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Adipose Tissue Inflammation and Cardiovascular Disease: An Update
Purpose of ReviewThe obesity epidemic is on the rise, and while it is well known that obesity is associated with an increase in cardiovascular risk...
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Adipose tissue function and insulin sensitivity in syndromic obesity of Bardet-Biedl syndrome
BackgroundBardet–Biedl syndrome (BBS) is a rare autosomal recessive syndromic obesity of childhood onset among many other features. To date, the...
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Adipose-derived extracellular vesicles – a novel cross-talk mechanism in insulin resistance, non-alcoholic fatty liver disease, and polycystic ovary syndrome
Obesity is the best described risk factor for the development of non-alcoholic fatty liver disease (NAFLD)/metabolic dysfunction associated steatotic...
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Association of fat mass and obesity-associated (FTO) gene polymorphisms with non-communicable diseases (NCDs) in the Iranian population: A systematic review of observational studies
BackgroundSingle nucleotide polymorphisms have been implicated in various diseases, most notably non-communicable diseases (NCDs). The aim of this...
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Altered leptin level in autism spectrum disorder and meta-analysis of adipokines
BackgroundIncreasing evidence suggests that leptin is involved in the pathology of autism spectrum disorder (ASD). In this study, our objective was...
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Obesity as a comorbidity in children and adolescents with autoimmune rheumatic diseases
Childhood obesity is the public health issue with alarming rates recorded throughout developed world and an important modifiable health risk for...
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Predictive and diagnostic biomarkers for gestational diabetes and its associated metabolic and cardiovascular diseases
Gestational diabetes mellitus (GDM) is defined as the presence of high blood glucose levels with the onset, or detected for the first time during...
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Biomarkers in axial spondyloarthritis and low back pain: a comprehensive review
The spectrum of axial spondyloarthritis (AxSpA) (including both non-radiographic and radiographic AxSpA), also known as ankylosing spondylitis AS,...
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Identifying blood biomarkers for type 2 diabetes subty**: a report from the ORIGIN trial
Aims/hypothesisIndividuals with diabetes can be clustered into five subtypes using up to six routinely measured clinical variables. We hypothesised...
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Senescent skeletal cells cross-talk with synovial cells plays a key role in the pathogenesis of osteoarthritis
Osteoarthritis (OA) has been recognized as an age-related degenerative disease commonly seen in the elderly that affects the whole “organ” including...
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Molecular mechanisms of endothelial dysfunction in coronary microcirculation dysfunction
Coronary microvascular endothelial cells (CMECs) react to changes in coronary blood flow and myocardial metabolites and regulate coronary blood flow...
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Cardiometabolic-based chronic disease: adiposity and dysglycemia drivers of heart failure
Heart failure (HF) is a complex clinical syndrome, associated with high rates of mortality, hospitalization, and impairment of quality of life....
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The Apo gene's genetic variants: hidden role in Asian vascular risk
Vascular risk factors, including diabetes, hypertension, hyperlipidemia, and obesity, pose significant health threats with implications extending to...
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Epicardial adipose tissue in contemporary cardiology
Interest in epicardial adipose tissue (EAT) is growing rapidly, and research in this area appeals to a broad, multidisciplinary audience. EAT is...
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Mechanisms of obesity- and diabetes mellitus-related pancreatic carcinogenesis: a comprehensive and systematic review
Research on obesity- and diabetes mellitus (DM)-related carcinogenesis has expanded exponentially since these two diseases were recognized as...
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Assessing the Impact of Bariatric Surgery on Retinol-Binding Protein 4 (RBP4): A Systematic Review and Meta-Analysis
This study aimed to analyze changes in retinol-binding protein 4 (RBP4) levels before and after bariatric surgery in obese individuals. Bariatric...
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Assessment of atrial conduction time and P-wave dispersion in patients with gestational diabetes mellitus
ObjectivesWe aimed to assess atrial conduction time and P-wave dispersion (PWD) in gestational diabetes mellitus (GDM) patients.
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Psoriasis and Molecular Target Therapies: Evidence of Efficacy in Preventing Cardiovascular Comorbidities
Psoriasis is now considered a systemic disease, and several comorbidities have been described such as cardiovascular diseases, neurologic and...
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Correlation Between Circulating Adropin Levels and Patients with PCOS: An Updated Systematic Review and Meta-analysis
An increasing number of young women suffer from polycystic ovary syndrome (PCOS). Reasonable diagnosis and monitoring are important steps in the...
