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Molecular mechanisms of endothelial dysfunction in coronary microcirculation dysfunction
Coronary microvascular endothelial cells (CMECs) react to changes in coronary blood flow and myocardial metabolites and regulate coronary blood flow...
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Inflammation in Coronary Atherosclerosis and Its Therapeutic Implications
Atherosclerotic coronary artery disease has a complex pathogenesis which extends beyond cholesterol intimal infiltration. It involves chronic...
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Non-contrast CT-based radiomics nomogram of pericoronary adipose tissue for predicting haemodynamically significant coronary stenosis in patients with type 2 diabetes
BackgroundType 2 diabetes mellitus (T2DM) patients have a higher incidence of coronary artery disease than the general population. The aim of this...
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Seeing is believing: pathway strategies for a personalised non-invasive diagnosis of coronary artery disease
Coronary artery disease (CAD) diagnosis requires a precise assessment of patient profile and disease extension. While non-invasive imaging modalities...
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Early microvascular coronary endothelial dysfunction precedes pembrolizumab-induced cardiotoxicity. Preventive role of high dose of atorvastatin
Immune checkpoint inhibitors (ICIs) exhibit remarkable antitumor activity and immune-related cardiotoxicity of unknown pathomechanism. The aim of the...
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Prediction of microvascular complications in diabetic patients without obstructive coronary stenosis based on peri-coronary adipose tissue attenuation model
ObjectivesTo investigate the predictive value of peri-coronary adipose tissue (PCAT) attenuation for microvascular complications in diabetic patients...
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Mechanisms of Coronary Ischemia in Women
Purpose of ReviewObstructive coronary artery disease is a major cause of ischemia in both men and women; however, women are more likely to present...
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Prognostic value of coronary CT angiography for the prediction of all-cause mortality and non-fatal myocardial infarction: a propensity score analysis
To explore the relationship between comprehensive assessment of coronary atherosclerosis by coronary CT angiography (CCTA) and all-cause mortality...
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Advanced CT measures of coronary artery disease with intermediate stenosis in patients with severe aortic valve stenosis
BackgroundCoronary artery disease (CAD) and severe aortic valve stenosis (AS) frequently coexist. While pre-transcatheter aortic valve replacement...
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SR-B1-/-ApoE-R61h/h Mice Mimic Human Coronary Heart Disease
Cardiovascular diseases are the leading cause of death in the modern world. Atherosclerosis underlies the majority of these pathologies and may...
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The Importance of Integrated Regulation Mechanism of Coronary Microvascular Function for Maintaining the Stability of Coronary Microcirculation: An Easily Overlooked Perspective
Coronary microvascular dysfunction (CMD) refers to a group of disorders affecting the structure and function of coronary microcirculation and is...
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Radiomics features of pericoronary adipose tissue improve CT-FFR performance in predicting hemodynamically significant coronary artery stenosis
ObjectivesTo evaluate the value of radiomics-based model of pericoronary adipose tissue (PCAT) combined with CT fractional flow reserve (CT-FFR) in...
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Prognostic value of CT-derived fractional flow reserve and fat attenuation index in patients with suspected coronary artery disease: a sex-disaggregated analyses
BackgroundThere are sex differences in many risk factors associated with coronary artery disease (CAD). CT-derived fractional flow reserve (CT-FFR)...
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Association between severity of nonalcoholic fatty liver disease and major adverse cardiovascular events in patients assessed by coronary computed tomography angiography
BackgroundThe effect of nonalcoholic fatty liver disease (NAFLD) on major adverse cardiovascular events (MACEs) can be influenced by the degree of...
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Circulating exosomal mir-16-2-3p is associated with coronary microvascular dysfunction in diabetes through regulating the fatty acid degradation of endothelial cells
BackgroundCoronary microvascular dysfunction (CMD) is a frequent complication of diabetes mellitus (DM) characterized by challenges in both diagnosis...
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The correlation of pericoronary adipose tissue with coronary artery disease and left ventricular function
ObjectiveWe sought to investigate the correlation of pericoronary adipose tissue with coronary artery disease and left ventricular (LV) function.
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Relationship between impaired myocardial blood flow by positron emission tomography and low-attenuation plaque burden and pericoronary adipose tissue attenuation from coronary computed tomography: From the prospective PACIFIC trial
BackgroundPositron emission tomography (PET) is the clinical gold standard for quantifying myocardial blood flow (MBF). Pericoronary adipose tissue...
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Radiomics analysis of lesion-specific pericoronary adipose tissue to predict major adverse cardiovascular events in coronary artery disease
ObjectiveTo investigate the prognostic performance of radiomics analysis of lesion-specific pericoronary adipose tissue (PCAT) for major adverse...
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Recent Advances in Coronary Computed Tomography Angiogram: The Ultimate Tool for Coronary Artery Disease
Purpose of ReviewThe emerging technologies in multidetector computed tomography scanners gave the ability to image coronary arteries in a single...
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Coronary microcirculation dysfunction evaluated by myocardial contrast echocardiography predicts poor prognosis in patients with ST-segment elevation myocardial infarction after percutaneous coronary intervention
BackgroundThe mortality rate of acute ST-segment elevation myocardial infarction (STEMI) remains substantial, despite advances in treatment...
