a subanalysis of Dyslipidemia International Study II-China
BackgroundLipid management with a low-density lipoprotein cholesterol (LDL-C) goal of < 1.4 mmol/L is recommended for patients with acute coronary...
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Statins and Gliomas: A Systematic Review of the Preclinical Studies and Meta-Analysis of the Clinical Literature
BackgroundGliomas represent most common primary brain tumors. Glioblastoma (GBM) is the most common subtype and carries a poor prognosis. There is...
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With Current Safety and Efficacy Data, Should Statins Be Made Available as Nonprescription Over-the-Counter Drugs?
Purpose of ReviewStatins inhibit the enzyme 3-hydroxy-3-methylglutaryl-coenzyme A reductase in the liver and reduce atherosclerotic cardiovascular...
