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Prostate-specific membrane antigen-positron emission tomography (PSMA-PET) of prostate cancer: current and emerging applications
Prostate-specific membrane antigen-positron emission tomography (PSMA-PET) is transforming the management of patients with prostate cancer. In...
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Prostate cancer screening—step** forward with MRI
Abstract ObjectiveTo comprehensively review the literature on the integration of MRI as a diagnostic tool in prostate cancer screening and offer...
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Updates on Management of Biochemical Recurrent Prostate Cancer
Patients with biochemical recurrent prostate cancer (BCR) are a heterogeneous group, whereby a personalized approach to management is critical....
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A nomogram based on biparametric magnetic resonance imaging for detection of clinically significant prostate cancer in biopsy-naïve patients
PurposeThis study aimed to develop and validate a model based on biparametric magnetic resonance imaging (bpMRI) for the detection of clinically...
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The potential role of the microbiota in prostate cancer pathogenesis and treatment
The human body hosts a complex and dynamic population of trillions of microorganisms — the microbiota — which influences the body in homeostasis and...
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Causal relationship between gut microbiota and prostate cancer contributes to the gut-prostate axis: insights from a Mendelian randomization study
BackgroundChanges in gut microbiota abundance have been linked to prostate cancer development. However, the causality of the gut-prostate axis...
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Prostate cancer biomarkers: from early diagnosis to precision treatment
Prostate cancer (PCa) is the second most prevalent cancer in men. In 2020, approximately 1,414,259 new cases were reported that accounted for...
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Update on prostate cancer epidemiology in Morocco
BackgroundProstate cancer stands as the most frequently diagnosed cancer among men globally, with over 600,000 new cases annually. In-depth...
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Simultaneous thulium laser resection of the prostate and transperineal prostate biopsy in clinically diagnosed metastatic prostate cancer with bladder outlet obstruction
Metastatic prostate cancer (mPCa) patients complicated with bladder outlet obstruction (BOO) are often referred to a urologist. Androgen deprivation...
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Key learning on the promise and limitations of MRI in prostate cancer screening
AbstractMRI retains its ability to reduce the harm of prostate biopsies by decreasing biopsy rates and the detection of indolent cancers in...
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Unlocking ferroptosis in prostate cancer — the road to novel therapies and imaging markers
Ferroptosis is a distinct form of regulated cell death that is predominantly driven by the build-up of intracellular iron and lipid peroxides....
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Cancer associated fibroblast secreted miR-432-5p targets CHAC1 to inhibit ferroptosis and promote acquired chemoresistance in prostate cancer
Prostate cancer (PCa) ranks as the sixth most serious male malignant disease globally. While docetaxel (DTX) chemotherapy is the standard treatment...
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The role of multiparametric ultrasound in the detection of clinically significant prostate cancer
PurposeTransrectal ultrasound (US) imaging is paramount to the successful completion of prostate biopsies. Certain US features have been associated...
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Total-body [68 Ga]Ga-PSMA-11 PET/CT improves detection rate compared with conventional [68 Ga]Ga-PSMA-11 PET/CT in patients with biochemical recurrent prostate cancer
PurposeThe purpose of this study was to assess whether total-body [ 68 Ga]Ga-PSMA-11 PET/CT could improve the detection rate compared with...
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Deep learning-based artificial intelligence for prostate cancer detection at biparametric MRI
PurposeTo present fully automated DL-based prostate cancer detection system for prostate MRI.
MethodsMRI scans from two institutions, were used for...
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Persistent organic pollutants promote aggressiveness in prostate cancer
Increasing evidence points towards a causal link between exposure to persistent organic pollutants (POPs) with increased incidence and aggressivity...
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Biparametric MRI in prostate cancer during active surveillance: is it safe?
AbstractActive surveillance (AS) is the preferred option for patients presenting with low-intermediate-risk prostate cancer. MRI now plays a crucial...
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Evaluating the value of 18F-PSMA-1007 PET/CT in the detection and identification of prostate cancer using histopathology as the standard
BackgroundProstate-specific membrane antigen (PSMA) PET/CT is a highly regarded radionuclide imaging modality for prostate cancer (PCa). This study...
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Diagnostic performance of regional systematic biopsy for prostate cancer stratified by PI-RADS and histologic zones
ObjectivesTo explore the diagnostic performance of targeted biopsy (TB) combined with regional systematic biopsy (RSB) in patients with different...
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Optimizing multiparametric magnetic resonance imaging-targeted biopsy and detection of clinically significant prostate cancer: the role of core number and location
PurposeThere is currently no consensus regarding the optimal number of multiparametric magnetic resonance imaging (MRI)-targeted biopsy (TB) cores...