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Knockdown of MRPL35 promotes cell apoptosis and inhibits cell proliferation in non-small-cell lung cancer
BackgroundNon-small cell lung cancer (NSCLC) is a major pathological type of lung cancer. However, its pathogenesis remains largely unclear. MRPL35...
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Radiological evidence of rapid growth acceleration of a small part solid nodule found to be large-cell carcinoma of the lung
BackgroundWith the widespread use of low-dose computed tomography for lung cancer screening, the detection rate of pulmonary lesions manifesting as...
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Small cell carcinoma presenting as a biatrial mass with obstructive physiology: a case report
BackgroundSmall cell carcinoma is a highly aggressive and often fatal cancer that most commonly arises in the lung, although it can occasionally...
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Desmoplastic small round cell tumor of the liver: diagnosing a rare case on liver biopsy
Desmoplastic small round-cell tumors (DSRCT) frequently develop in the retroperitoneum, pelvis, omentum, and mesentery. Here, we present an unusual...
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The rs1801280 SNP is associated with non-small cell lung carcinoma by exhibiting a highly deleterious effect on N-acetyltransferase 2
PurposeN-acetyltransferase 2 is an enzyme that is involved in the detoxification of carcinogens in the human body, so any damage to this protein may...
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The clinical significance of integrin subunit alpha V in cancers: from small cell lung carcinoma to pan-cancer
BackgroundLittle is known about the relationship between integrin subunit alpha V ( ITGAV ) and cancers, including small cell lung cancer (SCLC).
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Multi-task learning-based histologic subtype classification of non-small cell lung cancer
PurposeIn clinical applications, accurate histologic subtype classification of lung cancer is important for determining appropriate treatment plans....
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CRL2KLHDC3 mediates p14ARF N-terminal ubiquitylation degradation to promote non-small cell lung carcinoma progression
Kelch superfamily involves a variety of proteins containing multiple kelch motif and is well characterized as substrate adaptors for CUL3 E3 ligases,...
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Mandibular small cell osteosarcoma: a case report and review of literature
BackgroundSmall cell osteosarcoma is an extremely rare histopathological variant of conventional osteosarcoma. Due to nonspecific symptoms, most...
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Histological Subtype Classification of Non-Small Cell Lung Cancer with Radiomics and 3D Convolutional Neural Networks
Non-small cell lung carcinoma (NSCLC) is the most common type of pulmonary cancer, one of the deadliest malignant tumors worldwide. Given the...
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Women are Underrepresented in Non-small Cell Lung Cancer Clinical Trials: A Systematic Review
PurposeTo perform a systematic review of clinical trials examining non-small cell lung cancer (NSCLC) to better understand the equity afforded to...
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Small Round Blue Cell Tumours of the Sinonasal Area: Our 5 year Experience in a Tertiary Care Centre in India
Purpose: The main purpose of this study is to understand the characteristics and management of sinonasal small round blue cell tumors and also to...
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Comparison of segmentectomy and wedge resection for cT1cN0M0 non-small cell lung cancer
ObjectiveSublobar resection is considered a standard surgical procedure for early non-small cell lung cancer, although the survival of patients...
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Unresected small lymph node assessment predicts prognosis for patients with pT3N0M0 thoracic esophageal squamous cell carcinoma
BackgroundThe role of unresected small lymph nodes (LNs) which may contain metastases for thoracic esophageal squamous cell carcinoma (TESCC) has not...
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Predictors of lung cancer subtypes and lymph node status in non-small-cell lung cancer: intravoxel incoherent motion parameters and extracellular volume fraction
ObjectiveTo determine the performance of intravoxel incoherent motion (IVIM) parameters and the extracellular volume fraction (ECV) in distinguishing...
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Genomic profiling of NGS-based ctDNA from Chinese non-small cell lung cancer patients
PurposeCell-free circulating tumor DNA (ctDNA) in plasma enables rapid and repeat testing of actionable mutations. Next-generation sequencing (NGS)...
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Small cell-like change in prostatic adenocarcinoma and intraductallesions – neuroendocrine or not?
BackgroundSmall cell-like change in prostatic neoplasia (both invasive adenocarcinoma and intraepithelial lesions) is described in three previous...
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Genetic and immunohistochemical profiling of small cell and large cell neuroendocrine carcinomas of the breast
Neuroendocrine carcinomas (NEC) of the breast are exceedingly rare tumors, which are classified in the WHO system as small cell (SCNEC) and large...
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Prospective evaluation of the diagnostic efficacy of multiparametric MRI clear cell Likelihood Score in small solid renal masses and its predictive value for tumor grade
BackgroundThe detection of small renal masses has significantly increased due to the widespread use of cross-sectional imaging in recent years. Among...
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Prospects of microRNAs as therapeutic biomarkers in non-small cell lung cancer
Lung Cancer, the second most common cancer worldwide, remains the leading cause of cancer-related deaths, contemporarily. More than 85% of identified...
