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Mechanical stress influences the morphology and function of human uterosacral ligament fibroblasts and activates the p38 MAPK pathway
Introduction and hypothesisPelvic organ prolapse (POP) is a common condition in older women that affects quality of life. Mechanical injury of the...
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Three-dimensional ultrastructural imaging and quantitative analysis of the periodontal ligament
The periodontal ligament (PDL) is a unique connective tissue mainly comprising collagen fiber bundles and cells between the roots of teeth and inner...
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Gestational diabetes mellitus affects the differentiation of hematopoietic stem cells in neonatal umbilical cord blood
PurposeThere are abundant hematopoietic stem cells (HSCs) in cord blood. It is known that HSCs continue to differentiate to CLP, CMP and erythroid...
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Dental Pulp-Derived Mesenchymal Stem Cells Increase Axon Numbers in Mental Nerve Repair
AimThe mental nerve, the extended part of the inferior alveolar nerve, is often injured during dentoalveolar, orthognathic, or tumor surgery....
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Nutritional Supplements and Periodontal Disease Prevention—Current Understanding
Purpose of ReviewThis review updates the current knowledge on nutrient supplements, which are reported as effective in maintaining the health of...
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LncRNA GACAT2 binds with protein PKM1/2 to regulate cell mitochondrial function and cementogenesis in an inflammatory environment
Periodontal ligament stem cells (PDLSCs) are a key cell type for restoring/regenerating lost/damaged periodontal tissues, including alveolar bone,...
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Association between lipid metabolism and periodontitis in obese patients: a cross-sectional study
BackgroundTo investigate the association between clinical periodontal parameters of periodontitis, serum lipid metabolism markers and adipokines’...
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The functional extracellular matrix on the regulation of odontogenic differentiation of stem cells
Dental defects and loss are common oral diseases that seriously affect the chewing efficiency of patients and thereby affect their health. With the...
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Prevalence of dental alterations in patients under bisphosphonates therapy: a systematic review
This systematic review aimed to estimate the prevalence and describe dentoalveolar lesions associated with bisphosphonates therapy. A systematic...
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Osteoblastic differentiation and changes in the redox state in pulp stem cells by laser treatment
The aim of this study was to determine the effect of low-level laser therapy (LLLT) on cell proliferation, mitochondrial membrane potential changes...
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Periodontal inflammation recruits distant metastatic breast cancer cells by increasing myeloid-derived suppressor cells
Periodontal diseases can lead to chronic inflammation affecting the integrity of the tooth supporting tissues. Recently, a striking association has...
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Tracking of Oral and Craniofacial Stem Cells in Tissue Development, Regeneration, and Diseases
Purpose of ReviewThe craniofacial region hosts a variety of stem cells, all isolated from different sources of bone and cartilage. However, despite...
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The Relationship Between Polycystic Ovarian Syndrome, Periodontal Disease, and Osteoporosis
Polycystic ovarian syndrome (PCOS) is the most common endocrine disorder to affect women in their reproductive years. There has been growing concern...
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RANKL and osteoimmunology in periodontitis
Periodontitis, one of the most common infectious diseases in humans, is characterized by inflammation of the periodontal tissue and subsequent...
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Periodontitis and progression of gastrointestinal cancer: current knowledge and future perspective
Periodontitis is a polymicrobial disorder caused by dysbiosis. Porphyromonas gingivalis (P.gingivalis) and Fusobacterium nucleatum (F.nucleatum) are...
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SSEA-4 positive dental pulp stem cells from deciduous teeth and their induction to neural precursor cells
BackgroundStage-specific embryonic antigen-4 (SSEA-4) is a marker for the identification of multipotent embryonic cells. It is also positive in...
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Mir-195-5p targets Smad7 regulation of the Wnt/β-catenin pathway to promote osteogenic differentiation of vascular smooth muscle cells
In this study, we sought to investigate the mechanisms of action of miR-195-5p in the osteogenic differentiation of vascular smooth muscle cells...
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M2 macrophagy-derived exosomal miRNA-26a-5p induces osteogenic differentiation of bone mesenchymal stem cells
BackgroundBone marrow mesenchymal stem cells have always been a heated research topic in bone tissue regeneration and repair because of their...
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Effect of photobiomodulation on the behaviour of mesenchymal stem cells in three-dimensional cultures
Photobiomodulation (PBM) has been proposed as a strategy to improve the regenerative capacity of human adipose-derived stem cells (hASCs). Yet, this...
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Cytokine expression in gingival crevicular fluid around teeth opposing dental implants and 3-unit fixed partial dentures in a cross-sectional study
ObjectiveThis study aimed to study the cytokines in gingival crevicular fluid (GCF) of the teeth opposing to dental implants and 3-unit fixed partial...
