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The Impact of Aging on Multiple Sclerosis
Purpose of ReviewMultiple sclerosis (MS) is a chronic, immune-mediated demyelinating disorder of the central nervous system. Age is one of the most...
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Association between adiposity and facial aging: results from a Mendelian randomization study
BackgroundSkin, as a sociologically meaningful interface, has psychological implications different from other organs, particularly in the context of...
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Immunophenotypes in psychosis: is it a premature inflamm-aging disorder?
Immunopsychiatric field has rapidly accumulated evidence demonstrating the involvement of both innate and adaptive immune components in psychotic...
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Getting old in the desired gender: a systematic review on aging diseases in transgender people
IntroductionThe growing demographic presence of the transgender (TGD) population has sparked an increase in clinical investigations focusing on the...
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GWAS of biological aging to find longevity genes in schizophrenia
Schizophrenia (SCZ) is a severe psychotic disorder associated with premature mortality and aging. Moreover, the symptoms and progression of...
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Trauma, adversity, and biological aging: behavioral mechanisms relevant to treatment and theory
Although stress and adversity are largely universal experiences, people exposed to greater hardship are at increased risk for negative health...
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Aging endometrium in young women: molecular classification of endometrial aging-based markers in women younger than 35 years with recurrent implantation failure
BackgroundTo explore the differences between a population with premature endometrial aging and a population with normal endometrial status in young...
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Mechanisms of Neurocognitive Adaptation during Aging Process
AbstractHuman aging is associated with an increased risk of various geriatric syndromes, cognitive impairment being among the most frequent. The most...
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Glucose-6-phosphate dehydrogenase deficiency accelerates arterial aging in diabetes
AimsHigh glucose levels and Glucose-6-Phosphate Dehydrogenase deficiency (G6PDd) have both tissue inflammatory effects. Here we determined whether...
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Posttraumatic stress disorder, trauma, and accelerated biological aging among post-9/11 veterans
People who experience trauma and develop posttraumatic stress disorder (PTSD) are at increased risk for poor health. One mechanism that could explain...
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Nutrition and Healthy Aging: A Review
Purpose of ReviewThe review attempts to highlight various dietary approaches for healthy aging; it examines the current evidence regarding the impact...
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Non-neoplastic disorders in an aging gut: concise review
The spectrum of gastrointestinal (GI) issues in the older population varies from common physiological age-related changes to devastating, less common...
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Cognitive flexibility's role in sha** self-perception of aging, body appreciation, and self-efficacy among community-dwelling older women
BackgroundCognitive flexibility, the capacity to adjust to new information, affects how aging is perceived. In Egyptian culture, older women’s views...
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Targeting the “hallmarks of aging” to slow aging and treat age-related disease: fact or fiction?
Aging is a major risk factor for a number of chronic diseases, including neurodegenerative and cerebrovascular disorders. Aging processes have...
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Transcriptional Regulation in the Control of Aging and Longevity
AbstractTranscription regulation is required for correct differential gene expression, which determines the development and function of all cells in...
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The Effects of Aging on Solid Organ Transplantation—Characteristics and Consequences of Immunosenescence
Purpose of reviewTo discuss how T, natural killer (NK), and B cell aging modifies outcomes of organ transplantation, the transplant recipient’s...
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Aging Processes Are Affected by Energy Balance: Focused on the Effects of Nutrition and Physical Activity on Telomere Length
Purpose of ReviewThe number and proportion of individuals aged 60 and over are increasing globally. The increase in the elderly population has...
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Intersectional Approaches to Minority Aging Research
Purpose of ReviewGrowing racial/ethnic diversity among America’s older adults necessitates additional research specifically focused on health and...
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Experiences of Aging with Opioid Use Disorder and Comorbidity in Opioid Treatment Programs: A Qualitative Analysis
BackgroundThe number of older adults entering opioid treatment programs (OTPs) to treat opioid use disorder (OUD) is increasing. However, the lived...
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PCLAF induces bone marrow adipocyte senescence and contributes to skeletal aging
Bone marrow adipocytes (BMAds) affect bone homeostasis, but the mechanism remains unclear. Here, we showed that exercise inhibited PCNA...