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Do regular morbidity and mortality conferences reduce preventable death rates? Our experience at Princess Marina Hospital
BackgroundThe role of morbidity and mortality conferences (M&MC) in surgical departments is to provide education and improve patient care. However,...
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Performance of postmortem CT in the diagnosis of natural death from out-of-hospital cardiac arrest
PurposePostmortem CT (PMCT) is used widely to identify the cause of death. However, its diagnostic performance in cases of natural death from...
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The use of quantitative pupillometry in brain death determination: preliminary findings
PurposeQuantitative pupillometry (QP) has been increasingly applied in neurocritical care as an easy-to-use and reliable technique for evaluating the...
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Rationale for revisions to the definition of death and criteria for its determination in Canada
Clarity regarding the biomedical definition of death and the criteria for its determination is critical to inform practices in clinical care, medical...
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Fatal child abuse detected by systematic post-mortem fundus photograph in sudden death in infancy
In living children, the use of a wide field fundus camera such as RetCam is the gold standard practice to document retinal haemorrhages in suspected...
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The role of cell death in SARS-CoV-2 infection
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), showing high infectiousness, resulted in an ongoing pandemic termed coronavirus disease...
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Is a History of Seizures an Important Risk Factor for Sudden Cardiac Death in Young Athletes?
Purpose of ReviewThis review examines the significance of seizures in young athletes and the complex inter-relationship between seizures, epilepsy,...
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Apnea Testing on Conventional Mechanical Ventilation During Brain Death Evaluation
IntroductionThe use of continuous positive airway pressure has been shown to improve the tolerance of the apnea test, a critical component of brain...
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Brainstem neuropathology in two cases of COVID-19: SARS-CoV-2 trafficking between brain and lung
IntroductionSARS-CoV-2 might spread through the nervous system, reaching respiratory centers in the brainstem. Because we recently reported...
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Diagnostic accuracy of ancillary tests for death by neurologic criteria: a systematic review and meta-analysis
PurposeAncillary tests are frequently used in death determination by neurologic criteria (DNC), particularly when the clinical neurologic examination...
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Brain MRI imaging markers associated with death in children with central nervous system involvement of hemophagocytic lymphohistiocytosis
ObjectivesTo investigate the association of brain MRI and clinical variables with death in children with central nervous system involvement of...
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Identification of patients at high risk for brain death using an automated digital screening tool: a prospective diagnostic accuracy study
BackgroundAn automated digital screening tool (DETECT) has been developed to aid in the early identification of patients who are at risk of...
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A Taxonomy of Objections to Brain Death Determination
Family objections to evaluating a patient for death by neurologic criteria, or “brain death,” are challenging for the family and the medical team. In...
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Death following rapidly progressive demyelinating disorder in a young female—a case report
Multiple sclerosis (MS) is a debilitating, demyelinating disease of the central nervous system, with manifestations ranging from numbness and...
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A case of unexpected death due to primary angiitis of the central nervous system
Primary angiitis of the central nervous system (PACNS) is a rare and fatal cerebral vasculitis mainly involving the arteriole of the pia mater,...
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Ancillary investigations for death determination in infants and children: a systematic review and meta-analysis
PurposeWe performed a systematic review and meta-analysis to determine the diagnostic test accuracy of ancillary investigations for declaration of...
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Cerebral blood vessels and perfusion in the pediatric brain death: five cases studied by neuroimaging
PurposeTo detect the cerebral blood vessels and perfusion using neuroimaging modalities including computed tomography angiography (CTA), computed...
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A brain-based definition of death and criteria for its determination after arrest of circulation or neurologic function in Canada: a 2023 clinical practice guideline
This 2023 Clinical Practice Guideline provides the biomedical definition of death based on permanent cessation of brain function that applies to all...
