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Melody transcatheter pulmonary valve replacement: a single-center case series in Southeast Asia
BackgroundStudies of transcatheter pulmonary valve replacement (TPVR) with the Melody valve have demonstrated good clinical and hemodynamic outcomes....
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Maternal early exposure to violence, psychopathology, and child adaptive functioning: pre- and postnatal programming
BackgroundThe pre- and postnatal programming mechanisms, timing, and direction of effects linking maternal early exposure to violence (MEEV),...
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TGFβ1-RCN3-TGFBR1 loop facilitates pulmonary fibrosis by orchestrating fibroblast activation
BackgroundIdiopathic pulmonary fibrosis (IPF) bears high mortality due to unclear pathogenesis and limited therapeutic options. Therefore,...
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Clinical course of COPD patients with exercise-induced elevation of pulmonary artery pressure or less severe pulmonary hypertension presenting with respiratory symptoms and the impact of bosentan intervention—prospective, single-center, randomized, parallel-group study
BackgroundThe data on bosentan were lacking for the treatment of exercise-induced elevation of pulmonary artery pressure (eePAP) or less severe PH in...
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Evaluation of rheumatoid arthritis and connective tissue disease-related interstitial lung disease with pulmonary physiologic test, HRCT, and patient-based measures of dyspnea and functional disability
ObjectivesWe aim to investigate the relationship between pulmonary function and imaging parameters with symptom-related patient-reported outcome...
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Can a novel drug dose be used for T3 suppression test?
PurposeThis study aimed to investigate whether 25 µg/day dose of triiodothyronine (T3) can also suppress thyroid stimulating hormone (TSH) level, as...
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An observational cohort study on pulmonary function in adult patients with 5q-spinal muscular atrophy under nusinersen therapy
BackgroundFew studies assessed the effect of nusinersen on respiratory function in adult patients with spinal muscular atrophy (SMA). The aim of this...
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Family functioning and health-related quality of life of inpatients with coronary heart disease: a cross-sectional study in Lanzhou city, China
BackgroundA key outcome in coronary heart disease (CHD) is Health Related Quality of Life (HRQoL), and family functioning is important in the...
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Current and Future Treatment Landscape for Idiopathic Pulmonary Fibrosis
Idiopathic pulmonary fibrosis (IPF) remains a disease with poor survival. The pathogenesis is complex and encompasses multiple molecular pathways....
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Significant role of circRNA BBS9 in chronic obstructive pulmonary disease via miRNA-103a-3p/BCL2L13
BackgroundVarious studies have shown that circular RNA (circRNA) plays a pivotal role in chronic obstructive pulmonary disease (COPD). We aimed to...
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Effectiveness of home-based pulmonary rehabilitation programs for patients with chronic obstructive pulmonary disease (COPD): systematic review
BackgroundAlthough pulmonary rehabilitation (PR) is considered a key component in managing chronic obstructive pulmonary disease (COPD) patients,...
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Respiratory morbidity in preschool and school-age children born very preterm and its association with parents’ health-related quality of life and family functioning
The purpose of this study is to describe the prevalence and severity of respiratory symptoms in children born very preterm and to assess their...
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Self-reported physical functioning, cardiometabolic health conditions, and health care utilization patterns in Million Veteran Program enrollees with Traumatic Brain Injury Screening and Evaluation Program data
BackgroundExamining the health outcomes of veterans who have completed the United States Veterans Health Administration’s (VHA’s) Traumatic Brain...
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Complete thoracoscopic S9 and/or S10 segmentectomy through a pulmonary ligament approach: a retrospective study
BackgroundThe high resolution of computed tomography has found the pulmonary ligaments that consists of a double serous layer of visceral pleura,...
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Role of thioredoxin in chronic obstructive pulmonary disease (COPD): a promising future target
IntroductionThioredoxin (Trx) is a secretory protein that acts as an antioxidant, redox regulator, anti-allergic, and anti-inflammatory molecule. It...
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Low cognitive functioning and depressive symptoms in patients with rheumatoid arthritis and systemic sclerosis: a clinical study
BackgroundRecently, cognitive deficits occurring in rheumatic diseases have attracted scientific attention. Cognitive symptoms in patients with...
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Understanding contextual and practical factors to inform WHO recommendations on using chest imaging to monitor COVID-19 pulmonary sequelae: a qualitative study exploring stakeholders’ perspective
BackgroundA recommendation by the World Health Organization (WHO) was issued about the use of chest imaging to monitor pulmonary sequelae following...
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LncRNAH19 acts as a ceRNA of let-7 g to facilitate endothelial-to-mesenchymal transition in hypoxic pulmonary hypertension via regulating TGF-β signalling pathway
BackgroundHypoxic pulmonary hypertension (HPH) is a challenging lung arterial disorder with remarkably high incidence and mortality rates, and the...
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Cut-off values of 6-min walk test and sit-to-stand test for determining symptom burden in atrial fibrillation
BackgroundSince symptomatology is a major predictor of quality of life and an endpoint for the management of atrial fibrillation (AF), practical...
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Comparing the effects of smartphone-based and face-to-face pulmonary rehabilitation education on caregiver burden and quality of life among the family caregivers of patients with chronic obstructive pulmonary disease: a randomized controlled field trial
BackgroundFunctional limitation among patients with chronic obstructive pulmonary disorder (COPD) and their dependence on their family caregivers...
