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Vagus nerve stimulation: Can it be used in adolescents or children with treatment-resistant depression?
Vagus nerve stimulation (VNS) therapy has been approved by the US Food and Drug Administration for treatment-resistant depression in patients 18...
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Technology Insight: neuroengineering and epilepsy—designing devices for seizure control
Despite substantial innovations in antiepileptic drug therapy over the past 15 years, the proportion of patients with uncontrolled epilepsy has not...
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Evaluation of interactions between cannabinoid compounds and diazepam in electroshock-induced seizure model in mice
Several studies have shown that cannabinoids have anticonvulsant properties that are mediated through activation of the cannabinoid CB1 receptors. In...
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Treatment of cerebellar masses
Cerebellar masses are a heterogenous group of conditions that can cause compression of the aqueduct or fourth ventricle, resulting in obstructive...
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Use of Second-Generation Antiepileptic Drugs in the Pediatric Population
Epilepsy is common in the pediatric population. Nine second-generation antiepileptic drugs have been approved in the US for use in epilepsy over the...
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Sedation in the neurologic intensive care unit
Providing adequate sedation in the neurologic intensive care unit (ICU) depends on determination of proper goals for sedation, adequate assessment of...
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Tardive Oculogyric Crisis during Treatment with Clozapine
Tardive oculogyric crisis (OGC) is a dystonic syndrome that starts after long-term use of dopamine receptor antagonists. Atypical antipsychotics have...
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Attenuation of the Effects of Corticosteroids on Declarative Memory with Lamotrigine
An extensive animal literature suggests that excessive corticosteroid exposure is associated with changes in memory and the hippocampus. Agents that...
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Treatment outcomes and dose-volume histogram analysis of simultaneous integrated boost method for malignant gliomas using intensity-modulated radiotherapy
BackgroundThe aim of this article is to report the treatment outcomes, toxicities, and dosimetric feasibility of our simultaneous-boost...
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Interactions between tiagabine and conventional antiepileptic drugs in the rat model of complex partial seizures
This study evaluated the interactions between tiagabine (TGB) and three conventional antiepileptic drugs (AEDs): valproate (VPA), carbamazepine...
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Will Increasing Folic Acid in Fortified Grain Products Further Reduce Neural Tube Defects without Causing Harm?: Consideration of the Evidence
To reduce neural tube defects (NTDs), the U.S. Food and Drug Administration (FDA) mandated that by January 1998 all enriched grain products should...
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Influence of aminophylline on the anticonvulsive action of gabapentin in the mouse maximal electroshock seizure threshold model
Accumulating evidence indicates that aminophylline [theophylline 2 · ethylenediamine] markedly attenuates the anticonvulsant action of conventional...
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Treatment options in acute porphyria, porphyria cutanea tarda, and erythropoietic protoporphyria
The porphyrias are a group of uncommon metabolic diseases caused by enzyme deficiencies within heme biosynthesis that lead to neurotoxic or...
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Levetiracetam for the treatment of hot flashes: a phase II study
Goals of workThe objectives of this pilot trial were to assess the potential efficacy and safety of levetiracetam for the treatment of hot flashes, a...
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Etiology and management of refractory epilepsies
The epilepsies are an important, common and diverse group of symptom complexes characterized by recurrent spontaneous seizures. Although many...
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Use of the newer antiepileptic drugs in pediatric epilepsies
Children with epilepsy, particularly infants, differ from adults not only in the clinical manifestations of their seizures but also in the presence...