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An early screening model for preeclampsia: utilizing zero-cost maternal predictors exclusively
To provide a reliable, low-cost screening model for preeclampsia, this study developed an early screening model in a retrospective cohort (25,709...
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Is artificial endometrial preparation more associated with early-onset or late-onset preeclampsia after frozen embryo transfer?
PurposeTo explore whether the risks of early- or late-onset preeclampsia vary among frozen embryo transfer (FET) with different regimens for...
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New medicines for spontaneous preterm birth prevention and preterm labour management: landscape analysis of the medicine development pipeline
BackgroundThere are few medicines in clinical use for managing preterm labor or preventing spontaneous preterm birth from occurring. We previously...
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Increased Risk of Preeclampsia with Assisted Reproductive Technologies
Purpose of ReviewWe summarized recent available data to assess the association between assisted reproductive technology (ART) and risk for...
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Can placental shear wave elastography predict preeclampsia in high-risk pregnant women during second trimester? Insights from a prospective cohort study
BackgroundPreeclampsia, a condition very frequently linked to maternal and fetal deaths worldwide, remains a pressing concern due to delays in...
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Cholelithiasis is an additional pre-pregnancy clinical risk factor for preeclampsia
PurposeTo investigate additional potential clinical risk factors for preeclampsia.
MethodsThis is a nested case–control study of preeclampsia and...
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Paternal Expressed Gene 10 (PEG10) is decreased in early-onset preeclampsia
BackgroundPreeclampsia is a severe complication of pregnancy which is attributed to placental dysfunction. The retrotransposon, Paternal Expressed...
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Maternal Serum Cyclophilin A: A Predictive Biomarker of Preeclampsia in South Indian Women
BackgroundSerum Cyclophilin A (CyPA) is a 20 KD chaperone protein, secreted in response to oxidative stress and has an important role as mediator of...
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Advancing hypertensive disorders of pregnancy management: insights from the 5th preeclampsia scientific symposium in Ghana
The 5th Preeclampsia Scientific Symposium (PSS2023) organized by Action on Preeclampsia (APEC) Ghana was themed : ‘Realign, Refocus: Improving...
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Differences in autophagy marker levels at birth in preterm vs. term infants
BackgroundPreterm infants are susceptible to oxidative stress and prone to respiratory diseases. Autophagy is an important defense mechanism against...
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Higher PAPP-A Values in Pregnant Women Complicated with Preeclampsia Than with Gestational Hypertension
The purpose of this study is to compare the levels of maternal serum pregnancy–associated plasma protein-A at the first trimester in pregnancies...
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Comparison of the Kisspeptin levels in early onset preeclampsia and late-onset preeclampsia
ObjectiveMaternal Kisspeptin plays role in cell migration which is responsible for trophoblast invasion. We aimed to investigate the role of...
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A point-of-care urine test to predict adverse maternal and neonatal outcomes in Asian women with suspected preeclampsia
ObjectivesTo assess clinical utility of the urine Congo red dot test (CRDT) in predicting composite adverse maternal and neonatal outcomes in women...
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Potential molecular mechanisms and clinical implications of piRNAs in preeclampsia: a review
Preeclampsia is a multisystem progressive condition and is one of the most serious complications of pregnancy. Owing to its unclear pathogenesis,...
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The role of family history of preterm delivery in the individual risk of spontaneous preterm delivery: a case–control study
PurposeTo investigate the role of family history of preterm delivery (PTD) in the individual risk of spontaneous preterm delivery.
Methods ... -
Altered Cytokine Production in Human Intervillous Blood T Cells in Preeclampsia
Conventional and regulatory T cells (Treg) are dynamic mediators of maternal immune tolerance to the develo** feto-placental unit. Functional...
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Maternal anxiety forecasts shorter prolongation of pregnancies complicated by early-onset preeclampsia
PurposeIn early-onset preeclampsia, each additional day of pregnancy prolongation reduces offspring infant mortality about 9%. We evaluated if...
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Incremental predictive value of platelet parameters for preeclampsia: results from a large prospective cohort study
BackgroundPlatelet parameters during pregnancy were associated with the risk of preeclampsia (PE), but the predictive value of these parameters for...
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Autophagy-related biomarkers in preeclampsia: the underlying mechanism, correlation to the immune microenvironment and drug screening
BackgroundPreeclampsia is a life-threatening disease of pregnancy that lacks effective pharmaceuticals which can target its pathogenesis. Since...
