Search
Search Results
-
Distribution of brain metastases: low-risk metastasis areas may be avoided when treating with whole-brain radiotherapy
ObjectivePrevious work has demonstrated that metastases are not uniformly distributed across the brain. This study aims to determine there are...
-
The therapeutic effect of radiotherapy combined with systemic therapy compared to radiotherapy alone in patients with simple brain metastasis after first-line treatment of limited-stage small cell lung cancer: a retrospective study
PurposeWe aimed to compare the therapeutic effect of radiotherapy (RT) plus systemic therapy (ST) with RT alone in patients with simple brain...
-
Differential abscopal effect in extracranial and intracranial lesions after radiotherapy alone for vertebral bone metastasis of unknown primary: a case report
BackgroundThe abscopal effect is a phenomenon in which a tumor located far from irradiated lesions regresses. We have experienced a case in which...
-
Metronomic Chemotherapy After Palliative Radiotherapy in Rare Soft Tissue Sarcomas: An Insight into Radiation Therapy and the Immune Response
Soft tissue sarcomas (STSs) account for less than 1% of the overall human burden of malignant tumors. The intent of treatment in metastatic STSs is...
-
Reduction of immunosuppression combined with whole-brain radiotherapy and concurrent systemic rituximab is an effective yet toxic treatment of primary central nervous system post-transplant lymphoproliferative disorder (pCNS-PTLD): 14 cases from the prospective German PTLD registry
Post-transplant lymphoproliferative disorders (PTLD) exclusively affecting the central nervous system—primary CNS-PTLD (pCNS-PTLD)—are rare. There is...
-
Regional deep hyperthermia in combination with whole brain radiotherapy (WBRT) in poor prognosis patients with brain metastases
PurposeThe aim of this study is to assess for the first time, the role of regional deep hyperthermia in combination with radiotherapy and systemic...
-
Successful salvage of recurrent leptomeningeal disease in large cell neuroendocrine lung cancer with stereotactic radiotherapy
A 70-year old male with stage I large cell neuroendocrine carcinoma (LCNEC) of the lung underwent resection of a metachronous 5 cm brain metastasis...
-
A matched-pair analysis comparing stereotactic radiosurgery with whole-brain radiotherapy for patients with multiple brain metastases
IntroductionStereotactic radiosurgery (SRS) is an emerging treatment for patients with multiple brain metastases (BM). The present work compares the...
-
Stereotactic radiotherapy for brain metastases: predictive factors of radionecrosis
PurposeStereotactic radiotherapy (SRT) is a highly effective approach and represents the current standard of treatment for patients with limited...
-
Cardiac markers in left-sided breast cancer patients receiving adjuvant radiotherapy: a prospective study
ObjectivesTo investigate the association between radiotherapy (RT) and cardiac biomarkers in women with left-sided breast cancer.
Methods ... -
Neutrophils seeking new neighbors: radiotherapy affects the cellular framework and the spatial organization in a murine breast cancer model
Neutrophils are known to contribute in many aspects of tumor progression and metastasis. The presence of neutrophils or neutrophil-derived mediators...
-
Is consolidative thoracic radiotherapy of extensive-stage small cell lung cancer still beneficial in the era of immunotherapy? A retrospective analysis
PurposeExtensive-stage small cell lung cancer (ES-SCLC) carries a dismal prognosis. The benefit of consolidative thoracic radiotherapy (TR) after...
-
Intraoperative or postoperative stereotactic radiotherapy for brain metastases: time to systemic treatment onset and other patient-relevant outcomes
PurposeIntraoperative radiotherapy (IORT) has become a viable treatment option for resectable brain metastases (BMs). As data on local control and...
-
Palliative appropriateness criteria: external validation of a new method to evaluate the suitability of palliative radiotherapy fractionation
BackgroundRecently, the palliative appropriateness criteria (PAC) score, a novel metric to aid clinical decision-making between different palliative...
-
Intracranial intraoperative radiotherapy (IORT): evaluation of electrocorticography and peri-operative seizure risk
BackgroundIntra-operative radiotherapy (IORT) for brain metastases (BMs) and primary brain tumors has emerged as an adjuvant radiation modality that...
-
Role of resting-state functional MRI in detecting brain functional changes following radiotherapy for head and neck cancer: a systematic review and meta-analysis
PurposeIncreasing evidence implicates changes in brain function following radiotherapy for head and neck cancer as precursors for brain dysfunction....
-
Whole brain radiotherapy improves survival outcomes in primary CNS lymphoma patients ineligible for systemic therapy
PurposePrimary central nervous system lymphoma (PCNSL) is a very rare type of malignancy with a poor prognosis. The role of whole brain radiotherapy...
-
Platinum-based adjuvant chemoradiotherapy versus adjuvant radiotherapy in patients with head and neck adenoid cystic carcinoma
PurposeThe objective of the study was to assess the effectiveness and toxicity of platinum-based adjuvant chemoradiotherapy (POCRT) in comparison to...
-
Changing trends in gamma knife surgery to linear accelerator brain stereotactic radiotherapy in Japan: a survey based on the nationwide claims database
PurposeThis study evaluated the trends in the platform for stereotactic radiotherapy to the brain (SRT), utilizing the open data of the National...
-
Early disc degeneration in radiotherapy-treated childhood brain tumor survivors
BackgroundChildhood brain tumor (BT) survivors have an increased risk of treatment-related late effects, which can reduce health-related quality of...