Search
Search Results
-
Anticholinergic exposure and its association with dementia/Alzheimer's disease and mortality in older adults
BackgroundUse of anticholinergic (ACH) medications is associated with increased risk of cognitive decline in the elderly. However, little is known...
-
Anxiety disorders are associated with verbal memory impairment in patients with Parkinson’s disease without dementia
IntroductionPreliminary evidence has demonstrated a link between anxiety and memory impairment in Parkinson’s disease (PD). This study further...
-
Spirituality and Spiritual Distress in Parkinson’s Disease Caregivers: A Sco** Review
Despite recognition that spiritual concerns contribute to caregiver burden, little is known about spirituality, spiritual well-being, and spiritual...
-
GBA-associated Parkinson’s disease in Hungary: clinical features and genetic insights
IntroductionParkinson’s disease (PD) has a complex genetic background involving both rare and common genetic variants. Although a small percentage of...
-
Mesenchymal stromal cell biotherapy for Parkinson’s disease premotor symptoms
Parkinson’s disease (PD) is a neurodegenerative disorder with motor deficits due to nigrostriatal dopamine depletion and with the non-motor/premotor...
-
Immune responses to oligomeric α-synuclein in Parkinson’s disease peripheral blood mononuclear cells
Parkinson’s disease displays clinical heterogeneity, presenting with motor and non-motor symptoms. Heterogeneous phenotypes, named brain-first and...
-
Impact of autonomic symptoms on the clinical course of Parkinson’s disease
PurposePatients with Parkinson’s disease (PD) exhibit various degrees of autonomic symptoms, which may be associated with Lewy body pathology...
-
Pharyngeal Structure and Dysphagia in Patients with Parkinson’s Disease and Related Disorders
AbstractPharyngeal muscle changes occur in patients with Parkinson’s disease and related disorders (PRD); however, the association between the...
-
Plasma glial fibrillary acidic protein as a biomarker of disease progression in Parkinson’s disease: a prospective cohort study
BackgroundReactive astrogliosis has been demonstrated to have a role in Parkinson’s disease (PD); however, astrocyte-specific plasma glial fibrillary...
-
The brain-first vs. body-first model of Parkinson’s disease with comparison to alternative models
The ultimate origin of Lewy body disorders, including Parkinson’s disease (PD) and Dementia with Lewy bodies (DLB), is still incompletely understood....
-
Parkinson’s disease therapy: what lies ahead?
The worldwide prevalence of Parkinson’s disease (PD) has been constantly increasing in the last decades. With rising life expectancy, a longer...
-
Correlation of olfactory function factors with cardiac sympathetic denervation in Parkinson’s disease
BackgroundHyposmia is a common nonmotor symptom of Parkinson’s disease (PD) and reportedly associated with dysautonomia in PD. The smell...
-
Economic burden of Parkinson’s disease and research trends: a bibliometric analysis
BackgroundParkinson’s disease (PD) is a neurodegenerative disorder associated with a range of motor and non-motor symptom leading to progressive...
-
Hypotensive episodes at 24-h ambulatory blood pressure monitoring predict adverse outcomes in Parkinson’s disease
PurposeNeurogenic orthostatic hypotension (nOH) is a frequent nonmotor feature of Parkinson’s disease (PD), associated with adverse outcomes....
-
The Impact of Polypharmacy on Management of Lower Urinary Tract Symptoms in Parkinson’s Disease
Lower urinary tract (LUT) symptoms are a common presentation of autonomic dysfunction in Parkinson’s disease (PD). Symptoms significantly impact...
-
Relationship between plasma NFL and disease progression in Parkinson’s disease: a prospective cohort study
ObjectiveWe aimed to examine the longitudinal change of plasma neurofilament light chain (NFL) level and explore its diagnostic and prognostic...
-
Early onset Parkinson’s disease in the cycle of 3,4-methylenedioxymethamphetamine and substance use: a case report
BackgroundCurrent evidence linking the development of Parkinson’s disease after the use of 3,4-methylenedioxymethamphetamine is mixed and limited,...
-
Structural and Functional Imaging Correlates of Visual Hallucinations in Parkinson’s Disease
Purpose of ReviewTo review recent structural and functional MRI studies of visual hallucinations in Parkinson’s disease.
Recent Findings ...
-
Diagnostic value of plasma SIRT1 levels and whole-brain gray matter volume in Parkinson’s disease patients with cognitive impairment
ObjectiveThis study was designed to investigate the diagnostic value of plasma SIRT1 levels and whole-brain gray matter (GM) volume in Parkinson’s...
-
Updates in Fluid, Tissue, and Imaging Biomarkers for Dementia with Lewy Bodies and Implications for Biologically Based Disease Definitions
Purpose of ReviewDementia with Lewy bodies (DLB) remains underrecognized and underdiagnosed due to its clinical and pathological heterogeneity....