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Autoimmune retinopathy in a patient with smoldering multiple myeloma: a case report
PurposeMultiple myeloma (MM) is a plasma cell dyscrasia leading to proliferation of monoclonal plasma cells. Ocular involvement in multiple myeloma...
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Current Advances in Multiple Myeloma: A Post International Myeloma Society (IMS 2022) Round Table Debate by the International Academy for Clinical Hematology (IACH)
This round table discussion organized by the International Academy for Clinical Hematology (IACH) was dedicated to the 19th annual meeting of the...
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Lipid metabolic vulnerabilities of multiple myeloma
Multiple myeloma (MM) is the second most common hematological malignancy worldwide, characterized by abnormal proliferation of malignant plasma cells...
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The Impact of Panobinostat on Cell Death in Combination with S63845 in Multiple Myeloma Cells
Multiple myeloma is a B cell neoplasm characterized by bone marrow infiltration with malignant plasma cells. The Overexpression of histone...
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Excellent long-term pain response and local control following postoperative radiotherapy in patients with multiple myeloma
PurposeMultiple myeloma is associated with osteolytic bone lesions, often requiring surgery of the spine and postoperative radiotherapy (RT)....
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Multiple myeloma initially manifesting as a solitary deep ulcer on the tongue: a case study and literature review
BackgroundMultiple myeloma (MM) is a malignant disease associated with clonal plasma cell proliferative disorder, characterized by extensive...
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Exploring the role of histone deacetylase and histone deacetylase inhibitors in the context of multiple myeloma: mechanisms, therapeutic implications, and future perspectives
Histone deacetylase inhibitors (HDACis) are a significant category of pharmaceuticals that have developed in the past two decades to treat multiple...
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Incidental multiple myeloma in a patient with neuroretinitis: a case report
BackgroundNeuroretinitis is classically defined as a clinical triad of unilateral, painless vision loss, accompanied by optic disc edema and...
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Real-world treatment outcomes of carfilzomib plus dexamethasone in patients with relapsed and/or refractory multiple myeloma, focusing on the impact of trial-fitness: CAtholic REsearch network for Multiple Myeloma study (CAREMM-2203)
IntroductionCarfilzomib plus dexamethasone (Kd) is widely used in patients with relapsed and/or refractory multiple myeloma (RRMM). However, the...
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Current progress of CAR-T-cell therapy for patients with multiple myeloma
Currently available chimeric antigen receptor (CAR)-engineered T-cell therapies targeting B-cell maturation antigen (BCMA), namely, idecabtagene...
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Dietary and microbiome evidence in multiple myeloma and other plasma cell disorders
Multiple Myeloma (MM) remains an incurable plasma cell neoplasm. Although little is known about the etiology of MM, several metabolic risk factors...
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Management of patients with multiple myeloma and COVID-19 in the post pandemic era: a consensus paper from the European Myeloma Network (EMN)
In the post-pandemic COVID-19 period, human activities have returned to normal and COVID-19 cases are usually mild. However, patients with multiple...
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Lactate Decreases Bortezomib Sensitivity and Predicts Poor Clinical Outcomes of Multiple Myeloma
ObjectiveMetabolic disorders are regarded as hallmarks of multiple myeloma (MM) and are responsible for rapid cancer cell proliferation and tumor...
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Anti-tumor effect of dandelion flavone on multiple myeloma cells and its mechanism
BackgroundMultiple myeloma (MM) is a prevalent hematologic malignancy characterized by the uncontrolled proliferation of monoclonal plasma cells in...
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Real-world data on induction therapy in patients with transplant-ineligible newly diagnosed multiple myeloma: retrospective analysis of 598 cases from Kansai Myeloma Forum
To investigate the real-world clinical outcomes and management of novel drug-containing therapies for newly diagnosed multiple myeloma (MM) patients,...
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Non-producer multiple myeloma presenting with acute hyperammonemic encephalopathy: case report
BackgroundHyperammonemic encephalopathy (HE) is a rare and life-threatening complication of multiple myeloma, with underlying mechanisms that are not...
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Multiple myeloma with central nervous system relapse: a case report
A 62-year-old female patient with multiple myeloma presented with progressive analgetic-resistant headache. Cranial magnetic resonance imaging and...
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MiR-34c-5p Inhibition Affects Bax/Bcl2 Expression and Reverses Bortezomib Resistance in Multiple Myeloma Cells
Develo** resistance to anticancer drugs complicates the clinical treatment of multiple myeloma patients. Previous studies revealed a link between...
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Effects of early palliative care integration on patients with newly diagnosed multiple myeloma
PurposeWhile numerous studies underscore the benefits of early palliative care (EPC) for patients with solid tumors, its effects on patients with...
